FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311220512> ?p ?o ?g. }

• W4311220512 abstract "The microbiome of upper respiratory tract (URT) acts as a gatekeeper to respiratory health of the host. However, little is still known about the impacts of SARS-CoV-2 infection on the microbial species composition and co-occurrence correlations of the URT microbiome, especially the relationships between SARS-CoV-2 and other microbes. Here, we characterized the URT microbiome based on RNA metagenomic-sequencing datasets from 1737 nasopharyngeal samples collected from COVID-19 patients. The URT-microbiome network consisting of bacteria, archaea, and RNA viruses was built and analyzed from aspects of core/periphery species, cluster composition, and balance between positive and negative interactions. It is discovered that the URT microbiome in the COVID-19 patients is enriched with Enterobacteriaceae, a gut associated family containing many pathogens. These pathogens formed a dense cooperative guild that seemed to suppress beneficial microbes collectively. Besides bacteria and archaea, 72 eukaryotic RNA viruses were identified in the URT microbiome of COVID-19 patients. Only five of these viruses were present in more than 10% of all samples, including SARS-CoV-2 and a bat coronavirus (i.e., BatCoV BM48-31) not detected in humans by routine means. SARS-CoV-2 was inhibited by a cooperative alliance of 89 species, but seems to cooperate with BatCoV BM48-31 given their statistically significant, positive correlations. The presence of cooperative bat-coronavirus partner of SARS-CoV-2 (BatCoV BM48-31), which was previously discovered in bat but not in humans to the best of our knowledge, is puzzling and deserves further investigation given their obvious implications. Possible microbial translocation mechanism from gut to URT also deserves future studies." @default.
• W4311220512 created "2022-12-24" @default.
• W4311220512 creator A5032612435 @default.
• W4311220512 creator A5037021459 @default.
• W4311220512 date "2022-12-13" @default.
• W4311220512 modified "2023-09-24" @default.
• W4311220512 title "The Upper Respiratory Tract Microbiome Network Impacted by SARS-CoV-2" @default.
• W4311220512 cites W1588999779 @default.
• W4311220512 cites W1969359874 @default.
• W4311220512 cites W1993577573 @default.
• W4311220512 cites W2101063972 @default.
• W4311220512 cites W2146476358 @default.
• W4311220512 cites W2159954944 @default.
• W4311220512 cites W2161225919 @default.
• W4311220512 cites W2166358290 @default.
• W4311220512 cites W2195009776 @default.
• W4311220512 cites W2223503000 @default.
• W4311220512 cites W2298153446 @default.
• W4311220512 cites W2345658906 @default.
• W4311220512 cites W2462090727 @default.
• W4311220512 cites W2496661162 @default.
• W4311220512 cites W2561758149 @default.
• W4311220512 cites W2601068128 @default.
• W4311220512 cites W2761654301 @default.
• W4311220512 cites W2766099743 @default.
• W4311220512 cites W2773939681 @default.
• W4311220512 cites W2784274017 @default.
• W4311220512 cites W2921173578 @default.
• W4311220512 cites W2952152744 @default.
• W4311220512 cites W2982041933 @default.
• W4311220512 cites W2983462094 @default.
• W4311220512 cites W2990618091 @default.
• W4311220512 cites W2990919242 @default.
• W4311220512 cites W3000051506 @default.
• W4311220512 cites W3001883374 @default.
• W4311220512 cites W3004280078 @default.
• W4311220512 cites W3016078614 @default.
• W4311220512 cites W3016655060 @default.
• W4311220512 cites W3024721724 @default.
• W4311220512 cites W3027434935 @default.
• W4311220512 cites W3030412499 @default.
• W4311220512 cites W3039912799 @default.
• W4311220512 cites W3041985244 @default.
• W4311220512 cites W3099001354 @default.
• W4311220512 cites W3101528479 @default.
• W4311220512 cites W3103882533 @default.
• W4311220512 cites W3111336046 @default.
• W4311220512 cites W3118531686 @default.
• W4311220512 cites W3128287277 @default.
• W4311220512 cites W3129102895 @default.
• W4311220512 cites W3136680670 @default.
• W4311220512 cites W3137491981 @default.
• W4311220512 cites W3154743807 @default.
• W4311220512 cites W3159489040 @default.
• W4311220512 cites W3162132240 @default.
• W4311220512 cites W3170560273 @default.
• W4311220512 cites W3184130481 @default.
• W4311220512 cites W3193495330 @default.
• W4311220512 cites W3196235362 @default.
• W4311220512 cites W3211228774 @default.
• W4311220512 cites W3212598764 @default.
• W4311220512 cites W4220824075 @default.
• W4311220512 doi "https://doi.org/10.1007/s00248-022-02148-9" @default.
• W4311220512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36509943" @default.
• W4311220512 hasPublicationYear "2022" @default.
• W4311220512 type Work @default.
• W4311220512 citedByCount "1" @default.
• W4311220512 countsByYear W43112205122023 @default.
• W4311220512 crossrefType "journal-article" @default.
• W4311220512 hasAuthorship W4311220512A5032612435 @default.
• W4311220512 hasAuthorship W4311220512A5037021459 @default.
• W4311220512 hasBestOaLocation W43112205121 @default.
• W4311220512 hasConcept C104317684 @default.
• W4311220512 hasConcept C105702510 @default.
• W4311220512 hasConcept C142724271 @default.
• W4311220512 hasConcept C143121216 @default.
• W4311220512 hasConcept C15151743 @default.
• W4311220512 hasConcept C159047783 @default.
• W4311220512 hasConcept C190139176 @default.
• W4311220512 hasConcept C190743605 @default.
• W4311220512 hasConcept C2776012195 @default.
• W4311220512 hasConcept C2777648638 @default.
• W4311220512 hasConcept C2779134260 @default.
• W4311220512 hasConcept C3008058167 @default.
• W4311220512 hasConcept C523546767 @default.
• W4311220512 hasConcept C524204448 @default.
• W4311220512 hasConcept C534529494 @default.
• W4311220512 hasConcept C54355233 @default.
• W4311220512 hasConcept C550995028 @default.
• W4311220512 hasConcept C67705224 @default.
• W4311220512 hasConcept C69562835 @default.
• W4311220512 hasConcept C71924100 @default.
• W4311220512 hasConcept C86803240 @default.
• W4311220512 hasConcept C89423630 @default.
• W4311220512 hasConceptScore W4311220512C104317684 @default.
• W4311220512 hasConceptScore W4311220512C105702510 @default.
• W4311220512 hasConceptScore W4311220512C142724271 @default.
• W4311220512 hasConceptScore W4311220512C143121216 @default.
• W4311220512 hasConceptScore W4311220512C15151743 @default.
• W4311220512 hasConceptScore W4311220512C159047783 @default.

• next