Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311455570> ?p ?o ?g. }
- W4311455570 endingPage "418" @default.
- W4311455570 startingPage "407" @default.
- W4311455570 abstract "Abstract Background The poor outcome of patients with lung squamous cell carcinoma (LUSC) highlights the importance of the identification of novel effective prognostic markers and therapeutic targets. Long noncoding RNAs (lncRNAs) have generally been considered to serve important roles in tumorigenesis and the development of various types of cancer, including LUSC. Methods Here, we aimed to investigate the role of LINC02323 in LUSC and its potential mechanisms by performing comprehensive bioinformatic analyses. Results LINC02323 was elevated and positively associated with unfavorable prognosis of LUSC patients. LINC02323 exerted oncogenic function by competitively binding to miR‐1343‐3p and miR‐6783‐3p, thereby upregulating L1CAM expression. Indeed, we also determined that LINC02323 could interact with the RNA‐binding protein DDX3X, which regulates various stages of RNA expression and processing. Conclusion Taken together, we identified that LINC02323 and its indirect target L1CAM can act as novel biomarkers for determining the prognosis of patients with LUSC and thus deserves further study." @default.
- W4311455570 created "2022-12-26" @default.
- W4311455570 creator A5000298062 @default.
- W4311455570 creator A5055622227 @default.
- W4311455570 creator A5061223156 @default.
- W4311455570 creator A5062968118 @default.
- W4311455570 creator A5065456698 @default.
- W4311455570 creator A5069818013 @default.
- W4311455570 creator A5074411104 @default.
- W4311455570 creator A5088705104 @default.
- W4311455570 date "2022-12-14" @default.
- W4311455570 modified "2023-10-10" @default.
- W4311455570 title "<scp><i>LINC02323</i></scp> facilitates development of lung squamous cell carcinoma by <scp>miRNA</scp> sponge and <scp>RBP</scp> dysregulation and links to poor prognosis" @default.
- W4311455570 cites W1972333858 @default.
- W4311455570 cites W2028342121 @default.
- W4311455570 cites W2416190981 @default.
- W4311455570 cites W2772479564 @default.
- W4311455570 cites W2784623697 @default.
- W4311455570 cites W2808862148 @default.
- W4311455570 cites W2901415421 @default.
- W4311455570 cites W2954754264 @default.
- W4311455570 cites W3003235501 @default.
- W4311455570 cites W3041475396 @default.
- W4311455570 cites W3048896255 @default.
- W4311455570 cites W3082618154 @default.
- W4311455570 cites W3107506298 @default.
- W4311455570 cites W3128646645 @default.
- W4311455570 cites W3129774208 @default.
- W4311455570 cites W3169980170 @default.
- W4311455570 cites W3206072554 @default.
- W4311455570 cites W4220726129 @default.
- W4311455570 cites W4220922528 @default.
- W4311455570 cites W4224051468 @default.
- W4311455570 cites W4229054491 @default.
- W4311455570 cites W4281674710 @default.
- W4311455570 cites W4285307704 @default.
- W4311455570 cites W4286461834 @default.
- W4311455570 cites W4290465932 @default.
- W4311455570 cites W4292448949 @default.
- W4311455570 cites W4292679428 @default.
- W4311455570 cites W4292683652 @default.
- W4311455570 cites W4293527347 @default.
- W4311455570 cites W4293776444 @default.
- W4311455570 cites W4295078661 @default.
- W4311455570 cites W4296252916 @default.
- W4311455570 cites W4296935208 @default.
- W4311455570 cites W4298119357 @default.
- W4311455570 cites W4311455570 @default.
- W4311455570 cites W925548801 @default.
- W4311455570 doi "https://doi.org/10.1111/1759-7714.14760" @default.
- W4311455570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36516959" @default.
- W4311455570 hasPublicationYear "2022" @default.
- W4311455570 type Work @default.
- W4311455570 citedByCount "3" @default.
- W4311455570 countsByYear W43114555702022 @default.
- W4311455570 countsByYear W43114555702023 @default.
- W4311455570 crossrefType "journal-article" @default.
- W4311455570 hasAuthorship W4311455570A5000298062 @default.
- W4311455570 hasAuthorship W4311455570A5055622227 @default.
- W4311455570 hasAuthorship W4311455570A5061223156 @default.
- W4311455570 hasAuthorship W4311455570A5062968118 @default.
- W4311455570 hasAuthorship W4311455570A5065456698 @default.
- W4311455570 hasAuthorship W4311455570A5069818013 @default.
- W4311455570 hasAuthorship W4311455570A5074411104 @default.
- W4311455570 hasAuthorship W4311455570A5088705104 @default.
- W4311455570 hasBestOaLocation W43114555701 @default.
- W4311455570 hasConcept C104317684 @default.
- W4311455570 hasConcept C121608353 @default.
- W4311455570 hasConcept C126322002 @default.
- W4311455570 hasConcept C145059251 @default.
- W4311455570 hasConcept C2776256026 @default.
- W4311455570 hasConcept C502942594 @default.
- W4311455570 hasConcept C54355233 @default.
- W4311455570 hasConcept C555283112 @default.
- W4311455570 hasConcept C60644358 @default.
- W4311455570 hasConcept C71924100 @default.
- W4311455570 hasConcept C86803240 @default.
- W4311455570 hasConceptScore W4311455570C104317684 @default.
- W4311455570 hasConceptScore W4311455570C121608353 @default.
- W4311455570 hasConceptScore W4311455570C126322002 @default.
- W4311455570 hasConceptScore W4311455570C145059251 @default.
- W4311455570 hasConceptScore W4311455570C2776256026 @default.
- W4311455570 hasConceptScore W4311455570C502942594 @default.
- W4311455570 hasConceptScore W4311455570C54355233 @default.
- W4311455570 hasConceptScore W4311455570C555283112 @default.
- W4311455570 hasConceptScore W4311455570C60644358 @default.
- W4311455570 hasConceptScore W4311455570C71924100 @default.
- W4311455570 hasConceptScore W4311455570C86803240 @default.
- W4311455570 hasFunder F4320322795 @default.
- W4311455570 hasIssue "4" @default.
- W4311455570 hasLocation W43114555701 @default.
- W4311455570 hasLocation W43114555702 @default.
- W4311455570 hasLocation W43114555703 @default.
- W4311455570 hasOpenAccess W4311455570 @default.
- W4311455570 hasPrimaryLocation W43114555701 @default.
- W4311455570 hasRelatedWork W1544124033 @default.
- W4311455570 hasRelatedWork W1973739765 @default.
- W4311455570 hasRelatedWork W2075207018 @default.