FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311472825> ?p ?o ?g. }

• W4311472825 endingPage "285" @default.
• W4311472825 startingPage "281" @default.
• W4311472825 abstract "Background: Methamphetamine (MA) use is associated with sexual risk behavior as well as systemic and mucosal inflammation, suggesting parallel biological and behavioral mechanisms of HIV transmission among men who have sex with men (MSM) who use MA. Data evaluating the combined biological effects of MA use with concomitant rectal gonococcal and/or chlamydial (GC/CT) infection on inflammation are limited. Setting: Secondary analysis of stored rectal and plasma specimens from 100 MSM participating in an NIDA-funded longitudinal cohort in Los Angeles, CA. Methods: This cross-sectional analysis evaluated systemic and rectal inflammatory markers under 2 conditions: (1) recent MA use (by urine drug screen) and (2) rectal GC/CT infection. We evaluated 50 participants with recent MA use (25 with and 25 without rectal GC/CT) and 50 MSM without MA use (25 with and 25 without rectal GC/CT). Log-transformed plasma and rectal immune markers were regressed on MA exposure and rectal GC/CT, controlling for HIV status and age. Results: Median age was 32 (range 19–45) years, and 58% of participants were living with HIV. Plasma tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-8, IL-1ß, and rectal IL-6 were associated with rectal GC/CT and MA use, independent of HIV status. Higher levels of rectal TNF-α, IL-1ß, and IL-17a were associated with rectal GC/CT. Conclusions: Systemic and rectal inflammation was positively associated with rectal GC/CT and MA use. Condomless sex in the setting of GC/CT- and MA-induced immune activation may provide a basis for synergistic biobehavioral mechanisms that promote HIV/STI transmission among MSM who use MA." @default.
• W4311472825 created "2022-12-26" @default.
• W4311472825 creator A5000828542 @default.
• W4311472825 creator A5010391847 @default.
• W4311472825 creator A5010665253 @default.
• W4311472825 creator A5018816959 @default.
• W4311472825 creator A5025092594 @default.
• W4311472825 creator A5061940210 @default.
• W4311472825 date "2023-04-01" @default.
• W4311472825 modified "2023-10-16" @default.
• W4311472825 title "Brief Report: Impact of Methamphetamine Use and Rectal STIs on Systemic and Rectal Mucosal Inflammation" @default.
• W4311472825 cites W1597426933 @default.
• W4311472825 cites W1983183505 @default.
• W4311472825 cites W2003104614 @default.
• W4311472825 cites W2030845393 @default.
• W4311472825 cites W2031183059 @default.
• W4311472825 cites W2102168760 @default.
• W4311472825 cites W2116490394 @default.
• W4311472825 cites W2118545611 @default.
• W4311472825 cites W2122483069 @default.
• W4311472825 cites W2139463883 @default.
• W4311472825 cites W2140627676 @default.
• W4311472825 cites W2151662515 @default.
• W4311472825 cites W2163715260 @default.
• W4311472825 cites W2166192929 @default.
• W4311472825 cites W2171523916 @default.
• W4311472825 cites W2329156461 @default.
• W4311472825 cites W2360972905 @default.
• W4311472825 cites W2403122145 @default.
• W4311472825 cites W2550265388 @default.
• W4311472825 cites W2555744616 @default.
• W4311472825 cites W2607267328 @default.
• W4311472825 cites W2622767954 @default.
• W4311472825 cites W2789615509 @default.
• W4311472825 cites W2791198856 @default.
• W4311472825 cites W2791601054 @default.
• W4311472825 cites W2796375804 @default.
• W4311472825 cites W288437537 @default.
• W4311472825 cites W2889283632 @default.
• W4311472825 cites W2890099464 @default.
• W4311472825 cites W2902837410 @default.
• W4311472825 cites W2903424067 @default.
• W4311472825 cites W2938545599 @default.
• W4311472825 cites W2976454318 @default.
• W4311472825 cites W3003543244 @default.
• W4311472825 cites W3036968141 @default.
• W4311472825 cites W3100660218 @default.
• W4311472825 cites W3138702736 @default.
• W4311472825 cites W4200393630 @default.
• W4311472825 cites W4254743277 @default.
• W4311472825 cites W4293276519 @default.
• W4311472825 cites W4293659802 @default.
• W4311472825 cites W821613871 @default.
• W4311472825 cites W3135436225 @default.
• W4311472825 doi "https://doi.org/10.1097/qai.0000000000003143" @default.
• W4311472825 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36515912" @default.
• W4311472825 hasPublicationYear "2023" @default.
• W4311472825 type Work @default.
• W4311472825 citedByCount "1" @default.
• W4311472825 crossrefType "journal-article" @default.
• W4311472825 hasAuthorship W4311472825A5000828542 @default.
• W4311472825 hasAuthorship W4311472825A5010391847 @default.
• W4311472825 hasAuthorship W4311472825A5010665253 @default.
• W4311472825 hasAuthorship W4311472825A5018816959 @default.
• W4311472825 hasAuthorship W4311472825A5025092594 @default.
• W4311472825 hasAuthorship W4311472825A5061940210 @default.
• W4311472825 hasConcept C126322002 @default.
• W4311472825 hasConcept C17991360 @default.
• W4311472825 hasConcept C203014093 @default.
• W4311472825 hasConcept C2776252253 @default.
• W4311472825 hasConcept C2776873419 @default.
• W4311472825 hasConcept C2776914184 @default.
• W4311472825 hasConcept C2776939746 @default.
• W4311472825 hasConcept C2776983459 @default.
• W4311472825 hasConcept C2779384505 @default.
• W4311472825 hasConcept C3013748606 @default.
• W4311472825 hasConcept C71924100 @default.
• W4311472825 hasConcept C72563966 @default.
• W4311472825 hasConcept C8891405 @default.
• W4311472825 hasConcept C90924648 @default.
• W4311472825 hasConceptScore W4311472825C126322002 @default.
• W4311472825 hasConceptScore W4311472825C17991360 @default.
• W4311472825 hasConceptScore W4311472825C203014093 @default.
• W4311472825 hasConceptScore W4311472825C2776252253 @default.
• W4311472825 hasConceptScore W4311472825C2776873419 @default.
• W4311472825 hasConceptScore W4311472825C2776914184 @default.
• W4311472825 hasConceptScore W4311472825C2776939746 @default.
• W4311472825 hasConceptScore W4311472825C2776983459 @default.
• W4311472825 hasConceptScore W4311472825C2779384505 @default.
• W4311472825 hasConceptScore W4311472825C3013748606 @default.
• W4311472825 hasConceptScore W4311472825C71924100 @default.
• W4311472825 hasConceptScore W4311472825C72563966 @default.
• W4311472825 hasConceptScore W4311472825C8891405 @default.
• W4311472825 hasConceptScore W4311472825C90924648 @default.
• W4311472825 hasIssue "4" @default.
• W4311472825 hasLocation W43114728251 @default.
• W4311472825 hasLocation W43114728252 @default.
• W4311472825 hasOpenAccess W4311472825 @default.

• next