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- W4311313031 abstract "Recently, metal‐organic frameworks (MOFs) have received a lot of interest for application in many fields ranging from catalysis, energy storage, and gas sensing to chemosensory and biomedicine owed to their flexible composition, tunable porosity, and easy functionalization ability. In particular, nanoscale MOFs have been broadly investigated as carriers for the delivery of therapeutics to cancerous organs owed to their high encapsulating capacity and controlled cargo release, versatility, biodegradability, and good biocompatibility. Several methods such as solvothermal, mechanochemical, electrochemical, microwave, and ultrasound have been utilized to fabricate MOFs via custom‐made synthesis. Many efforts have been made to functionalize MOFs through “post‐synthetic modification,” by adjusting the nature, size, and charge of the linkers or tuning its main components. Herein, a comprehensive literature review on recent papers dealing with drug‐loaded MOFs for the detection and treatment of cancer as well as bacterial, fungal, and viral infections is presented. Different types of MOFs applied as carriers in drug delivery systems and biosensing platforms are described. Furthermore, perspectives and challenges for future research in the field, particularly for cancer therapy, are discussed. Thus, very limited literature is available on in vitro and in vivo toxicity of nanoscale MOFs. Besides, their biological stability and long‐term safety are crucial factors that should be further investigated. Based on the reviewed papers, zeolite imidazolate framework (ZIF) and Materials of Institute Lavoisier (MIL) families have been the main focus for drug delivery and diagnosis applications, respectively, while many types of MOFs have exhibited antibacterial and antifungal properties regardless of their cargo." @default.
- W4311313031 created "2022-12-25" @default.
- W4311313031 creator A5015660397 @default.
- W4311313031 creator A5044699104 @default.
- W4311313031 creator A5060451693 @default.
- W4311313031 creator A5061611079 @default.
- W4311313031 creator A5062282686 @default.
- W4311313031 creator A5069053014 @default.
- W4311313031 creator A5071608603 @default.
- W4311313031 creator A5079968507 @default.
- W4311313031 date "2023-01-02" @default.
- W4311313031 modified "2023-09-30" @default.
- W4311313031 title "Nanoscale metallic‐organic frameworks as an advanced tool for medical applications: Challenges and recent progress" @default.
- W4311313031 cites W1596848781 @default.
- W4311313031 cites W1778497012 @default.
- W4311313031 cites W1868554855 @default.
- W4311313031 cites W1906394725 @default.
- W4311313031 cites W1985076352 @default.
- W4311313031 cites W1991283463 @default.
- W4311313031 cites W1993341333 @default.
- W4311313031 cites W1996352962 @default.
- W4311313031 cites W2026011899 @default.
- W4311313031 cites W2038809098 @default.
- W4311313031 cites W2041860120 @default.
- W4311313031 cites W2042138520 @default.
- W4311313031 cites W2051708290 @default.
- W4311313031 cites W2062891534 @default.
- W4311313031 cites W2066991705 @default.
- W4311313031 cites W2075080218 @default.
- W4311313031 cites W2075825895 @default.
- W4311313031 cites W2076092513 @default.
- W4311313031 cites W2078820160 @default.
- W4311313031 cites W2085057853 @default.
- W4311313031 cites W2133885408 @default.
- W4311313031 cites W2135465393 @default.
- W4311313031 cites W2148702736 @default.
- W4311313031 cites W2170811673 @default.
- W4311313031 cites W2208284809 @default.
- W4311313031 cites W2215498278 @default.
- W4311313031 cites W2262773918 @default.
- W4311313031 cites W2264560473 @default.
- W4311313031 cites W2279059353 @default.
- W4311313031 cites W2279490582 @default.
- W4311313031 cites W2283564633 @default.
- W4311313031 cites W2295783320 @default.
- W4311313031 cites W2297606889 @default.
- W4311313031 cites W2306166448 @default.
- W4311313031 cites W2320436725 @default.
- W4311313031 cites W2340774841 @default.
- W4311313031 cites W2345673877 @default.
- W4311313031 cites W2410900281 @default.
- W4311313031 cites W2422333579 @default.
- W4311313031 cites W2469936564 @default.
- W4311313031 cites W2511068407 @default.
- W4311313031 cites W2539249420 @default.
- W4311313031 cites W2539327471 @default.
- W4311313031 cites W2553703925 @default.
- W4311313031 cites W2565695863 @default.
- W4311313031 cites W2575730648 @default.
- W4311313031 cites W2575786444 @default.
- W4311313031 cites W2576924220 @default.
- W4311313031 cites W2585315127 @default.
- W4311313031 cites W2588922129 @default.
- W4311313031 cites W2590034771 @default.
- W4311313031 cites W2591580796 @default.
- W4311313031 cites W2591994927 @default.
- W4311313031 cites W2604084092 @default.
- W4311313031 cites W2620492608 @default.
- W4311313031 cites W2658837914 @default.
- W4311313031 cites W2737608110 @default.
- W4311313031 cites W2753224181 @default.
- W4311313031 cites W2755610673 @default.
- W4311313031 cites W2755666597 @default.
- W4311313031 cites W2760783534 @default.
- W4311313031 cites W2763857535 @default.
- W4311313031 cites W2766207559 @default.
- W4311313031 cites W2770803372 @default.
- W4311313031 cites W2783204299 @default.
- W4311313031 cites W2784682310 @default.
- W4311313031 cites W2795371811 @default.
- W4311313031 cites W2797906173 @default.
- W4311313031 cites W2799518824 @default.
- W4311313031 cites W2809800373 @default.
- W4311313031 cites W2810712752 @default.
- W4311313031 cites W2883768481 @default.
- W4311313031 cites W2884959146 @default.
- W4311313031 cites W2885890321 @default.
- W4311313031 cites W2886791966 @default.
- W4311313031 cites W2891331637 @default.
- W4311313031 cites W2891443608 @default.
- W4311313031 cites W2891759191 @default.
- W4311313031 cites W2896165936 @default.
- W4311313031 cites W2899767603 @default.
- W4311313031 cites W2901151296 @default.
- W4311313031 cites W2901216924 @default.
- W4311313031 cites W2906374099 @default.
- W4311313031 cites W2914314448 @default.
- W4311313031 cites W2914795017 @default.
- W4311313031 cites W2916375270 @default.
- W4311313031 cites W2917132345 @default.