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- W4311511261 abstract "Ptychography is an enabling microscopy technique for both fundamental and applied sciences. In the past decade, it has become an indispensable imaging tool in most X-ray synchrotrons and national laboratories worldwide. However, ptychography's limited resolution and throughput in the visible light regime have prevented its wide adoption in biomedical research. Recent developments in this technique have resolved these issues and offer turnkey solutions for high-throughput optical imaging with minimum hardware modifications. The demonstrated imaging throughput is now greater than that of a high-end whole slide scanner. In this review, we discuss the basic principle of ptychography and summarize the main milestones of its development. Different ptychographic implementations are categorized into four groups based on their lensless/lens-based configurations and coded-illumination/coded-detection operations. We also highlight the related biomedical applications, including digital pathology, drug screening, urinalysis, blood analysis, cytometric analysis, rare cell screening, cell culture monitoring, cell and tissue imaging in 2D and 3D, polarimetric analysis, among others. Ptychography for high-throughput optical imaging, currently in its early stages, will continue to improve in performance and expand in its applications. We conclude this review article by pointing out several directions for its future development." @default.
- W4311511261 created "2022-12-26" @default.
- W4311511261 creator A5018085680 @default.
- W4311511261 creator A5032961377 @default.
- W4311511261 creator A5034397838 @default.
- W4311511261 creator A5034869715 @default.
- W4311511261 creator A5041458249 @default.
- W4311511261 creator A5058105700 @default.
- W4311511261 creator A5062535545 @default.
- W4311511261 date "2023-01-03" @default.
- W4311511261 modified "2023-10-14" @default.
- W4311511261 title "Optical ptychography for biomedical imaging: recent progress and future directions [Invited]" @default.
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