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• W4311171489 endingPage "100815" @default.
• W4311171489 startingPage "100815" @default.
• W4311171489 abstract "Trypanosoma cruzi is the etiological agent of Chagas disease, a neglected and frequently occurring zoonosis in Central and South American countries. Wild mammals and domestic dogs are the main reservoirs of the parasite in the wild and domestic cycles, respectively. The vectors have a wide variety of food sources that can influence transmission cycles. The aim of this study was to determine the prevalence of T. cruzi infection in donkeys (Equus asininos) and mules (Equus mulus) living in rural areas of the Brazilian semi-arid region. Whole-blood samples from 72 equids (65 donkeys and 7 mules) were analyzed by nested polymerase chain reaction (nested PCR). A total of 51.39% of the samples (37/72) were positive. Phylogenetic analysis identified discrete typing units TcI and TcII, which suggested the possibility that donkeys and mules might be participating in domestic/peridomestic and wild transmission cycles. This was the first report of T. cruzi infection in donkeys and mules in Brazil, with high prevalence of positive animals. This places these animals as potential reservoirs for the parasite and the particular features of these hosts, the presence of vectors and the socioeconomic characteristics of the population under semiarid conditions create interactions that may favor transmission and overlapping T. cruzi infection cycles." @default.
• W4311171489 created "2022-12-24" @default.
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• W4311171489 date "2023-01-01" @default.
• W4311171489 modified "2023-10-02" @default.
• W4311171489 title "Molecular detection of Trypanosoma cruzi in equids in a semiarid zone of Pernambuco - Brazil" @default.
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• W4311171489 doi "https://doi.org/10.1016/j.vprsr.2022.100815" @default.
• W4311171489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36623895" @default.
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