FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311586377> ?p ?o ?g. }

• W4311586377 endingPage "13" @default.
• W4311586377 startingPage "1" @default.
• W4311586377 abstract "While restricting nutrition can improve diseases related to the digestive tract, excessive restriction of food intake can also lead to malnutrition and delayed physical growth. Therefore, this brings the demand to study the effect and potential mechanism of restricted feeding on skeletal muscle development in rabbits. This study utilized hematoxylin-eosin (HE) staining to detect muscle fiber area which depicted significant reduction in skeletal muscle fiber upon 30% feed restriction (p < 0.05). The control group and 30% feed restricted group showed 615 deferentially expressed genes (DEGs). Through the GO and KEGG functional enrichment analysis demonstrated 28 DEGs related to muscle development. KEGG analysis showed enrichment of pathways including PI3K/Akt signaling pathway, MAPK signaling pathway, and Hedgehog signaling pathway. Further, the full length of troponin I1, slow skeletal type (TNNI1) was cloned. We studied the expression of skeletal muscle differentiation-related genes such as MyoD, Myf5 gene and Desmin. Specifically, the TNNI1 gene overexpression and knockdown studies were conducted. The over-expression of TNNI1 significantly enhanced the expression of the skeletal muscle development-related genes. Contrastingly, the silencing of TNNI1 gene reduced the expression significantly. These findings showed that TNNI1 may be a regulator for regulating the expression of muscle development-related genes." @default.
• W4311586377 created "2022-12-27" @default.
• W4311586377 creator A5009866828 @default.
• W4311586377 creator A5012283619 @default.
• W4311586377 creator A5016225178 @default.
• W4311586377 creator A5020819058 @default.
• W4311586377 creator A5026686675 @default.
• W4311586377 creator A5031098594 @default.
• W4311586377 creator A5052861047 @default.
• W4311586377 creator A5055436613 @default.
• W4311586377 creator A5082947695 @default.
• W4311586377 creator A5083726106 @default.
• W4311586377 date "2022-12-15" @default.
• W4311586377 modified "2023-09-27" @default.
• W4311586377 title "Effects of feeding restriction on skeletal muscle development and functional analysis of <i>TNNI1</i> in New Zealand white rabbits" @default.
• W4311586377 cites W1481026039 @default.
• W4311586377 cites W1530473805 @default.
• W4311586377 cites W1964531952 @default.
• W4311586377 cites W1966410154 @default.
• W4311586377 cites W1969866001 @default.
• W4311586377 cites W1974956293 @default.
• W4311586377 cites W2004914475 @default.
• W4311586377 cites W2014873002 @default.
• W4311586377 cites W2017048449 @default.
• W4311586377 cites W2024486921 @default.
• W4311586377 cites W2030917054 @default.
• W4311586377 cites W2044398364 @default.
• W4311586377 cites W2065224760 @default.
• W4311586377 cites W2066215092 @default.
• W4311586377 cites W2067546983 @default.
• W4311586377 cites W2084839996 @default.
• W4311586377 cites W2097363242 @default.
• W4311586377 cites W2119932644 @default.
• W4311586377 cites W2136626081 @default.
• W4311586377 cites W2145931730 @default.
• W4311586377 cites W2146335442 @default.
• W4311586377 cites W2148772907 @default.
• W4311586377 cites W2155028668 @default.
• W4311586377 cites W2156696514 @default.
• W4311586377 cites W2158321488 @default.
• W4311586377 cites W2165711046 @default.
• W4311586377 cites W2266398926 @default.
• W4311586377 cites W2409354348 @default.
• W4311586377 cites W2417451279 @default.
• W4311586377 cites W2756542683 @default.
• W4311586377 cites W2765237779 @default.
• W4311586377 cites W2988977772 @default.
• W4311586377 doi "https://doi.org/10.1080/10495398.2022.2155662" @default.
• W4311586377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36520026" @default.
• W4311586377 hasPublicationYear "2022" @default.
• W4311586377 type Work @default.
• W4311586377 citedByCount "0" @default.
• W4311586377 crossrefType "journal-article" @default.
• W4311586377 hasAuthorship W4311586377A5009866828 @default.
• W4311586377 hasAuthorship W4311586377A5012283619 @default.
• W4311586377 hasAuthorship W4311586377A5016225178 @default.
• W4311586377 hasAuthorship W4311586377A5020819058 @default.
• W4311586377 hasAuthorship W4311586377A5026686675 @default.
• W4311586377 hasAuthorship W4311586377A5031098594 @default.
• W4311586377 hasAuthorship W4311586377A5052861047 @default.
• W4311586377 hasAuthorship W4311586377A5055436613 @default.
• W4311586377 hasAuthorship W4311586377A5082947695 @default.
• W4311586377 hasAuthorship W4311586377A5083726106 @default.
• W4311586377 hasConcept C126322002 @default.
• W4311586377 hasConcept C134018914 @default.
• W4311586377 hasConcept C147447768 @default.
• W4311586377 hasConcept C203014093 @default.
• W4311586377 hasConcept C204232928 @default.
• W4311586377 hasConcept C2777488582 @default.
• W4311586377 hasConcept C2778106681 @default.
• W4311586377 hasConcept C2778463287 @default.
• W4311586377 hasConcept C2779072444 @default.
• W4311586377 hasConcept C2779959927 @default.
• W4311586377 hasConcept C2780508455 @default.
• W4311586377 hasConcept C3763915 @default.
• W4311586377 hasConcept C62478195 @default.
• W4311586377 hasConcept C71924100 @default.
• W4311586377 hasConcept C86803240 @default.
• W4311586377 hasConcept C88498014 @default.
• W4311586377 hasConcept C95444343 @default.
• W4311586377 hasConcept C97816823 @default.
• W4311586377 hasConceptScore W4311586377C126322002 @default.
• W4311586377 hasConceptScore W4311586377C134018914 @default.
• W4311586377 hasConceptScore W4311586377C147447768 @default.
• W4311586377 hasConceptScore W4311586377C203014093 @default.
• W4311586377 hasConceptScore W4311586377C204232928 @default.
• W4311586377 hasConceptScore W4311586377C2777488582 @default.
• W4311586377 hasConceptScore W4311586377C2778106681 @default.
• W4311586377 hasConceptScore W4311586377C2778463287 @default.
• W4311586377 hasConceptScore W4311586377C2779072444 @default.
• W4311586377 hasConceptScore W4311586377C2779959927 @default.
• W4311586377 hasConceptScore W4311586377C2780508455 @default.
• W4311586377 hasConceptScore W4311586377C3763915 @default.
• W4311586377 hasConceptScore W4311586377C62478195 @default.
• W4311586377 hasConceptScore W4311586377C71924100 @default.
• W4311586377 hasConceptScore W4311586377C86803240 @default.
• W4311586377 hasConceptScore W4311586377C88498014 @default.
• W4311586377 hasConceptScore W4311586377C95444343 @default.

• next