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- W4311320498 abstract "The mitochondrial calcium uniporter (MCU) controls mitochondrial bioenergetics, and its activity varies greatly between tissues. Here, we highlight a recently identified MCU-EMRE-UCP1 complex, named thermoporter, in the adaptive thermogenesis of brown adipose tissue (BAT). The thermoporter enhances MCU activity to promote thermogenic metabolism, demonstrating a BAT-specific regulation for MCU activity." @default.
- W4311320498 created "2022-12-25" @default.
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- W4311320498 date "2023-03-01" @default.
- W4311320498 modified "2023-10-14" @default.
- W4311320498 title "Thermoporter: a new regulatory mechanism for mitochondrial calcium uniporter activity" @default.
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- W4311320498 doi "https://doi.org/10.1016/j.tcb.2022.11.008" @default.
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