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- W4311304821 abstract "Closed-loop neural prostheses have been widely used as a therapeutic strategy for a range of neurological, inflammatory, and cardiac disorders. Vagus nerve stimulation has shown promising results for the monitoring and treatment of post-operation symptoms of heart transplant recipients. A prime candidate for selective control of vagal fibres is the microchannel neural interface (MNI), which provides a suitable environment for neural growth and enables effective control of the neural activity in a bidirectional system. This paper presents the design and simulation of an ASIC in 180-nm high-voltage CMOS technology, capable of concurrent stimulation and neural recording with artifact reduction in a seven-channel MNI. The analog front-end amplifies action potentials with a gain of 40 dB, presenting a common-mode rejection ratio of 81 dB at 1 kHz and a noise efficiency factor of 5.13 over the 300 Hz to 5 kHz recording bandwidth. A 42-V-compliant stimulation module operates concurrently and independently across the seven channels." @default.
- W4311304821 created "2022-12-25" @default.
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- W4311304821 date "2022-10-24" @default.
- W4311304821 modified "2023-10-14" @default.
- W4311304821 title "A Bidirectional ASIC for Active Microchannel Neural Interfaces" @default.
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- W4311304821 doi "https://doi.org/10.1109/icecs202256217.2022.9970803" @default.
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