Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311277997> ?p ?o ?g. }
- W4311277997 endingPage "24524" @default.
- W4311277997 startingPage "24517" @default.
- W4311277997 abstract "Natural and biodegradable polymers with pH-responsive properties, such as alginate and chitosan, are widely exploited for drug delivery applications, most notably in the form of biocompatible microspheres. In addition, thermo-responsive poly(N-isopropyl-acrylamide) (PNIPAM) is often added to biomedical delivery systems due to its lower critical solution temperature close to human physiological conditions. In this work, multi-responsive microspheres (MRMs) consisting of a hydrogel matrix made of alginate, chitosan, and PNIPAM were successfully prepared by extrusion dripping and proposed as delivery system for Ozoile (Stable Ozonides) derived from biological olive oil. Ozoile acts as a biological inducer, regulating the main metabolic pathways and stimulating the endogenous defence system. The MRMs containing Ozoile were prepared from alginate/NIPAM emulsions integrating the lipophilic bioactive principle. The MRMs were further optimised with a chitosan coating to improve their stability and control the degradation behaviour of the hydrogel matrix, with subsequent release of Ozoile. Results in terms of chemical composition from Fourier transform infrared (FTIR) spectroscopy, thermo-responsive properties from differential scanning calorimetry (DSC) analysis, swelling and degradation behaviour were used to establish the potential use of the MRMs for the therapeutic release of Ozoile at specific inflammatory sites." @default.
- W4311277997 created "2022-12-25" @default.
- W4311277997 creator A5010669543 @default.
- W4311277997 creator A5066262156 @default.
- W4311277997 creator A5070460076 @default.
- W4311277997 creator A5091760045 @default.
- W4311277997 date "2023-07-01" @default.
- W4311277997 modified "2023-09-29" @default.
- W4311277997 title "Emulsion-based multi-responsive microspheres for the delivery of lipophilic Ozoile" @default.
- W4311277997 cites W1963678292 @default.
- W4311277997 cites W1969889020 @default.
- W4311277997 cites W1974373270 @default.
- W4311277997 cites W1975818276 @default.
- W4311277997 cites W1986601289 @default.
- W4311277997 cites W1993577221 @default.
- W4311277997 cites W1994846102 @default.
- W4311277997 cites W1999990475 @default.
- W4311277997 cites W2021804758 @default.
- W4311277997 cites W2044801888 @default.
- W4311277997 cites W2044894878 @default.
- W4311277997 cites W2048366953 @default.
- W4311277997 cites W2063362588 @default.
- W4311277997 cites W2084408869 @default.
- W4311277997 cites W2092768320 @default.
- W4311277997 cites W2120949673 @default.
- W4311277997 cites W2129943573 @default.
- W4311277997 cites W2143336942 @default.
- W4311277997 cites W2272533603 @default.
- W4311277997 cites W2474221146 @default.
- W4311277997 cites W2539107597 @default.
- W4311277997 cites W2575295892 @default.
- W4311277997 cites W263642913 @default.
- W4311277997 cites W2730801656 @default.
- W4311277997 cites W2766760929 @default.
- W4311277997 cites W2769840171 @default.
- W4311277997 cites W2788489069 @default.
- W4311277997 cites W2789282587 @default.
- W4311277997 cites W2790771480 @default.
- W4311277997 cites W2794766178 @default.
- W4311277997 cites W2796008581 @default.
- W4311277997 cites W2805176360 @default.
- W4311277997 cites W2810235771 @default.
- W4311277997 cites W2940353886 @default.
- W4311277997 cites W2941782487 @default.
- W4311277997 cites W2958296989 @default.
- W4311277997 cites W2963332584 @default.
- W4311277997 cites W2990134901 @default.
- W4311277997 cites W2997964560 @default.
- W4311277997 cites W3009046733 @default.
- W4311277997 cites W3036760574 @default.
- W4311277997 cites W3088433896 @default.
- W4311277997 cites W3127740703 @default.
- W4311277997 cites W4206981330 @default.
- W4311277997 cites W4213169804 @default.
- W4311277997 cites W4233902228 @default.
- W4311277997 cites W4281847255 @default.
- W4311277997 doi "https://doi.org/10.1016/j.ceramint.2022.12.095" @default.
- W4311277997 hasPublicationYear "2023" @default.
- W4311277997 type Work @default.
- W4311277997 citedByCount "2" @default.
- W4311277997 countsByYear W43112779972023 @default.
- W4311277997 crossrefType "journal-article" @default.
- W4311277997 hasAuthorship W4311277997A5010669543 @default.
- W4311277997 hasAuthorship W4311277997A5066262156 @default.
- W4311277997 hasAuthorship W4311277997A5070460076 @default.
- W4311277997 hasAuthorship W4311277997A5091760045 @default.
- W4311277997 hasConcept C121332964 @default.
- W4311277997 hasConcept C127413603 @default.
- W4311277997 hasConcept C159985019 @default.
- W4311277997 hasConcept C160892712 @default.
- W4311277997 hasConcept C171250308 @default.
- W4311277997 hasConcept C192562407 @default.
- W4311277997 hasConcept C2778123984 @default.
- W4311277997 hasConcept C2778414984 @default.
- W4311277997 hasConcept C2778540859 @default.
- W4311277997 hasConcept C2779732960 @default.
- W4311277997 hasConcept C2779820397 @default.
- W4311277997 hasConcept C39519442 @default.
- W4311277997 hasConcept C42360764 @default.
- W4311277997 hasConcept C521977710 @default.
- W4311277997 hasConcept C97355855 @default.
- W4311277997 hasConceptScore W4311277997C121332964 @default.
- W4311277997 hasConceptScore W4311277997C127413603 @default.
- W4311277997 hasConceptScore W4311277997C159985019 @default.
- W4311277997 hasConceptScore W4311277997C160892712 @default.
- W4311277997 hasConceptScore W4311277997C171250308 @default.
- W4311277997 hasConceptScore W4311277997C192562407 @default.
- W4311277997 hasConceptScore W4311277997C2778123984 @default.
- W4311277997 hasConceptScore W4311277997C2778414984 @default.
- W4311277997 hasConceptScore W4311277997C2778540859 @default.
- W4311277997 hasConceptScore W4311277997C2779732960 @default.
- W4311277997 hasConceptScore W4311277997C2779820397 @default.
- W4311277997 hasConceptScore W4311277997C39519442 @default.
- W4311277997 hasConceptScore W4311277997C42360764 @default.
- W4311277997 hasConceptScore W4311277997C521977710 @default.
- W4311277997 hasConceptScore W4311277997C97355855 @default.
- W4311277997 hasFunder F4320322510 @default.
- W4311277997 hasIssue "14" @default.