FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311452040> ?p ?o ?g. }

• W4311452040 endingPage "114440" @default.
• W4311452040 startingPage "114440" @default.
• W4311452040 abstract "Globally, microplastics (MPs) are highly prevalent, especially in coastal areas. Unfortunately, golden pompano as a major marine fish in China is typically raised in floating marine cages near coasts, facing these MPs sources. However, toxicological studies on Golden Pompano which farm in coastal areas and face actual microplastic exposure are rare. Therefore, golden pompano were exposed to 10.0 μg/L, 100.0 μg/L, and 1000.0 μg/L polystyrene MPs (PS-MPs) for 14 days to study the potential impact of the microplastics on the Golden Pompano. Fish show slowed growth after 14 days of exposure. Histopathology shows irregular shaped nuclei and nuclear and cytoplasmic vacuolation traits in liver. Oxidative stress-related enzyme activity and gene expression data show that oxidative damage occurs in the high-concentrations (100.0 μg/L and 1000.0 μg/L) of PS-MPs exposures. Up-regulation of Grp78, Xbp-1, Eif-2α and chop gene expression indicates the occurrence of endoplasmic reticulum stress, and the western blot results also confirmed this. Severe oxidative stress also caused ERS, which ultimately increased BAX/Bcl-2 ratios and induces apoptosis. Furthermore, up-regulated anaerobic respiration, altered lipid metabolism, and immune disturbance were exhibited during PS-MPs stress. Therefore, oxidative stress appeared to be the main toxicity issue caused by MPs, while ERS-mediated apoptosis, metabolic alterations, and immune responses were induced by this stress. Notably, endoplasmic reticulum stress and apoptosis are a self-protective mechanism, which may be an intermediate link in the toxicity of microplastics. This study highlights the role of endoplasmic reticulum stress in MPs toxicology and assesses the adverse effects of microplastics on Golden Pompano." @default.
• W4311452040 created "2022-12-26" @default.
• W4311452040 creator A5000020659 @default.
• W4311452040 creator A5007909496 @default.
• W4311452040 creator A5017303956 @default.
• W4311452040 creator A5023061868 @default.
• W4311452040 creator A5024525336 @default.
• W4311452040 creator A5078659297 @default.
• W4311452040 creator A5078909773 @default.
• W4311452040 creator A5080662768 @default.
• W4311452040 date "2023-01-01" @default.
• W4311452040 modified "2023-10-01" @default.
• W4311452040 title "The involvement of oxidative stress mediated endoplasmic reticulum pathway in apoptosis of Golden Pompano (Trachinotus blochii) liver under PS-MPs stress" @default.
• W4311452040 cites W2214858649 @default.
• W4311452040 cites W2295281563 @default.
• W4311452040 cites W2430007335 @default.
• W4311452040 cites W2914833654 @default.
• W4311452040 cites W2922098032 @default.
• W4311452040 cites W2948005638 @default.
• W4311452040 cites W2951940575 @default.
• W4311452040 cites W2977857977 @default.
• W4311452040 cites W2999690316 @default.
• W4311452040 cites W3005399349 @default.
• W4311452040 cites W3005753228 @default.
• W4311452040 cites W3036656245 @default.
• W4311452040 cites W3039418677 @default.
• W4311452040 cites W3081997571 @default.
• W4311452040 cites W3092004091 @default.
• W4311452040 cites W3092009047 @default.
• W4311452040 cites W3093710724 @default.
• W4311452040 cites W3097928199 @default.
• W4311452040 cites W3099817120 @default.
• W4311452040 cites W3110537276 @default.
• W4311452040 cites W3117360044 @default.
• W4311452040 cites W3122180539 @default.
• W4311452040 cites W3128346971 @default.
• W4311452040 cites W3129180320 @default.
• W4311452040 cites W3132464854 @default.
• W4311452040 cites W3132603121 @default.
• W4311452040 cites W3138744423 @default.
• W4311452040 cites W3156080874 @default.
• W4311452040 cites W3158150483 @default.
• W4311452040 cites W3170030948 @default.
• W4311452040 cites W3182226127 @default.
• W4311452040 cites W3212209229 @default.
• W4311452040 cites W4200592541 @default.
• W4311452040 cites W4205540002 @default.
• W4311452040 cites W4206948924 @default.
• W4311452040 cites W4225279684 @default.
• W4311452040 doi "https://doi.org/10.1016/j.ecoenv.2022.114440" @default.
• W4311452040 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36525944" @default.
• W4311452040 hasPublicationYear "2023" @default.
• W4311452040 type Work @default.
• W4311452040 citedByCount "3" @default.
• W4311452040 countsByYear W43114520402023 @default.
• W4311452040 crossrefType "journal-article" @default.
• W4311452040 hasAuthorship W4311452040A5000020659 @default.
• W4311452040 hasAuthorship W4311452040A5007909496 @default.
• W4311452040 hasAuthorship W4311452040A5017303956 @default.
• W4311452040 hasAuthorship W4311452040A5023061868 @default.
• W4311452040 hasAuthorship W4311452040A5024525336 @default.
• W4311452040 hasAuthorship W4311452040A5078659297 @default.
• W4311452040 hasAuthorship W4311452040A5078909773 @default.
• W4311452040 hasAuthorship W4311452040A5080662768 @default.
• W4311452040 hasBestOaLocation W43114520401 @default.
• W4311452040 hasConcept C126322002 @default.
• W4311452040 hasConcept C139447449 @default.
• W4311452040 hasConcept C158617107 @default.
• W4311452040 hasConcept C16685009 @default.
• W4311452040 hasConcept C18903297 @default.
• W4311452040 hasConcept C190283241 @default.
• W4311452040 hasConcept C2776151105 @default.
• W4311452040 hasConcept C2780401329 @default.
• W4311452040 hasConcept C29730261 @default.
• W4311452040 hasConcept C55493867 @default.
• W4311452040 hasConcept C71924100 @default.
• W4311452040 hasConcept C86803240 @default.
• W4311452040 hasConcept C95444343 @default.
• W4311452040 hasConceptScore W4311452040C126322002 @default.
• W4311452040 hasConceptScore W4311452040C139447449 @default.
• W4311452040 hasConceptScore W4311452040C158617107 @default.
• W4311452040 hasConceptScore W4311452040C16685009 @default.
• W4311452040 hasConceptScore W4311452040C18903297 @default.
• W4311452040 hasConceptScore W4311452040C190283241 @default.
• W4311452040 hasConceptScore W4311452040C2776151105 @default.
• W4311452040 hasConceptScore W4311452040C2780401329 @default.
• W4311452040 hasConceptScore W4311452040C29730261 @default.
• W4311452040 hasConceptScore W4311452040C55493867 @default.
• W4311452040 hasConceptScore W4311452040C71924100 @default.
• W4311452040 hasConceptScore W4311452040C86803240 @default.
• W4311452040 hasConceptScore W4311452040C95444343 @default.
• W4311452040 hasLocation W43114520401 @default.
• W4311452040 hasLocation W43114520402 @default.
• W4311452040 hasOpenAccess W4311452040 @default.
• W4311452040 hasPrimaryLocation W43114520401 @default.
• W4311452040 hasRelatedWork W1996066332 @default.
• W4311452040 hasRelatedWork W2003338675 @default.
• W4311452040 hasRelatedWork W2072667779 @default.

• next