Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311500714> ?p ?o ?g. }
- W4311500714 endingPage "1431" @default.
- W4311500714 startingPage "1420" @default.
- W4311500714 abstract "Target of rapamycin (TOR) functions as a central sensory hub linking a wide range of external stimuli to gene expression. The mechanisms underlying stimulus-specific transcriptional reprogramming by TOR remain elusive. Here, we describe an in silico analysis in Arabidopsis demonstrating that TOR-repressed genes are associated with either bistable or silent chromatin states. Both states regulated by the TOR signaling pathway are associated with a high level of histone H3K27 trimethylation (H3K27me3) deposited by CURLY LEAF in a specific context with LIKE HETEROCHROMATIN PROTEIN1. The combination of the two epigenetic histone modifications H3K4me3 and H3K27me3 implicates a bistable feature that alternates between an 'on' and an 'off' state, allowing rapid transcriptional changes upon external stimuli. The chromatin remodeler SWI2/SNF2 ATPase BRAHMA activates TOR-repressed genes only at bistable chromatin domains to rapidly induce biotic stress responses. Here, we demonstrate both in silico and in vivo that TOR represses transcriptional stress responses through global maintenance of H3K27me3." @default.
- W4311500714 created "2022-12-26" @default.
- W4311500714 creator A5006516949 @default.
- W4311500714 creator A5008166422 @default.
- W4311500714 creator A5010738251 @default.
- W4311500714 creator A5016199737 @default.
- W4311500714 creator A5031207646 @default.
- W4311500714 creator A5052982421 @default.
- W4311500714 creator A5067770356 @default.
- W4311500714 creator A5090648674 @default.
- W4311500714 date "2022-12-14" @default.
- W4311500714 modified "2023-09-28" @default.
- W4311500714 title "TOR represses stress responses through global regulation of H3K27 trimethylation in plants" @default.
- W4311500714 cites W1598154993 @default.
- W4311500714 cites W1693708315 @default.
- W4311500714 cites W1851393262 @default.
- W4311500714 cites W1976387692 @default.
- W4311500714 cites W1992932809 @default.
- W4311500714 cites W2028029749 @default.
- W4311500714 cites W2037480758 @default.
- W4311500714 cites W2101692806 @default.
- W4311500714 cites W2120257398 @default.
- W4311500714 cites W2121444726 @default.
- W4311500714 cites W2131478115 @default.
- W4311500714 cites W2163149892 @default.
- W4311500714 cites W2232608778 @default.
- W4311500714 cites W2258318060 @default.
- W4311500714 cites W2342647777 @default.
- W4311500714 cites W2346309595 @default.
- W4311500714 cites W2420792449 @default.
- W4311500714 cites W2470764536 @default.
- W4311500714 cites W2474139619 @default.
- W4311500714 cites W2713439454 @default.
- W4311500714 cites W2756285137 @default.
- W4311500714 cites W2763009832 @default.
- W4311500714 cites W2767250022 @default.
- W4311500714 cites W2778077257 @default.
- W4311500714 cites W2896869836 @default.
- W4311500714 cites W2913966360 @default.
- W4311500714 cites W2919537409 @default.
- W4311500714 cites W2944090517 @default.
- W4311500714 cites W2950358643 @default.
- W4311500714 cites W2953460064 @default.
- W4311500714 cites W2953462495 @default.
- W4311500714 cites W3035432724 @default.
- W4311500714 cites W3093463309 @default.
- W4311500714 cites W3100684546 @default.
- W4311500714 cites W3104615387 @default.
- W4311500714 cites W3133795834 @default.
- W4311500714 cites W3163559730 @default.
- W4311500714 cites W3206336118 @default.
- W4311500714 cites W4223493017 @default.
- W4311500714 cites W4295763215 @default.
- W4311500714 doi "https://doi.org/10.1093/jxb/erac486" @default.
- W4311500714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36515098" @default.
- W4311500714 hasPublicationYear "2022" @default.
- W4311500714 type Work @default.
- W4311500714 citedByCount "3" @default.
- W4311500714 countsByYear W43115007142023 @default.
- W4311500714 crossrefType "journal-article" @default.
- W4311500714 hasAuthorship W4311500714A5006516949 @default.
- W4311500714 hasAuthorship W4311500714A5008166422 @default.
- W4311500714 hasAuthorship W4311500714A5010738251 @default.
- W4311500714 hasAuthorship W4311500714A5016199737 @default.
- W4311500714 hasAuthorship W4311500714A5031207646 @default.
- W4311500714 hasAuthorship W4311500714A5052982421 @default.
- W4311500714 hasAuthorship W4311500714A5067770356 @default.
- W4311500714 hasAuthorship W4311500714A5090648674 @default.
- W4311500714 hasBestOaLocation W43115007142 @default.
- W4311500714 hasConcept C101762097 @default.
- W4311500714 hasConcept C104317684 @default.
- W4311500714 hasConcept C134320426 @default.
- W4311500714 hasConcept C143065580 @default.
- W4311500714 hasConcept C150194340 @default.
- W4311500714 hasConcept C165864922 @default.
- W4311500714 hasConcept C167227067 @default.
- W4311500714 hasConcept C2779491563 @default.
- W4311500714 hasConcept C2780914512 @default.
- W4311500714 hasConcept C41091548 @default.
- W4311500714 hasConcept C54355233 @default.
- W4311500714 hasConcept C64927066 @default.
- W4311500714 hasConcept C77255625 @default.
- W4311500714 hasConcept C83640560 @default.
- W4311500714 hasConcept C86803240 @default.
- W4311500714 hasConcept C95444343 @default.
- W4311500714 hasConceptScore W4311500714C101762097 @default.
- W4311500714 hasConceptScore W4311500714C104317684 @default.
- W4311500714 hasConceptScore W4311500714C134320426 @default.
- W4311500714 hasConceptScore W4311500714C143065580 @default.
- W4311500714 hasConceptScore W4311500714C150194340 @default.
- W4311500714 hasConceptScore W4311500714C165864922 @default.
- W4311500714 hasConceptScore W4311500714C167227067 @default.
- W4311500714 hasConceptScore W4311500714C2779491563 @default.
- W4311500714 hasConceptScore W4311500714C2780914512 @default.
- W4311500714 hasConceptScore W4311500714C41091548 @default.
- W4311500714 hasConceptScore W4311500714C54355233 @default.
- W4311500714 hasConceptScore W4311500714C64927066 @default.
- W4311500714 hasConceptScore W4311500714C77255625 @default.