FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311283664> ?p ?o ?g. }

• W4311283664 endingPage "384" @default.
• W4311283664 startingPage "373" @default.
• W4311283664 abstract "Statins had been used as a cornerstone in the primary and secondary prevention of cardiovascular disease. Widespread attention had been given to the risk of bleeding, especially intracranial hemorrhage (ICH) in patients receiving statins therapy. This study aimed to determine whether statins treatment was associated with the risk of bleeding and ICH in randomized controlled trials (RCTs).Electronic databases were searched for studies up to September 8, 2022. Articles from RCTs were included in the meta-analysis if they reported the bleeding events associated with the treatment of statins or placebo/nonstatin treatment. The risk ratios (RR) of total bleeding and ICH were pooled from the number of patients with each outcome in the statins and control groups from the included studies.Twenty-nine studies comprising 145,929 individuals (2437 incident bleeding cases) were included in the meta-analysis. After a median follow-up duration of 3.65 years, statins treatment was not associated with the risk of all bleeding (RR = 1.03, 95% CI 0.93-1.15). Furthermore, in 26 studies comprising 144,177 participants, after a median follow-up duration of 3.95 years, statins treatment was not associated with the risk of ICH (RR = 1.05, 95% CI 0.84-1.31). Although in the subgroup analysis with patients with prior stroke, statins treatment showed an increased risk of ICH (RR = 1.47, 95% CI 1.07-2.01), sensitivity analysis showed that the result was unstable, which may be mainly driven by the SPARCL study.Statins therapy is not associated with the risk of all bleeding and ICH. Although a mildly increased risk of ICH in patients with prior stroke is observed, which may be caused by chance finding and warrant further documentation." @default.
• W4311283664 created "2022-12-25" @default.
• W4311283664 creator A5028370395 @default.
• W4311283664 creator A5035746415 @default.
• W4311283664 creator A5038061233 @default.
• W4311283664 creator A5055198676 @default.
• W4311283664 creator A5058869028 @default.
• W4311283664 creator A5074099894 @default.
• W4311283664 date "2022-12-01" @default.
• W4311283664 modified "2023-10-02" @default.
• W4311283664 title "Stains therapy and the risk of all bleeding and intracranial hemorrhage: A meta‐analysis of randomized controlled studies" @default.
• W4311283664 cites W1500963439 @default.
• W4311283664 cites W1546258268 @default.
• W4311283664 cites W1816597323 @default.
• W4311283664 cites W1922625321 @default.
• W4311283664 cites W1933463071 @default.
• W4311283664 cites W1965408926 @default.
• W4311283664 cites W1992798646 @default.
• W4311283664 cites W2007101617 @default.
• W4311283664 cites W2012655589 @default.
• W4311283664 cites W2015137536 @default.
• W4311283664 cites W2029605351 @default.
• W4311283664 cites W2031185570 @default.
• W4311283664 cites W2037353029 @default.
• W4311283664 cites W2039944972 @default.
• W4311283664 cites W2078205785 @default.
• W4311283664 cites W2078919468 @default.
• W4311283664 cites W2082258415 @default.
• W4311283664 cites W2098923148 @default.
• W4311283664 cites W2110601215 @default.
• W4311283664 cites W2116045728 @default.
• W4311283664 cites W2117842413 @default.
• W4311283664 cites W2126452437 @default.
• W4311283664 cites W2126563293 @default.
• W4311283664 cites W2126678006 @default.
• W4311283664 cites W2129750583 @default.
• W4311283664 cites W2134751772 @default.
• W4311283664 cites W2135631433 @default.
• W4311283664 cites W2160152341 @default.
• W4311283664 cites W2162430779 @default.
• W4311283664 cites W2165044111 @default.
• W4311283664 cites W2167574024 @default.
• W4311283664 cites W2169602692 @default.
• W4311283664 cites W2170127099 @default.
• W4311283664 cites W2170420840 @default.
• W4311283664 cites W2171390015 @default.
• W4311283664 cites W2218843182 @default.
• W4311283664 cites W2306247282 @default.
• W4311283664 cites W2552951299 @default.
• W4311283664 cites W2594861736 @default.
• W4311283664 cites W2610498431 @default.
• W4311283664 cites W2756170709 @default.
• W4311283664 cites W2771290098 @default.
• W4311283664 cites W2921012991 @default.
• W4311283664 cites W2956014568 @default.
• W4311283664 cites W2968823402 @default.
• W4311283664 cites W2972649288 @default.
• W4311283664 cites W3118615836 @default.
• W4311283664 cites W3120865803 @default.
• W4311283664 cites W3122226502 @default.
• W4311283664 cites W3153390842 @default.
• W4311283664 cites W3160263194 @default.
• W4311283664 cites W3174113810 @default.
• W4311283664 cites W3197233987 @default.
• W4311283664 cites W3203517734 @default.
• W4311283664 cites W3213249241 @default.
• W4311283664 cites W4213331590 @default.
• W4311283664 cites W4241543174 @default.
• W4311283664 cites W4280577815 @default.
• W4311283664 cites W4379439872 @default.
• W4311283664 doi "https://doi.org/10.1111/jebm.12507" @default.
• W4311283664 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36510635" @default.
• W4311283664 hasPublicationYear "2022" @default.
• W4311283664 type Work @default.
• W4311283664 citedByCount "1" @default.
• W4311283664 countsByYear W43112836642023 @default.
• W4311283664 crossrefType "journal-article" @default.
• W4311283664 hasAuthorship W4311283664A5028370395 @default.
• W4311283664 hasAuthorship W4311283664A5035746415 @default.
• W4311283664 hasAuthorship W4311283664A5038061233 @default.
• W4311283664 hasAuthorship W4311283664A5055198676 @default.
• W4311283664 hasAuthorship W4311283664A5058869028 @default.
• W4311283664 hasAuthorship W4311283664A5074099894 @default.
• W4311283664 hasConcept C126322002 @default.
• W4311283664 hasConcept C127413603 @default.
• W4311283664 hasConcept C141071460 @default.
• W4311283664 hasConcept C142724271 @default.
• W4311283664 hasConcept C168563851 @default.
• W4311283664 hasConcept C187960798 @default.
• W4311283664 hasConcept C204787440 @default.
• W4311283664 hasConcept C27081682 @default.
• W4311283664 hasConcept C2780645631 @default.
• W4311283664 hasConcept C44249647 @default.
• W4311283664 hasConcept C71924100 @default.
• W4311283664 hasConcept C78519656 @default.
• W4311283664 hasConcept C82789193 @default.
• W4311283664 hasConcept C95190672 @default.
• W4311283664 hasConceptScore W4311283664C126322002 @default.

• next