FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311442076> ?p ?o ?g. }

• W4311442076 endingPage "2296" @default.
• W4311442076 startingPage "2287" @default.
• W4311442076 abstract "Abstract The prognostic relevance of diagnosis to treatment interval (DTI) in patients with newly diagnosed mantle cell lymphoma (MCL) is unknown. Hence, we sought to evaluate the impact of DTI on outcomes in MCL using 3 large datasets (1) the University of Iowa/Mayo Clinic Specialized Program of Research Excellence Molecular Epidemiology Resource, (2) patients enrolled in the ALL Age Asthma Cohort/CALGB 50403, and (3) a multisitecohort of patients with MCL. Patients were a priori divided into 2 groups, 0 to 14 days (short DTI) and 15 to 60 days (long DTI). The patients in whom observation was deemed appropriate were excluded. One thousand ninety-seven patients newly diagnosed with MCL and available DTI were included in the study. The majority (73%) had long DTI (n=797). Patients with short DTI had worse eastern cooperative oncology group performance status (ECOG PS ≥2), higher lactate dehydrogenase, bone marrow involvement, more frequent B symptoms, higher MCL International Prognostic Index (MIPI ≥6.2), and were less likely to receive intensive induction therapy than long DTI group. The median progression-free survival (2.5 years vs 4.8 years, p&lt;0.0001) and overall survival (7.8 years vs. 11.8 years, p&lt;0.0001) were significantly inferior in the short DTI group than the long DTI cohort and remained significant for progression-free survival and overall survival in multivariable analysis. We show that the DTI is an important prognostic factor in patients newly diagnosed with MCL and is strongly associated with adverse clinical factors and poor outcomes. DTI should be reported in all the patients newly diagnosed with MCL who are enrolling in clinical trials and steps must be taken to ensure selection bias is avoided." @default.
• W4311442076 created "2022-12-26" @default.
• W4311442076 creator A5000227859 @default.
• W4311442076 creator A5005446802 @default.
• W4311442076 creator A5006235077 @default.
• W4311442076 creator A5007477825 @default.
• W4311442076 creator A5009486064 @default.
• W4311442076 creator A5011030256 @default.
• W4311442076 creator A5017559837 @default.
• W4311442076 creator A5019666650 @default.
• W4311442076 creator A5024389256 @default.
• W4311442076 creator A5025688165 @default.
• W4311442076 creator A5027080346 @default.
• W4311442076 creator A5027975872 @default.
• W4311442076 creator A5037882455 @default.
• W4311442076 creator A5039776999 @default.
• W4311442076 creator A5043541884 @default.
• W4311442076 creator A5049293438 @default.
• W4311442076 creator A5051862003 @default.
• W4311442076 creator A5056946123 @default.
• W4311442076 creator A5059417970 @default.
• W4311442076 creator A5060718239 @default.
• W4311442076 creator A5064125880 @default.
• W4311442076 creator A5067489954 @default.
• W4311442076 creator A5067633124 @default.
• W4311442076 creator A5069054551 @default.
• W4311442076 creator A5069393942 @default.
• W4311442076 creator A5069849982 @default.
• W4311442076 creator A5070252326 @default.
• W4311442076 creator A5071201232 @default.
• W4311442076 creator A5074766331 @default.
• W4311442076 creator A5075085884 @default.
• W4311442076 creator A5076621021 @default.
• W4311442076 creator A5082892912 @default.
• W4311442076 creator A5083450833 @default.
• W4311442076 creator A5085565650 @default.
• W4311442076 creator A5087020208 @default.
• W4311442076 creator A5090406453 @default.
• W4311442076 date "2023-05-24" @default.
• W4311442076 modified "2023-10-07" @default.
• W4311442076 title "Impact of diagnosis to treatment interval in patients with newly diagnosed mantle cell lymphoma" @default.
• W4311442076 cites W1966855461 @default.
• W4311442076 cites W1974788142 @default.
• W4311442076 cites W1995920800 @default.
• W4311442076 cites W2001178238 @default.
• W4311442076 cites W2043275534 @default.
• W4311442076 cites W2130669641 @default.
• W4311442076 cites W2289178667 @default.
• W4311442076 cites W2346002269 @default.
• W4311442076 cites W2609037652 @default.
• W4311442076 cites W2726940470 @default.
• W4311442076 cites W2749289906 @default.
• W4311442076 cites W2749791749 @default.
• W4311442076 cites W2789664398 @default.
• W4311442076 cites W2800428352 @default.
• W4311442076 cites W2801979411 @default.
• W4311442076 cites W3011341107 @default.
• W4311442076 cites W3158232058 @default.
• W4311442076 cites W3160622871 @default.
• W4311442076 cites W3200845029 @default.
• W4311442076 doi "https://doi.org/10.1182/bloodadvances.2022009225" @default.
• W4311442076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36516079" @default.
• W4311442076 hasPublicationYear "2023" @default.
• W4311442076 type Work @default.
• W4311442076 citedByCount "2" @default.
• W4311442076 countsByYear W43114420762023 @default.
• W4311442076 crossrefType "journal-article" @default.
• W4311442076 hasAuthorship W4311442076A5000227859 @default.
• W4311442076 hasAuthorship W4311442076A5005446802 @default.
• W4311442076 hasAuthorship W4311442076A5006235077 @default.
• W4311442076 hasAuthorship W4311442076A5007477825 @default.
• W4311442076 hasAuthorship W4311442076A5009486064 @default.
• W4311442076 hasAuthorship W4311442076A5011030256 @default.
• W4311442076 hasAuthorship W4311442076A5017559837 @default.
• W4311442076 hasAuthorship W4311442076A5019666650 @default.
• W4311442076 hasAuthorship W4311442076A5024389256 @default.
• W4311442076 hasAuthorship W4311442076A5025688165 @default.
• W4311442076 hasAuthorship W4311442076A5027080346 @default.
• W4311442076 hasAuthorship W4311442076A5027975872 @default.
• W4311442076 hasAuthorship W4311442076A5037882455 @default.
• W4311442076 hasAuthorship W4311442076A5039776999 @default.
• W4311442076 hasAuthorship W4311442076A5043541884 @default.
• W4311442076 hasAuthorship W4311442076A5049293438 @default.
• W4311442076 hasAuthorship W4311442076A5051862003 @default.
• W4311442076 hasAuthorship W4311442076A5056946123 @default.
• W4311442076 hasAuthorship W4311442076A5059417970 @default.
• W4311442076 hasAuthorship W4311442076A5060718239 @default.
• W4311442076 hasAuthorship W4311442076A5064125880 @default.
• W4311442076 hasAuthorship W4311442076A5067489954 @default.
• W4311442076 hasAuthorship W4311442076A5067633124 @default.
• W4311442076 hasAuthorship W4311442076A5069054551 @default.
• W4311442076 hasAuthorship W4311442076A5069393942 @default.
• W4311442076 hasAuthorship W4311442076A5069849982 @default.
• W4311442076 hasAuthorship W4311442076A5070252326 @default.
• W4311442076 hasAuthorship W4311442076A5071201232 @default.
• W4311442076 hasAuthorship W4311442076A5074766331 @default.
• W4311442076 hasAuthorship W4311442076A5075085884 @default.
• W4311442076 hasAuthorship W4311442076A5076621021 @default.

• next