FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311357718> ?p ?o ?g. }

• W4311357718 endingPage "1813" @default.
• W4311357718 startingPage "1813" @default.
• W4311357718 abstract "The results of many experimental and theoretical works indicate that after transport of protons across the mitochondrial inner membrane (MIM) in the oxidative phosphorylation (OXPHOS) system, they are retained on the membrane–water interface in nonequilibrium state with free energy excess due to low proton surface-to-bulk release. This well-established phenomenon suggests that proton trapping on the membrane interface ensures vectorial lateral transport of protons from proton pumps to ATP synthases (proton acceptors). Despite the key role of the proton transport in bioenergetics, the molecular mechanism of proton transfer in the OXPHOS system is not yet completely established. Here, we developed a dynamics model of long-range transport of energized protons along the MIM accompanied by collective excitation of localized waves propagating on the membrane surface. Our model is based on the new data on the macromolecular organization of the OXPHOS system showing the well-ordered structure of respirasomes and ATP synthases on the cristae membrane folds. We developed a two-component dynamics model of the proton transport considering two coupled subsystems: the ordered hydrogen bond (HB) chain of water molecules and lipid headgroups of MIM. We analytically obtained a two-component soliton solution in this model, which describes the motion of the proton kink, corresponding to successive proton hops in the HB chain, and coherent motion of a compression soliton in the chain of lipid headgroups. The local deformation in a soliton range facilitates proton jumps due to water molecules approaching each other in the HB chain. We suggested that the proton-conducting structures formed along the cristae membrane surface promote direct lateral proton transfer in the OXPHOS system. Collective excitations at the water–membrane interface in a form of two-component soliton ensure the coupled non-dissipative transport of charge carriers and elastic energy of MIM deformation to ATP synthases that may be utilized in ATP synthesis providing maximal efficiency in mitochondrial bioenergetics." @default.
• W4311357718 created "2022-12-25" @default.
• W4311357718 creator A5015518861 @default.
• W4311357718 creator A5024371860 @default.
• W4311357718 creator A5043393074 @default.
• W4311357718 creator A5048104678 @default.
• W4311357718 creator A5086561075 @default.
• W4311357718 date "2022-12-13" @default.
• W4311357718 modified "2023-10-06" @default.
• W4311357718 title "Contribution of the Collective Excitations to the Coupled Proton and Energy Transport along Mitochondrial Cristae Membrane in Oxidative Phosphorylation System" @default.
• W4311357718 cites W1563966206 @default.
• W4311357718 cites W1964911067 @default.
• W4311357718 cites W1966538532 @default.
• W4311357718 cites W1968324960 @default.
• W4311357718 cites W1977678690 @default.
• W4311357718 cites W1979987988 @default.
• W4311357718 cites W1985319562 @default.
• W4311357718 cites W1990625705 @default.
• W4311357718 cites W1994732772 @default.
• W4311357718 cites W1999040292 @default.
• W4311357718 cites W2005392128 @default.
• W4311357718 cites W2008225906 @default.
• W4311357718 cites W2020328235 @default.
• W4311357718 cites W2029663082 @default.
• W4311357718 cites W2031079887 @default.
• W4311357718 cites W2031227547 @default.
• W4311357718 cites W2037176665 @default.
• W4311357718 cites W2037613903 @default.
• W4311357718 cites W2041622164 @default.
• W4311357718 cites W2042183674 @default.
• W4311357718 cites W2042263669 @default.
• W4311357718 cites W2044143372 @default.
• W4311357718 cites W2046674195 @default.
• W4311357718 cites W2047854495 @default.
• W4311357718 cites W2058787068 @default.
• W4311357718 cites W2065372326 @default.
• W4311357718 cites W2065509102 @default.
• W4311357718 cites W2069492714 @default.
• W4311357718 cites W2077682655 @default.
• W4311357718 cites W2078074336 @default.
• W4311357718 cites W2078753143 @default.
• W4311357718 cites W2080685259 @default.
• W4311357718 cites W2087777085 @default.
• W4311357718 cites W2090734611 @default.
• W4311357718 cites W2092660473 @default.
• W4311357718 cites W2095030312 @default.
• W4311357718 cites W2101510430 @default.
• W4311357718 cites W2103566186 @default.
• W4311357718 cites W2108325229 @default.
• W4311357718 cites W2116223045 @default.
• W4311357718 cites W2124033174 @default.
• W4311357718 cites W2133885246 @default.
• W4311357718 cites W2137564359 @default.
• W4311357718 cites W2140783672 @default.
• W4311357718 cites W2141538618 @default.
• W4311357718 cites W2142071180 @default.
• W4311357718 cites W2146752617 @default.
• W4311357718 cites W2153269424 @default.
• W4311357718 cites W2255281718 @default.
• W4311357718 cites W2405306801 @default.
• W4311357718 cites W2464336937 @default.
• W4311357718 cites W2483086400 @default.
• W4311357718 cites W2542851683 @default.
• W4311357718 cites W2552111517 @default.
• W4311357718 cites W2601743360 @default.
• W4311357718 cites W2621085537 @default.
• W4311357718 cites W2727815449 @default.
• W4311357718 cites W2747214860 @default.
• W4311357718 cites W2769523034 @default.
• W4311357718 cites W2769532020 @default.
• W4311357718 cites W2791015599 @default.
• W4311357718 cites W2890965800 @default.
• W4311357718 cites W2938565211 @default.
• W4311357718 cites W2950108090 @default.
• W4311357718 cites W2955844986 @default.
• W4311357718 cites W2973163219 @default.
• W4311357718 cites W2980604123 @default.
• W4311357718 cites W2985267845 @default.
• W4311357718 cites W3001989577 @default.
• W4311357718 cites W3038922946 @default.
• W4311357718 cites W3046810581 @default.
• W4311357718 cites W3081798949 @default.
• W4311357718 cites W3092217601 @default.
• W4311357718 cites W3102503591 @default.
• W4311357718 cites W3127600001 @default.
• W4311357718 cites W3175161321 @default.
• W4311357718 cites W3178592311 @default.
• W4311357718 cites W4220743971 @default.
• W4311357718 cites W4225152680 @default.
• W4311357718 cites W4229008930 @default.
• W4311357718 cites W4253355668 @default.
• W4311357718 cites W4282945867 @default.
• W4311357718 cites W4289347456 @default.
• W4311357718 cites W4296217399 @default.
• W4311357718 cites W595676579 @default.
• W4311357718 cites W990903207 @default.
• W4311357718 doi "https://doi.org/10.3390/e24121813" @default.
• W4311357718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36554218" @default.

• next