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• W4311286852 abstract "Fecal microbiota transplantation (FMT) has been well described in the treatment of pediatric diseases; however, the latest updates regarding its use in children are unclear and the concepts involved need to be revisited. We performed advanced searches in the MEDLINE, EMBASE, and Cochrane databases using the keywords “Fecal microbiota transplantation OR Fecal microbiota transfer” in the [Title/Abstract] to identify relevant articles published in English within the last five years. To identify additional studies, reference lists of review articles and included studies were manually searched. Retrieved manuscripts (case reports, reviews, and abstracts) were assessed by the authors. Among the articles, studies were based on the mechanism (n = 28), sample preparation (n = 9), delivery approaches (n = 23), safety (n = 26), and indications (n = 67), including Clostridium difficile infection (CDI) and recurrent C. difficile infection (rCDI; n = 21), non-alcoholic fatty liver disease (NAFLD; n = 10), irritable bowel syndrome (IBS; n = 5), inflammatory bowel disease (IBD; n = 15), diabetes (n = 5), functional constipation (FC; n = 4), and autism spectrum disorder (ASD; n = 7). Concepts of FMT in pediatric diseases have been updated with respect to underlying mechanisms, methodology, indications, and safety. Evidence-based clinical trials for the use of FMT in pediatric diseases should be introduced to resolve the challenges of dosage, duration, initiation, and the end point of treatment." @default.
• W4311286852 created "2022-12-25" @default.
• W4311286852 creator A5003067787 @default.
• W4311286852 creator A5051024331 @default.
• W4311286852 creator A5075076354 @default.
• W4311286852 date "2022-12-09" @default.
• W4311286852 modified "2023-10-15" @default.
• W4311286852 title "Fecal microbiota transplantation in childhood: past, present, and future" @default.
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• W4311286852 doi "https://doi.org/10.1007/s12519-022-00655-w" @default.
• W4311286852 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36484871" @default.
• W4311286852 hasPublicationYear "2022" @default.
• W4311286852 type Work @default.

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