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• W4311303735 abstract "The act of remembering an everyday experience influences how we interpret the world, how we think about the future, and how we perceive ourselves. It also enhances long-term retention of the recalled content, increasing the likelihood that it will be recalled again. Unfortunately, the ability to recollect event-specific details and reexperience the past tends to decline with age. This decline in recollection may reflect a corresponding decrease in the distinctiveness of hippocampal memory representations. Despite these well-established changes, there are few effective cognitive behavioral interventions that target real-world episodic memory. We addressed this gap by developing a smartphone-based application called HippoCamera that allows participants to record labeled videos of everyday events and subsequently replay, high-fidelity autobiographical memory cues. In two experiments, we found that older adults were able to easily integrate this noninvasive intervention into their daily lives. Using HippoCamera to repeatedly reactivate memories for real-world events improved episodic recollection and it evoked more positive autobiographical sentiment at the time of retrieval. In both experiments, these benefits were observed shortly after the intervention and again after a 3-mo delay. Moreover, more detailed recollection was associated with more differentiated memory signals in the hippocampus. Thus, using this smartphone application to systematically reactivate memories for recent real-world experiences can help to maintain a bridge between the present and past in older adults." @default.
• W4311303735 created "2022-12-25" @default.
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• W4311303735 date "2022-12-13" @default.
• W4311303735 modified "2023-10-07" @default.
• W4311303735 title "A smartphone intervention that enhances real-world memory and promotes differentiation of hippocampal activity in older adults" @default.
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• W4311303735 doi "https://doi.org/10.1073/pnas.2214285119" @default.
• W4311303735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36512503" @default.
• W4311303735 hasPublicationYear "2022" @default.
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