Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311585973> ?p ?o ?g. }
- W4311585973 endingPage "574" @default.
- W4311585973 startingPage "561" @default.
- W4311585973 abstract "Background Testicular function, including compensated Leydig cell function, has been indicated to be an early marker of morbidity. Objective To study the association of testicular function and markers of metabolic and cardiovascular health in a population of young men. Materials and methods A cross-sectional study of 2289 men (median age 19 years, 5–95 percentile 18.4–22.2) from the general population examined between 2012 and 2019. Participants answered a questionnaire, had a blood sample drawn for assessment of reproductive hormone levels and health markers (lipids, glycosylated hemoglobin), delivered a semen sample, underwent physical examination including blood pressure measurements, and dual-energy X-ray absorptiometry scan for assessment of body composition. Associations were assessed in both crude and adjusted linear regression analyses. Results The men were within the normal reference intervals of their age for reproductive and health biomarkers. Compared to the lowest quartile, having luteinizing hormone levels in the highest quartile was associated with higher mean arterial pressure (1.6 [95% confidence interval: 0.8; 2.5] mmHg), cholesterol (0.1 [95% confidence interval: 0.02; 0.18] mmol/L), and total body fat percentage (1.1 [95% confidence interval: 0.4; 1.8] %-points). Higher serum testosterone levels were associated with more advantageous cardiometabolic health markers and higher total sperm count with a healthier body composition and lower glycosylated hemoglobin. Discussion and conclusion In this study of young men, unselected regarding reproductive hormones and semen quality, higher luteinizing hormone was associated with cardiovascular risk factors. Higher testosterone and total sperm count were associated with more favorable cardiometabolic indices. Thus, serum reproductive hormones and semen quality may be early appearing biomarkers of cardiovascular health even among young healthy men, which could potentially be useful for preventive initiatives to reduce the excess mortality and morbidity risk among infertile men. However, our study was cross-sectional and cannot determine causation. Future longitudinal studies of reproductive health in young men are warranted." @default.
- W4311585973 created "2022-12-27" @default.
- W4311585973 creator A5030655520 @default.
- W4311585973 creator A5038402772 @default.
- W4311585973 creator A5043899152 @default.
- W4311585973 creator A5057771370 @default.
- W4311585973 creator A5059710601 @default.
- W4311585973 creator A5066087996 @default.
- W4311585973 creator A5080896292 @default.
- W4311585973 date "2023-01-12" @default.
- W4311585973 modified "2023-10-16" @default.
- W4311585973 title "Testicular function is associated with cardiometabolic health markers: A cross‐sectional study of 2289 young men" @default.
- W4311585973 cites W1532549004 @default.
- W4311585973 cites W1839674266 @default.
- W4311585973 cites W1987977957 @default.
- W4311585973 cites W1988292778 @default.
- W4311585973 cites W2063265603 @default.
- W4311585973 cites W2077140741 @default.
- W4311585973 cites W2098247759 @default.
- W4311585973 cites W2110425298 @default.
- W4311585973 cites W2113393026 @default.
- W4311585973 cites W2128021607 @default.
- W4311585973 cites W2134765601 @default.
- W4311585973 cites W2136449685 @default.
- W4311585973 cites W2147452407 @default.
- W4311585973 cites W2151733245 @default.
- W4311585973 cites W2155228880 @default.
- W4311585973 cites W2159902645 @default.
- W4311585973 cites W2165913105 @default.
- W4311585973 cites W2171960881 @default.
- W4311585973 cites W2266080210 @default.
- W4311585973 cites W2290784573 @default.
- W4311585973 cites W2329192296 @default.
- W4311585973 cites W2330178519 @default.
- W4311585973 cites W2467329536 @default.
- W4311585973 cites W2571450722 @default.
- W4311585973 cites W2612160773 @default.
- W4311585973 cites W2612901232 @default.
- W4311585973 cites W2726109387 @default.
- W4311585973 cites W2765971218 @default.
- W4311585973 cites W2791383766 @default.
- W4311585973 cites W2804840597 @default.
- W4311585973 cites W2887064834 @default.
- W4311585973 cites W2888025232 @default.
- W4311585973 cites W2896656730 @default.
- W4311585973 cites W2969047831 @default.
- W4311585973 cites W3023768774 @default.
- W4311585973 cites W3093213013 @default.
- W4311585973 cites W3119203409 @default.
- W4311585973 cites W3160982698 @default.
- W4311585973 cites W3210810502 @default.
- W4311585973 doi "https://doi.org/10.1111/andr.13365" @default.
- W4311585973 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36520458" @default.
- W4311585973 hasPublicationYear "2023" @default.
- W4311585973 type Work @default.
- W4311585973 citedByCount "0" @default.
- W4311585973 crossrefType "journal-article" @default.
- W4311585973 hasAuthorship W4311585973A5030655520 @default.
- W4311585973 hasAuthorship W4311585973A5038402772 @default.
- W4311585973 hasAuthorship W4311585973A5043899152 @default.
- W4311585973 hasAuthorship W4311585973A5057771370 @default.
- W4311585973 hasAuthorship W4311585973A5059710601 @default.
- W4311585973 hasAuthorship W4311585973A5066087996 @default.
- W4311585973 hasAuthorship W4311585973A5080896292 @default.
- W4311585973 hasConcept C126322002 @default.
- W4311585973 hasConcept C134018914 @default.
- W4311585973 hasConcept C142052008 @default.
- W4311585973 hasConcept C142724271 @default.
- W4311585973 hasConcept C16685009 @default.
- W4311585973 hasConcept C2778080409 @default.
- W4311585973 hasConcept C2778093475 @default.
- W4311585973 hasConcept C2778575703 @default.
- W4311585973 hasConcept C2779279991 @default.
- W4311585973 hasConcept C2779874844 @default.
- W4311585973 hasConcept C2908647359 @default.
- W4311585973 hasConcept C29456083 @default.
- W4311585973 hasConcept C42407357 @default.
- W4311585973 hasConcept C44249647 @default.
- W4311585973 hasConcept C68443243 @default.
- W4311585973 hasConcept C71315377 @default.
- W4311585973 hasConcept C71924100 @default.
- W4311585973 hasConcept C84393581 @default.
- W4311585973 hasConcept C99454951 @default.
- W4311585973 hasConceptScore W4311585973C126322002 @default.
- W4311585973 hasConceptScore W4311585973C134018914 @default.
- W4311585973 hasConceptScore W4311585973C142052008 @default.
- W4311585973 hasConceptScore W4311585973C142724271 @default.
- W4311585973 hasConceptScore W4311585973C16685009 @default.
- W4311585973 hasConceptScore W4311585973C2778080409 @default.
- W4311585973 hasConceptScore W4311585973C2778093475 @default.
- W4311585973 hasConceptScore W4311585973C2778575703 @default.
- W4311585973 hasConceptScore W4311585973C2779279991 @default.
- W4311585973 hasConceptScore W4311585973C2779874844 @default.
- W4311585973 hasConceptScore W4311585973C2908647359 @default.
- W4311585973 hasConceptScore W4311585973C29456083 @default.
- W4311585973 hasConceptScore W4311585973C42407357 @default.
- W4311585973 hasConceptScore W4311585973C44249647 @default.
- W4311585973 hasConceptScore W4311585973C68443243 @default.