Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311348007> ?p ?o ?g. }
- W4311348007 endingPage "87" @default.
- W4311348007 startingPage "72" @default.
- W4311348007 abstract "Hepatocellular carcinoma (HCC) is the most common primary liver cancer whose incidence continues to rise in many parts of the world due to a concomitant rise in many associated risk factors, such as alcohol use and obesity. Although early-stage HCC can be potentially curable through liver resection, liver-directed therapies, or transplantation, patients usually present with intermediate to advanced disease, which continues to be associated with a poor prognosis. This is because HCC is a cancer with significant complexities, including substantial clinical, histopathologic, and genomic heterogeneity. However, the scientific community has made a major effort to better characterize HCC in those aspects via utilizing tissue sampling and histological classification, whole genome sequencing, and developing viable animal models. These efforts ultimately aim to develop clinically relevant biomarkers and discover molecular targets for new therapies. For example, until recently, there was only one approved systemic therapy for advanced or metastatic HCC in the form of sorafenib. Through these efforts, several additional targeted therapies have gained approval in the United States, although much progress remains to be desired. This review will focus on the link between characterizing the pathogenesis of HCC with current and future HCC management." @default.
- W4311348007 created "2022-12-25" @default.
- W4311348007 creator A5007506005 @default.
- W4311348007 creator A5034942083 @default.
- W4311348007 creator A5036281932 @default.
- W4311348007 creator A5036926449 @default.
- W4311348007 creator A5036956122 @default.
- W4311348007 creator A5037346507 @default.
- W4311348007 creator A5045096676 @default.
- W4311348007 creator A5052934363 @default.
- W4311348007 creator A5055524480 @default.
- W4311348007 creator A5059904454 @default.
- W4311348007 creator A5061001986 @default.
- W4311348007 creator A5068546735 @default.
- W4311348007 creator A5069748932 @default.
- W4311348007 creator A5074071367 @default.
- W4311348007 creator A5079743290 @default.
- W4311348007 creator A5079986926 @default.
- W4311348007 creator A5085573931 @default.
- W4311348007 creator A5087121157 @default.
- W4311348007 creator A5091703176 @default.
- W4311348007 date "2022-12-13" @default.
- W4311348007 modified "2023-10-14" @default.
- W4311348007 title "Pathogenesis to management of hepatocellular carcinoma" @default.
- W4311348007 cites W1037823870 @default.
- W4311348007 cites W1051316711 @default.
- W4311348007 cites W1258381707 @default.
- W4311348007 cites W1417772029 @default.
- W4311348007 cites W1964619581 @default.
- W4311348007 cites W1965118614 @default.
- W4311348007 cites W1971837077 @default.
- W4311348007 cites W1974342793 @default.
- W4311348007 cites W1974489853 @default.
- W4311348007 cites W1977362391 @default.
- W4311348007 cites W2053435298 @default.
- W4311348007 cites W2055797954 @default.
- W4311348007 cites W2067224679 @default.
- W4311348007 cites W2067691895 @default.
- W4311348007 cites W2068127752 @default.
- W4311348007 cites W2070396671 @default.
- W4311348007 cites W2085390667 @default.
- W4311348007 cites W2093035112 @default.
- W4311348007 cites W2096753133 @default.
- W4311348007 cites W2100084607 @default.
- W4311348007 cites W2101562189 @default.
- W4311348007 cites W2127503402 @default.
- W4311348007 cites W2159106380 @default.
- W4311348007 cites W2164938105 @default.
- W4311348007 cites W2173698250 @default.
- W4311348007 cites W2241661898 @default.
- W4311348007 cites W2256023856 @default.
- W4311348007 cites W2282228285 @default.
- W4311348007 cites W2310375888 @default.
- W4311348007 cites W2315027248 @default.
- W4311348007 cites W2478303708 @default.
- W4311348007 cites W2496240332 @default.
- W4311348007 cites W2547904659 @default.
- W4311348007 cites W2552243272 @default.
- W4311348007 cites W2564751880 @default.
- W4311348007 cites W2591717879 @default.
- W4311348007 cites W2597872842 @default.
- W4311348007 cites W2612910794 @default.
- W4311348007 cites W2613598584 @default.
- W4311348007 cites W2613817387 @default.
- W4311348007 cites W2618229240 @default.
- W4311348007 cites W2625559053 @default.
- W4311348007 cites W2636014882 @default.
- W4311348007 cites W2728365508 @default.
- W4311348007 cites W2736109075 @default.
- W4311348007 cites W2756331708 @default.
- W4311348007 cites W2767233119 @default.
- W4311348007 cites W2786099441 @default.
- W4311348007 cites W2789265006 @default.
- W4311348007 cites W2789406733 @default.
- W4311348007 cites W2789547963 @default.
- W4311348007 cites W2795867722 @default.
- W4311348007 cites W2796067155 @default.
- W4311348007 cites W2799799871 @default.
- W4311348007 cites W2806581056 @default.
- W4311348007 cites W2890534939 @default.
- W4311348007 cites W2892899495 @default.
- W4311348007 cites W2894166779 @default.
- W4311348007 cites W2895308016 @default.
- W4311348007 cites W2898314774 @default.
- W4311348007 cites W2901770926 @default.
- W4311348007 cites W2904803926 @default.
- W4311348007 cites W2913384788 @default.
- W4311348007 cites W2917434424 @default.
- W4311348007 cites W2937492957 @default.
- W4311348007 cites W2944149745 @default.
- W4311348007 cites W2963440902 @default.
- W4311348007 cites W2990602950 @default.
- W4311348007 cites W2994835045 @default.
- W4311348007 cites W2995167300 @default.
- W4311348007 cites W3008345838 @default.
- W4311348007 cites W3011609327 @default.
- W4311348007 cites W3012077911 @default.
- W4311348007 cites W3016423312 @default.