FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311365102> ?p ?o ?g. }

• W4311365102 abstract "Transcranial direct current stimulation (tDCS) is a technique that can noninvasively modulate neural states in a targeted brain region. As cerebellar activity levels are associated with upper limb motor improvement after stroke, the cerebellum is a plausible target of tDCS. However, the effect of tDCS remains unclear. Here, we designed a pilot study to assess: (1) the feasibility of a study that aims to examine the effects of cerebellar tDCS combined with an intensive rehabilitation approach based on the concept of constraint-induced movement therapy (CIMT) and (2) the preliminary outcome of the combined approach on upper limb motor function in patients with stroke in the chronic stage.This pilot study has a double-blind randomized controlled design. Twenty-four chronic stroke patients with mild to moderate levels of upper limb motor impairment will be randomly assigned to an active or sham tDCS group. The participants will receive 20 min of active or sham tDCS to the contralesional cerebellum at the commencement of 4 h of daily intensive training, repeatedly for 5 days per week for 2 weeks. The primary outcomes are recruitment, enrollment, protocol adherence, and retention rates and measures to evaluate the feasibility of the study. The secondary outcome is upper limb motor function which will be evaluated using the Action Research Arm Test, Fugl-Meyer Assessment, for the upper extremity and the Motor Activity Log. Additionally, neurophysiological and neuroanatomical assessments of the cerebellum will be performed using transcranial magnetic stimulation and magnetic resonance imaging. These assessments will be conducted before, at the middle, and after the 2-week intervention, and finally, 1 month after the intervention. Any adverse events that occur during the study will be recorded.Cerebellar tDCS combined with intensive upper limb training may increase the gains of motor improvement when compared to the sham condition. The present study should provide valuable evidence regarding the feasibility of the design and the efficacy of cerebellar tDCS for upper limb motor function in patients with stroke before a future large trial is conducted.This study has been registered at the Japan Registry of Clinical Trials ( jRCTs042200078 ). Registered 17 December 2020." @default.
• W4311365102 created "2022-12-25" @default.
• W4311365102 creator A5013118635 @default.
• W4311365102 creator A5019744904 @default.
• W4311365102 creator A5021324624 @default.
• W4311365102 creator A5030406846 @default.
• W4311365102 creator A5041954621 @default.
• W4311365102 creator A5059397647 @default.
• W4311365102 creator A5076580322 @default.
• W4311365102 date "2022-12-14" @default.
• W4311365102 modified "2023-09-26" @default.
• W4311365102 title "Effects of cerebellar transcranial direct current stimulation on upper limb motor function after stroke: study protocol for the pilot of a randomized controlled trial" @default.
• W4311365102 cites W1617736026 @default.
• W4311365102 cites W1695351344 @default.
• W4311365102 cites W1828273486 @default.
• W4311365102 cites W1847168837 @default.
• W4311365102 cites W1932009548 @default.
• W4311365102 cites W1965340069 @default.
• W4311365102 cites W1974590317 @default.
• W4311365102 cites W1980143688 @default.
• W4311365102 cites W1981786093 @default.
• W4311365102 cites W1981990510 @default.
• W4311365102 cites W1984426843 @default.
• W4311365102 cites W2008854521 @default.
• W4311365102 cites W2029611333 @default.
• W4311365102 cites W2044536862 @default.
• W4311365102 cites W2058161128 @default.
• W4311365102 cites W2062124861 @default.
• W4311365102 cites W2079124738 @default.
• W4311365102 cites W2079244518 @default.
• W4311365102 cites W2079890482 @default.
• W4311365102 cites W2080990968 @default.
• W4311365102 cites W2082435953 @default.
• W4311365102 cites W2085126485 @default.
• W4311365102 cites W2095116161 @default.
• W4311365102 cites W2097273459 @default.
• W4311365102 cites W2105145689 @default.
• W4311365102 cites W2107495673 @default.
• W4311365102 cites W2107536444 @default.
• W4311365102 cites W2117889222 @default.
• W4311365102 cites W2121234456 @default.
• W4311365102 cites W2126377447 @default.
• W4311365102 cites W2128704742 @default.
• W4311365102 cites W2134118125 @default.
• W4311365102 cites W2136361599 @default.
• W4311365102 cites W2137904825 @default.
• W4311365102 cites W2137916523 @default.
• W4311365102 cites W2138150447 @default.
• W4311365102 cites W2139049236 @default.
• W4311365102 cites W2140358254 @default.
• W4311365102 cites W2146660117 @default.
• W4311365102 cites W2147214889 @default.
• W4311365102 cites W2147518206 @default.
• W4311365102 cites W2148080316 @default.
• W4311365102 cites W2151989011 @default.
• W4311365102 cites W2156295356 @default.
• W4311365102 cites W2158985711 @default.
• W4311365102 cites W2163507898 @default.
• W4311365102 cites W2167311298 @default.
• W4311365102 cites W2168529864 @default.
• W4311365102 cites W2170182466 @default.
• W4311365102 cites W2170671331 @default.
• W4311365102 cites W2176659382 @default.
• W4311365102 cites W2238839018 @default.
• W4311365102 cites W2346795597 @default.
• W4311365102 cites W2357746748 @default.
• W4311365102 cites W2399618205 @default.
• W4311365102 cites W2530435296 @default.
• W4311365102 cites W2534656414 @default.
• W4311365102 cites W2539965696 @default.
• W4311365102 cites W2557310241 @default.
• W4311365102 cites W2588182016 @default.
• W4311365102 cites W2603257905 @default.
• W4311365102 cites W2754606804 @default.
• W4311365102 cites W2754616334 @default.
• W4311365102 cites W2766613848 @default.
• W4311365102 cites W2766851824 @default.
• W4311365102 cites W2769021531 @default.
• W4311365102 cites W2774286057 @default.
• W4311365102 cites W2883789151 @default.
• W4311365102 cites W2898419155 @default.
• W4311365102 cites W2909171213 @default.
• W4311365102 cites W2942162549 @default.
• W4311365102 cites W2944434778 @default.
• W4311365102 cites W2948144317 @default.
• W4311365102 cites W2981839458 @default.
• W4311365102 cites W2988645757 @default.
• W4311365102 cites W2988820558 @default.
• W4311365102 cites W2996652152 @default.
• W4311365102 cites W3017329765 @default.
• W4311365102 cites W3019602927 @default.
• W4311365102 doi "https://doi.org/10.1186/s40814-022-01223-9" @default.
• W4311365102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36517911" @default.
• W4311365102 hasPublicationYear "2022" @default.
• W4311365102 type Work @default.
• W4311365102 citedByCount "0" @default.
• W4311365102 crossrefType "journal-article" @default.
• W4311365102 hasAuthorship W4311365102A5013118635 @default.
• W4311365102 hasAuthorship W4311365102A5019744904 @default.
• W4311365102 hasAuthorship W4311365102A5021324624 @default.

• next