Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311463239> ?p ?o ?g. }
- W4311463239 endingPage "17979" @default.
- W4311463239 startingPage "17972" @default.
- W4311463239 abstract "Achieving accurate measurements of G-quadruplexes (G4s), especially the characterization of their complicated non-covalent interactions with various components (such as metal ions and ligands) under physiological conditions, is of fundamental significance in unveiling their biological roles and developing antitumor drugs. By employing a nanopore ion emitter (∼30 nm), we demonstrated for the first time that G4 ions, which are free of non-specific adduction and meanwhile maintaining their pre-existing specific bindings with metal ions or ligands, can be directly liberated from common biochemical buffers (consisting of concentrated non-volatile salts of >150 mM) for mass spectrometric examination. Notably, the intermediate complexes of G4s with mixed di-cation coordination formed during the Na+/K+ exchange were successfully observed by mass spectrometry, whose structures were also revealed by the reconstructed circular dichroism spectra. We believe the nanopore-based ion emitters have built a solid bridge between native G4s in aqueous buffers and their accurate stoichiometries obtained by mass spectrometric examination." @default.
- W4311463239 created "2022-12-26" @default.
- W4311463239 creator A5040476342 @default.
- W4311463239 creator A5050812850 @default.
- W4311463239 creator A5078075455 @default.
- W4311463239 creator A5078530516 @default.
- W4311463239 date "2022-12-14" @default.
- W4311463239 modified "2023-10-16" @default.
- W4311463239 title "Nanopore Liberates G-Quadruplexes from Biochemical Buffers for Accurate Mass Spectrometric Examination" @default.
- W4311463239 cites W1959626991 @default.
- W4311463239 cites W1966306581 @default.
- W4311463239 cites W1980513386 @default.
- W4311463239 cites W1981553228 @default.
- W4311463239 cites W1984760060 @default.
- W4311463239 cites W2007812774 @default.
- W4311463239 cites W2010999047 @default.
- W4311463239 cites W2026370504 @default.
- W4311463239 cites W2036400318 @default.
- W4311463239 cites W2039241171 @default.
- W4311463239 cites W2062724831 @default.
- W4311463239 cites W2067519806 @default.
- W4311463239 cites W2074615820 @default.
- W4311463239 cites W2081781483 @default.
- W4311463239 cites W2102362408 @default.
- W4311463239 cites W2107744687 @default.
- W4311463239 cites W2172060739 @default.
- W4311463239 cites W2292828264 @default.
- W4311463239 cites W2320936920 @default.
- W4311463239 cites W2327376952 @default.
- W4311463239 cites W2332530234 @default.
- W4311463239 cites W2410310292 @default.
- W4311463239 cites W2482357372 @default.
- W4311463239 cites W2521876591 @default.
- W4311463239 cites W2537246643 @default.
- W4311463239 cites W2571772761 @default.
- W4311463239 cites W2586632373 @default.
- W4311463239 cites W2612060709 @default.
- W4311463239 cites W2616627373 @default.
- W4311463239 cites W2623831325 @default.
- W4311463239 cites W2744839050 @default.
- W4311463239 cites W2751110354 @default.
- W4311463239 cites W2792386469 @default.
- W4311463239 cites W2898398639 @default.
- W4311463239 cites W2910553840 @default.
- W4311463239 cites W2910890866 @default.
- W4311463239 cites W2942578733 @default.
- W4311463239 cites W2966334511 @default.
- W4311463239 cites W3017349264 @default.
- W4311463239 cites W3100844675 @default.
- W4311463239 cites W3128212187 @default.
- W4311463239 cites W3133719327 @default.
- W4311463239 cites W3211821110 @default.
- W4311463239 cites W4210736569 @default.
- W4311463239 cites W4225337620 @default.
- W4311463239 cites W4252958962 @default.
- W4311463239 cites W4255306538 @default.
- W4311463239 cites W4283835623 @default.
- W4311463239 cites W4376453542 @default.
- W4311463239 doi "https://doi.org/10.1021/acs.analchem.2c04099" @default.
- W4311463239 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36515943" @default.
- W4311463239 hasPublicationYear "2022" @default.
- W4311463239 type Work @default.
- W4311463239 citedByCount "1" @default.
- W4311463239 crossrefType "journal-article" @default.
- W4311463239 hasAuthorship W4311463239A5040476342 @default.
- W4311463239 hasAuthorship W4311463239A5050812850 @default.
- W4311463239 hasAuthorship W4311463239A5078075455 @default.
- W4311463239 hasAuthorship W4311463239A5078530516 @default.
- W4311463239 hasConcept C113196181 @default.
- W4311463239 hasConcept C141795571 @default.
- W4311463239 hasConcept C144082473 @default.
- W4311463239 hasConcept C145148216 @default.
- W4311463239 hasConcept C147789679 @default.
- W4311463239 hasConcept C162356407 @default.
- W4311463239 hasConcept C171250308 @default.
- W4311463239 hasConcept C178790620 @default.
- W4311463239 hasConcept C180577832 @default.
- W4311463239 hasConcept C184651966 @default.
- W4311463239 hasConcept C185592680 @default.
- W4311463239 hasConcept C192562407 @default.
- W4311463239 hasConcept C199164860 @default.
- W4311463239 hasConcept C21951064 @default.
- W4311463239 hasConcept C2780841128 @default.
- W4311463239 hasConcept C31827203 @default.
- W4311463239 hasConcept C43617362 @default.
- W4311463239 hasConcept C544153396 @default.
- W4311463239 hasConcept C552990157 @default.
- W4311463239 hasConcept C55493867 @default.
- W4311463239 hasConcept C83762044 @default.
- W4311463239 hasConceptScore W4311463239C113196181 @default.
- W4311463239 hasConceptScore W4311463239C141795571 @default.
- W4311463239 hasConceptScore W4311463239C144082473 @default.
- W4311463239 hasConceptScore W4311463239C145148216 @default.
- W4311463239 hasConceptScore W4311463239C147789679 @default.
- W4311463239 hasConceptScore W4311463239C162356407 @default.
- W4311463239 hasConceptScore W4311463239C171250308 @default.
- W4311463239 hasConceptScore W4311463239C178790620 @default.
- W4311463239 hasConceptScore W4311463239C180577832 @default.