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• W4311178384 endingPage "30" @default.
• W4311178384 startingPage "1" @default.
• W4311178384 abstract "Erectile dysfunction (ED) is one of the most common chronic diseases affecting men and its incidence increases with aging. Due to its substantial influence on the quality of life, phosphodiesterase type-5 (PDE5) inhibitors have been implemented to treat ED by increasing the penile blood flow that results in improving erection. PDE5 inhibitors is a class of drugs that affects many pharmacological sectors, and it is essential to review the different analytical methods described for their determination. Few reviews were published concerning this group of drugs. For this reason, this review article gathers the different analytical methods used to determine PDE5 inhibitors in pharmaceutical and biological samples over the past 20 years. Different analytical techniques were used to analyze these compounds in different matrices such as separation methods (capillary electrophoresis, LC-MS, UPLC-MS/MS, and GC-MS), spectroscopic methods (UV-visible methods, FT-IR spectroscopy and spectrofluorometry) and electrochemical methods (polarography, voltammetry and potentiometry). This review focuses on the different electrochemical methods and their use in analytical determination of PDE5 inhibitors in pharmaceutical dosage forms and biological samples. Moreover, it discusses the different modified electrodes used for their electroanalytical determination and the behavior of the studied drugs at different modified electrodes. Additionally, this review discusses the pharmacokinetics of the studied compounds and their interactions with other co-administered drugs especially the metabolic interactions between the studied compounds and other co-administered drugs in different matrices. This literature survey would provide a beneficial guide for future analytical investigation of PDE5 inhibitors." @default.
• W4311178384 created "2022-12-24" @default.
• W4311178384 creator A5004804844 @default.
• W4311178384 creator A5026038790 @default.
• W4311178384 creator A5033182861 @default.
• W4311178384 creator A5039642554 @default.
• W4311178384 date "2022-12-12" @default.
• W4311178384 modified "2023-10-05" @default.
• W4311178384 title "A Comprehensive Review on Analytical Techniques for Determination of Sex Stimulants, PDE5 Inhibitors in Different Matrices with Special Focus on the Electroanalytical Methods" @default.
• W4311178384 cites W1017969722 @default.
• W4311178384 cites W1865633893 @default.
• W4311178384 cites W190183808 @default.
• W4311178384 cites W1966753957 @default.
• W4311178384 cites W1970856795 @default.
• W4311178384 cites W1971220864 @default.
• W4311178384 cites W1971443263 @default.
• W4311178384 cites W1971812149 @default.
• W4311178384 cites W1972057544 @default.
• W4311178384 cites W1974756485 @default.
• W4311178384 cites W1975083387 @default.
• W4311178384 cites W1977503987 @default.
• W4311178384 cites W1979217804 @default.
• W4311178384 cites W1979940751 @default.
• W4311178384 cites W1985526194 @default.
• W4311178384 cites W1987415901 @default.
• W4311178384 cites W1988083060 @default.
• W4311178384 cites W1988460752 @default.
• W4311178384 cites W1991234474 @default.
• W4311178384 cites W1992545479 @default.
• W4311178384 cites W1994767565 @default.
• W4311178384 cites W1995295487 @default.
• W4311178384 cites W1996672603 @default.
• W4311178384 cites W1998147076 @default.
• W4311178384 cites W2007063715 @default.
• W4311178384 cites W2007933654 @default.
• W4311178384 cites W2017296850 @default.
• W4311178384 cites W2018590999 @default.
• W4311178384 cites W2021360547 @default.
• W4311178384 cites W2022204279 @default.
• W4311178384 cites W2029550970 @default.
• W4311178384 cites W2030390461 @default.
• W4311178384 cites W2034999158 @default.
• W4311178384 cites W2038758857 @default.
• W4311178384 cites W2039963846 @default.
• W4311178384 cites W2040037687 @default.
• W4311178384 cites W2040942287 @default.
• W4311178384 cites W2044261641 @default.
• W4311178384 cites W2045167038 @default.
• W4311178384 cites W2046047167 @default.
• W4311178384 cites W2049596787 @default.
• W4311178384 cites W2049998022 @default.
• W4311178384 cites W2050729791 @default.
• W4311178384 cites W2055445255 @default.
• W4311178384 cites W2058221213 @default.
• W4311178384 cites W2060341378 @default.
• W4311178384 cites W2060960672 @default.
• W4311178384 cites W2063043490 @default.
• W4311178384 cites W2063359167 @default.
• W4311178384 cites W2063529646 @default.
• W4311178384 cites W2068294505 @default.
• W4311178384 cites W2068447278 @default.
• W4311178384 cites W2070128264 @default.
• W4311178384 cites W2072958347 @default.
• W4311178384 cites W2074493780 @default.
• W4311178384 cites W2074656987 @default.
• W4311178384 cites W2076947055 @default.
• W4311178384 cites W2077940538 @default.
• W4311178384 cites W2079717519 @default.
• W4311178384 cites W2079974800 @default.
• W4311178384 cites W2080093018 @default.
• W4311178384 cites W2080882519 @default.
• W4311178384 cites W2084856702 @default.
• W4311178384 cites W2099419390 @default.
• W4311178384 cites W2113853956 @default.
• W4311178384 cites W2115543552 @default.
• W4311178384 cites W2121669501 @default.
• W4311178384 cites W2127425210 @default.
• W4311178384 cites W2135855886 @default.
• W4311178384 cites W2142391353 @default.
• W4311178384 cites W2143520796 @default.
• W4311178384 cites W2150075786 @default.
• W4311178384 cites W2157533040 @default.
• W4311178384 cites W2159885935 @default.
• W4311178384 cites W2162004917 @default.
• W4311178384 cites W2182474441 @default.
• W4311178384 cites W2183646717 @default.
• W4311178384 cites W2191258798 @default.
• W4311178384 cites W2239837503 @default.
• W4311178384 cites W2249439646 @default.
• W4311178384 cites W2256719590 @default.
• W4311178384 cites W2319567920 @default.
• W4311178384 cites W2340161982 @default.
• W4311178384 cites W2346098528 @default.
• W4311178384 cites W2395569037 @default.
• W4311178384 cites W2425035616 @default.
• W4311178384 cites W2460726390 @default.
• W4311178384 cites W2480174989 @default.
• W4311178384 cites W2530825469 @default.

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