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- W4311350070 abstract "Abstract Brain states, such as wake, sleep, or different depths of anesthesia are usually assessed using electrophysiological techniques, such as the local field potential (LFP) or the electro-encephalogram (EEG), which are ideal signals for detecting activity patterns such as asynchronous or oscillatory activities. However, it is technically challenging to have these type of measures during calcium imaging recordings such as two-photon or wide field techniques. Here, using simultaneous two-photon and LFP measurements, we demonstrate that despite the slower dynamics of the calcium signal, there is a high correlation between the LFP and two-photon signals taken from the neuropil outside neuronal somata. These results suggest that calcium signals alone can be used to detect activity patterns such as slow oscillations and ultimately assess the brain state." @default.
- W4311350070 created "2022-12-25" @default.
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- W4311350070 date "2022-12-13" @default.
- W4311350070 modified "2023-09-30" @default.
- W4311350070 title "Assessing brain states with two-photon calcium signals" @default.
- W4311350070 doi "https://doi.org/10.21203/rs.3.rs-2353766/v1" @default.
- W4311350070 hasPublicationYear "2022" @default.
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