FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311542496> ?p ?o ?g. }

• W4311542496 abstract "<sec> <title>BACKGROUND</title> COPD and bronchiectasis are common and exacerbations contribute to their morbidity and mortality. Predictive factors for frequency of future exacerbations include previous exacerbation frequency and airway colonisation. Earlier treatment of exacerbations is likely to reduce severity. </sec> <sec> <title>OBJECTIVE</title> To determine whether changes in physiological variables or symptom scores can predict exacerbations of chronic airway disease in participants colonised with Pseudomonas aeruginosa or Haemophilus influenzae </sec> <sec> <title>METHODS</title> We performed a longitudinal observational cohort study of 30 participants with bronchiectasis and/or COPD, at least 2 exacerbations per year and colonisation with Pseudomonas aeruginosa or Haemophilus influenzae. Daily symptom and physiological data were collected comprising pulse rate, blood pressure, oxygen saturation, peak flow rate, step count, weight and temperature. Exacerbations (defined as the onset of new antibiotics for respiratory symptoms) were collected, and predictive values for abnormal values in the ten days prior to an exacerbation were calculated. </sec> <sec> <title>RESULTS</title> 30 participants were recruited collecting a total of 39,534 physiological and 25,334 symptom data points across 5,358 participant-days including 78 exacerbations. Peak flow rate and weight were significantly different at the point of exacerbation but no significant trends around exacerbation were noted and no clinically beneficial predictive value was found in overall or individually adjusted models. Symptom scores trended to worsening for 10 days either side of an exacerbation, but of insufficient magnitude for prediction with AUROC values of 0.4-0.6. </sec> <sec> <title>CONCLUSIONS</title> This study demonstrated a lack of utility for either physiological or visual analogue scale symptom predictors in early detection of exacerbations in participants with frequent exacerbation and airway colonisation. This suggests that the self-management education provided as standard of care is superior to either of these other approaches. </sec> <sec> <title>INTERNATIONAL REGISTERED REPORT</title> RR2-10.2196/resprot.6636 </sec>" @default.
• W4311542496 created "2022-12-27" @default.
• W4311542496 creator A5005618745 @default.
• W4311542496 creator A5032987491 @default.
• W4311542496 creator A5043863767 @default.
• W4311542496 creator A5046014607 @default.
• W4311542496 creator A5053202299 @default.
• W4311542496 creator A5067586693 @default.
• W4311542496 creator A5086995389 @default.
• W4311542496 date "2022-11-17" @default.
• W4311542496 modified "2023-09-26" @default.
• W4311542496 title "Predictive value of physiological values and symptom scores for exacerbations of COPD and bronchiectasis (Preprint)" @default.
• W4311542496 cites W1979597808 @default.
• W4311542496 cites W2007543639 @default.
• W4311542496 cites W2036751631 @default.
• W4311542496 cites W2039719943 @default.
• W4311542496 cites W2042136708 @default.
• W4311542496 cites W2056573627 @default.
• W4311542496 cites W2056631440 @default.
• W4311542496 cites W2117837864 @default.
• W4311542496 cites W2118858765 @default.
• W4311542496 cites W2150979970 @default.
• W4311542496 cites W2164252380 @default.
• W4311542496 cites W2305013949 @default.
• W4311542496 cites W2312224809 @default.
• W4311542496 cites W2580595281 @default.
• W4311542496 cites W2610558427 @default.
• W4311542496 cites W2791586570 @default.
• W4311542496 cites W2809113250 @default.
• W4311542496 cites W2895902509 @default.
• W4311542496 cites W2904131086 @default.
• W4311542496 cites W2990320915 @default.
• W4311542496 cites W3000258155 @default.
• W4311542496 cites W3011041697 @default.
• W4311542496 cites W3136972068 @default.
• W4311542496 cites W3199451315 @default.
• W4311542496 cites W4210754331 @default.
• W4311542496 cites W4214511362 @default.
• W4311542496 cites W4230836401 @default.
• W4311542496 doi "https://doi.org/10.2196/preprints.44397" @default.
• W4311542496 hasPublicationYear "2022" @default.
• W4311542496 type Work @default.
• W4311542496 citedByCount "0" @default.
• W4311542496 crossrefType "posted-content" @default.
• W4311542496 hasAuthorship W4311542496A5005618745 @default.
• W4311542496 hasAuthorship W4311542496A5032987491 @default.
• W4311542496 hasAuthorship W4311542496A5043863767 @default.
• W4311542496 hasAuthorship W4311542496A5046014607 @default.
• W4311542496 hasAuthorship W4311542496A5053202299 @default.
• W4311542496 hasAuthorship W4311542496A5067586693 @default.
• W4311542496 hasAuthorship W4311542496A5086995389 @default.
• W4311542496 hasConcept C126322002 @default.
• W4311542496 hasConcept C2776780178 @default.
• W4311542496 hasConcept C2776925733 @default.
• W4311542496 hasConcept C2777014857 @default.
• W4311542496 hasConcept C2777714996 @default.
• W4311542496 hasConcept C2779379686 @default.
• W4311542496 hasConcept C501593827 @default.
• W4311542496 hasConcept C71924100 @default.
• W4311542496 hasConcept C86803240 @default.
• W4311542496 hasConcept C89423630 @default.
• W4311542496 hasConceptScore W4311542496C126322002 @default.
• W4311542496 hasConceptScore W4311542496C2776780178 @default.
• W4311542496 hasConceptScore W4311542496C2776925733 @default.
• W4311542496 hasConceptScore W4311542496C2777014857 @default.
• W4311542496 hasConceptScore W4311542496C2777714996 @default.
• W4311542496 hasConceptScore W4311542496C2779379686 @default.
• W4311542496 hasConceptScore W4311542496C501593827 @default.
• W4311542496 hasConceptScore W4311542496C71924100 @default.
• W4311542496 hasConceptScore W4311542496C86803240 @default.
• W4311542496 hasConceptScore W4311542496C89423630 @default.
• W4311542496 hasLocation W43115424961 @default.
• W4311542496 hasOpenAccess W4311542496 @default.
• W4311542496 hasPrimaryLocation W43115424961 @default.
• W4311542496 hasRelatedWork W2163918855 @default.
• W4311542496 hasRelatedWork W2565093911 @default.
• W4311542496 hasRelatedWork W2605886686 @default.
• W4311542496 hasRelatedWork W2776194147 @default.
• W4311542496 hasRelatedWork W2781208394 @default.
• W4311542496 hasRelatedWork W2991308238 @default.
• W4311542496 hasRelatedWork W3001214709 @default.
• W4311542496 hasRelatedWork W3180743555 @default.
• W4311542496 hasRelatedWork W4207014058 @default.
• W4311542496 hasRelatedWork W4213222801 @default.
• W4311542496 isParatext "false" @default.
• W4311542496 isRetracted "false" @default.
• W4311542496 workType "article" @default.