FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311576345> ?p ?o ?g. }

• W4311576345 endingPage "597" @default.
• W4311576345 startingPage "590" @default.
• W4311576345 abstract "Background: Describing the antihypertensive medication regimens used in the SPRINT (Systolic Blood Pressure Intervention Trial) would contextualize the standard and intensive systolic blood pressure (SBP) interventions and may inform future implementation efforts to achieve population-wide intensive SBP goals. Methods: We included SPRINT participants with complete medication data at the prerandomization and 12-month visits. Regimens were categorized by antihypertensive medication class. Analyses were stratified by treatment group (standard goal SBP <140 mm Hg versus intensive goal SBP <120 mm Hg). Results: Among 7860 participants (83.7% of 9361 randomized), the median number of classes used at the prerandomization visit was 2.0 and 2.0 in the standard and intensive groups ( P =0.559). At 12-months, the median number of classes used was 3.0 and 2.0 in the intensive and standard groups ( P <0.001). Prerandomization, angiotensin-converting enzyme inhibitor (ACE), or angiotensin-II receptor blocker (ARB) monotherapy was the most common regimen in the intensive and standard groups (12.6% versus 12.2%). At 12-months, ACE/ARB monotherapy was still the most common regimen among standard group participants (14.7%) and was used by 5.3% of intensive group participants. Multidrug regimens used by the intensive and standard participants at 12 months were as follows: an ACE/ARB with thiazide (12.2% and 7.9%); an ACE/ARB with calcium channel blocker (6.2% and 6.8%); an ACE/ARB, thiazide, and calcium channel blocker (11.4% and 4.3%); and an ACE/ARB, thiazide, calcium channel blocker, and beta-blocker (6.5% and 1.2%). Conclusions: SPRINT investigators favored combining ACEs or ARBs, thiazide diuretics, and calcium channel blockers to target SBP <120 mm Hg, compared to ACE/ARB monotherapy to target SBP <140 mm Hg. Registration: URL: https://clinicaltrials.gov ; Unique identifier: NCT01206062." @default.
• W4311576345 created "2022-12-27" @default.
• W4311576345 creator A5000565362 @default.
• W4311576345 creator A5006628692 @default.
• W4311576345 creator A5006637299 @default.
• W4311576345 creator A5013709333 @default.
• W4311576345 creator A5016452405 @default.
• W4311576345 creator A5018138746 @default.
• W4311576345 creator A5026789706 @default.
• W4311576345 creator A5031963424 @default.
• W4311576345 creator A5042710227 @default.
• W4311576345 creator A5048334353 @default.
• W4311576345 creator A5052993534 @default.
• W4311576345 creator A5058865250 @default.
• W4311576345 creator A5059108165 @default.
• W4311576345 creator A5073029210 @default.
• W4311576345 creator A5079959622 @default.
• W4311576345 creator A5084279534 @default.
• W4311576345 creator A5087519827 @default.
• W4311576345 creator A5088618031 @default.
• W4311576345 date "2023-03-01" @default.
• W4311576345 modified "2023-10-10" @default.
• W4311576345 title "Antihypertensive Medication Regimens Used in the Systolic Blood Pressure Intervention Trial" @default.
• W4311576345 cites W1554810960 @default.
• W4311576345 cites W1981255881 @default.
• W4311576345 cites W1983526026 @default.
• W4311576345 cites W2000196056 @default.
• W4311576345 cites W2055864845 @default.
• W4311576345 cites W2070289003 @default.
• W4311576345 cites W2086537169 @default.
• W4311576345 cites W2092075924 @default.
• W4311576345 cites W2110880027 @default.
• W4311576345 cites W2111844910 @default.
• W4311576345 cites W2118828750 @default.
• W4311576345 cites W2126125759 @default.
• W4311576345 cites W2129991662 @default.
• W4311576345 cites W2133217116 @default.
• W4311576345 cites W2148092884 @default.
• W4311576345 cites W2156121263 @default.
• W4311576345 cites W2290503308 @default.
• W4311576345 cites W2479171730 @default.
• W4311576345 cites W2513361055 @default.
• W4311576345 cites W2542890482 @default.
• W4311576345 cites W2565707232 @default.
• W4311576345 cites W2614502717 @default.
• W4311576345 cites W2621832667 @default.
• W4311576345 cites W2768267412 @default.
• W4311576345 cites W2792841583 @default.
• W4311576345 cites W2809348670 @default.
• W4311576345 cites W2888589263 @default.
• W4311576345 cites W2928514684 @default.
• W4311576345 cites W3006355415 @default.
• W4311576345 cites W3011410168 @default.
• W4311576345 cites W3119736121 @default.
• W4311576345 cites W3148777843 @default.
• W4311576345 cites W3149811656 @default.
• W4311576345 cites W3150595609 @default.
• W4311576345 cites W3161638097 @default.
• W4311576345 cites W4234562066 @default.
• W4311576345 cites W4238900290 @default.
• W4311576345 cites W4239987022 @default.
• W4311576345 cites W4249101651 @default.
• W4311576345 cites W4283718336 @default.
• W4311576345 doi "https://doi.org/10.1161/hypertensionaha.122.20373" @default.
• W4311576345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36519451" @default.
• W4311576345 hasPublicationYear "2023" @default.
• W4311576345 type Work @default.
• W4311576345 citedByCount "2" @default.
• W4311576345 countsByYear W43115763452023 @default.
• W4311576345 crossrefType "journal-article" @default.
• W4311576345 hasAuthorship W4311576345A5000565362 @default.
• W4311576345 hasAuthorship W4311576345A5006628692 @default.
• W4311576345 hasAuthorship W4311576345A5006637299 @default.
• W4311576345 hasAuthorship W4311576345A5013709333 @default.
• W4311576345 hasAuthorship W4311576345A5016452405 @default.
• W4311576345 hasAuthorship W4311576345A5018138746 @default.
• W4311576345 hasAuthorship W4311576345A5026789706 @default.
• W4311576345 hasAuthorship W4311576345A5031963424 @default.
• W4311576345 hasAuthorship W4311576345A5042710227 @default.
• W4311576345 hasAuthorship W4311576345A5048334353 @default.
• W4311576345 hasAuthorship W4311576345A5052993534 @default.
• W4311576345 hasAuthorship W4311576345A5058865250 @default.
• W4311576345 hasAuthorship W4311576345A5059108165 @default.
• W4311576345 hasAuthorship W4311576345A5073029210 @default.
• W4311576345 hasAuthorship W4311576345A5079959622 @default.
• W4311576345 hasAuthorship W4311576345A5084279534 @default.
• W4311576345 hasAuthorship W4311576345A5087519827 @default.
• W4311576345 hasAuthorship W4311576345A5088618031 @default.
• W4311576345 hasConcept C104849204 @default.
• W4311576345 hasConcept C126322002 @default.
• W4311576345 hasConcept C2780356492 @default.
• W4311576345 hasConcept C2780437262 @default.
• W4311576345 hasConcept C2781413609 @default.
• W4311576345 hasConcept C2908647359 @default.
• W4311576345 hasConcept C2908929049 @default.
• W4311576345 hasConcept C71924100 @default.
• W4311576345 hasConcept C84393581 @default.
• W4311576345 hasConcept C99454951 @default.

• next