Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311455296> ?p ?o ?g. }
- W4311455296 endingPage "22" @default.
- W4311455296 startingPage "1" @default.
- W4311455296 abstract "Pyroptosis is a kind of programmed cell death related to inflammation, which is closely related to cancer. The goal of this study is to establish and verify pyroptosis-related gene signature to predict the prognosis of patients with bladder cancer (BLCA) and explore its relationship with immunity. Somatic mutation, copy number variation, correlation, and expression of 33 pyroptosis-related genes were evaluated based on The Cancer Genome Atlas (TCGA) database. BLCA cases were divided into two clusters by consistent clustering and found that pyroptosis-related genes were related to the overall survival (OS) of BLCA. The least absolute shrinkage and selection operator (LASSO) Cox regression was used to construct the signature (including 7 pyroptosis-realated genes). Survival analysis curve and receiver operating characteristic curve (ROC) showed that this signature could predict the prognosis of BLCA patients. Univariate and multivariate Cox regression analysis showed the independent prognostic value of this model. Immune infiltration analysis showed that the six types of immune cells have significantly different infiltrations. The effect of immunotherapy is better in the low-risk group. In summary, our effort indicated the potential role of pyroptosis-related genes in BLCA and provided new perspectives on the prognosis of BLCA and new ideas for immunotherapy." @default.
- W4311455296 created "2022-12-26" @default.
- W4311455296 creator A5013116262 @default.
- W4311455296 creator A5020442380 @default.
- W4311455296 creator A5042083904 @default.
- W4311455296 creator A5069571261 @default.
- W4311455296 date "2022-12-14" @default.
- W4311455296 modified "2023-10-18" @default.
- W4311455296 title "Construction of Pyroptosis-Related Prognostic and Immune Infiltration Signature in Bladder Cancer" @default.
- W4311455296 cites W1167534253 @default.
- W4311455296 cites W1524712950 @default.
- W4311455296 cites W1864325817 @default.
- W4311455296 cites W1916083974 @default.
- W4311455296 cites W1985970823 @default.
- W4311455296 cites W2005410446 @default.
- W4311455296 cites W2007389188 @default.
- W4311455296 cites W2018983895 @default.
- W4311455296 cites W2021175628 @default.
- W4311455296 cites W2024156622 @default.
- W4311455296 cites W2030720027 @default.
- W4311455296 cites W2042699075 @default.
- W4311455296 cites W2065202184 @default.
- W4311455296 cites W2079501367 @default.
- W4311455296 cites W2084708403 @default.
- W4311455296 cites W2118731963 @default.
- W4311455296 cites W2126292500 @default.
- W4311455296 cites W2139781585 @default.
- W4311455296 cites W2462773201 @default.
- W4311455296 cites W2560541542 @default.
- W4311455296 cites W2575182211 @default.
- W4311455296 cites W2580623258 @default.
- W4311455296 cites W2608687752 @default.
- W4311455296 cites W2610420640 @default.
- W4311455296 cites W2749934938 @default.
- W4311455296 cites W2753155927 @default.
- W4311455296 cites W2767993459 @default.
- W4311455296 cites W2783806340 @default.
- W4311455296 cites W2788640168 @default.
- W4311455296 cites W2794672909 @default.
- W4311455296 cites W2807110328 @default.
- W4311455296 cites W2883341207 @default.
- W4311455296 cites W2885788384 @default.
- W4311455296 cites W2889646458 @default.
- W4311455296 cites W2897923935 @default.
- W4311455296 cites W2918426281 @default.
- W4311455296 cites W2951509935 @default.
- W4311455296 cites W2964811008 @default.
- W4311455296 cites W2965406966 @default.
- W4311455296 cites W2972758365 @default.
- W4311455296 cites W2982897711 @default.
- W4311455296 cites W3008954267 @default.
- W4311455296 cites W3012485477 @default.
- W4311455296 cites W3013123339 @default.
- W4311455296 cites W3016811071 @default.
- W4311455296 cites W3017229457 @default.
- W4311455296 cites W3042737205 @default.
- W4311455296 cites W3048625141 @default.
- W4311455296 cites W3082328907 @default.
- W4311455296 cites W3144571741 @default.
- W4311455296 cites W3171550932 @default.
- W4311455296 cites W3175095680 @default.
- W4311455296 cites W4211115520 @default.
- W4311455296 cites W4224990981 @default.
- W4311455296 cites W4230549279 @default.
- W4311455296 doi "https://doi.org/10.1155/2022/6429993" @default.
- W4311455296 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36569221" @default.
- W4311455296 hasPublicationYear "2022" @default.
- W4311455296 type Work @default.
- W4311455296 citedByCount "1" @default.
- W4311455296 countsByYear W43114552962023 @default.
- W4311455296 crossrefType "journal-article" @default.
- W4311455296 hasAuthorship W4311455296A5013116262 @default.
- W4311455296 hasAuthorship W4311455296A5020442380 @default.
- W4311455296 hasAuthorship W4311455296A5042083904 @default.
- W4311455296 hasAuthorship W4311455296A5069571261 @default.
- W4311455296 hasBestOaLocation W43114552961 @default.
- W4311455296 hasConcept C104317684 @default.
- W4311455296 hasConcept C10515644 @default.
- W4311455296 hasConcept C121608353 @default.
- W4311455296 hasConcept C126322002 @default.
- W4311455296 hasConcept C143998085 @default.
- W4311455296 hasConcept C150194340 @default.
- W4311455296 hasConcept C17172800 @default.
- W4311455296 hasConcept C190283241 @default.
- W4311455296 hasConcept C203014093 @default.
- W4311455296 hasConcept C2777701055 @default.
- W4311455296 hasConcept C2779733811 @default.
- W4311455296 hasConcept C2780352672 @default.
- W4311455296 hasConcept C31573885 @default.
- W4311455296 hasConcept C502942594 @default.
- W4311455296 hasConcept C50382708 @default.
- W4311455296 hasConcept C54355233 @default.
- W4311455296 hasConcept C58471807 @default.
- W4311455296 hasConcept C71924100 @default.
- W4311455296 hasConcept C86803240 @default.
- W4311455296 hasConcept C8891405 @default.
- W4311455296 hasConceptScore W4311455296C104317684 @default.
- W4311455296 hasConceptScore W4311455296C10515644 @default.