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- W4311576118 abstract "Biologics, a class of medicines grown in and purified from genetically engineered cell cultures, have transformed the management of many cancers and rare diseases, such as paroxysmal nocturnal hemoglobinuria. As prescription drug spending has increased and exclusivity periods have expired, manufacturers have developed biosimilars–biologics that may be more affordable and highly similar to a licensed biological therapeutic, with no clinically meaningful differences in terms of safety or efficacy. With biosimilars gaining regulatory approval around the globe and broadening patient access to biologics, this review aims to help rare disease healthcare providers familiarize themselves with biosimilars, understand their development and regulatory approval process, and address practical considerations that may facilitate their use." @default.
- W4311576118 created "2022-12-27" @default.
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- W4311576118 date "2022-12-15" @default.
- W4311576118 modified "2023-10-18" @default.
- W4311576118 title "Biosimilars in rare diseases - a focus on paroxysmal nocturnal hemoglobinuria" @default.
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- W4311576118 doi "https://doi.org/10.3324/haematol.2022.281562" @default.
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