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- W4311487385 abstract "Abstract Purpose: As papillary thyroid carcinoma (PTC) is a slow-growing tumor, there are cases where recurrence or metastasis occurs more than 10 years after treatment. Therefore, it is crucial to consider long-term outcomes. In this study, we reported the long-term prognosis of patients with PTC at our institution. Methods: Our retrospective study was conducted on 445 patients with PTC who underwent an initial operation between 1977 and 1996 at our institution and were followed up for at least 1 year. The average age at initial surgery was 52 years, and the mean observation period was 20 years. Results: The disease-specific survival rates (DSS) at 5, 10, 15, 20, and 25 years were 98.6%, 97.1%, 96.2%, 95.5%, and 94.5%, respectively. There were significant differences in OS according to sex, age, pathological node metastasis, and distant metastasis in the multivariate analysis. In patients aged < 55 years, the disease-free survival rates (DFS) at 20 years was 86.5%, while the DSS was 99.1% in stage II. In patients aged ≥ 55 years, DSS and DFS worsened with increasing stage. In N + patients classified as stage II, the prognosis was worse, especially in patients with N1b disease. Conclusion: In patients aged ≥ 55 years, aggressive treatment was necessary for stage III/IV and N1b cases classified as stage II. With the development and widespread use of more advanced equipment, it is expected that treatment decisions will be made based on more accurate preoperative examinations in the future." @default.
- W4311487385 created "2022-12-26" @default.
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- W4311487385 date "2022-12-14" @default.
- W4311487385 modified "2023-10-16" @default.
- W4311487385 title "Long-term treatments results for papillary thyroid carcinoma at a single general hospital" @default.
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- W4311487385 doi "https://doi.org/10.21203/rs.3.rs-2321409/v1" @default.
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