FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311587057> ?p ?o ?g. }

• W4311587057 abstract "Abstract Aquatic microbial communities are an important reservoir of antibiotic resistance genes (ARGs). However, distribution and diversity of different ARG categories in environmental microbes with different ecological strategies is not yet well studied. Despite the potential exposure of the southern part of the Caspian Sea to the release of antibiotics, little is known about its natural resistome profile. We used a combination of Hidden Markov model (HMM), homology alignment and a deep learning approach for comprehensive screening of the diversity and distribution of ARGs in the Caspian Sea metagenomes at genome resolution. Detected ARGs were classified into five antibiotic resistance categories including prevention of access to target (44%), modification/protection of targets (30%), direct modification of antibiotics (22%), stress resistance (3%), and metal resistance (1%). The 102 detected ARG containing metagenome-assembled genomes of the Caspian Sea were dominated by representatives of Acidimicrobiia, Gammaproteobacteria, and Actinobacteria classes. Comparative analysis revealed that the highly abundant, oligotrophic, and genome streamlined representatives of taxa Acidimicrobiia and Actinobacteria modify the antibiotic target via mutation to develop antibiotic resistance rather than carrying extra resistance genes. Our results help with understanding how the encoded resistance categories of each genome are aligned with its ecological strategies." @default.
• W4311587057 created "2022-12-27" @default.
• W4311587057 creator A5022032184 @default.
• W4311587057 creator A5029716031 @default.
• W4311587057 creator A5044503981 @default.
• W4311587057 date "2022-12-06" @default.
• W4311587057 modified "2023-10-14" @default.
• W4311587057 title "Genome-resolved insight into the reservoir of antibiotic resistance genes in aquatic microbial community" @default.
• W4311587057 cites W1924338650 @default.
• W4311587057 cites W1985716049 @default.
• W4311587057 cites W1995448590 @default.
• W4311587057 cites W1999396043 @default.
• W4311587057 cites W2004960255 @default.
• W4311587057 cites W2017911769 @default.
• W4311587057 cites W2027184506 @default.
• W4311587057 cites W2032808656 @default.
• W4311587057 cites W2056857562 @default.
• W4311587057 cites W2076505260 @default.
• W4311587057 cites W2084203472 @default.
• W4311587057 cites W2092643722 @default.
• W4311587057 cites W2096369133 @default.
• W4311587057 cites W2106882534 @default.
• W4311587057 cites W2112364185 @default.
• W4311587057 cites W2116402302 @default.
• W4311587057 cites W2117689688 @default.
• W4311587057 cites W2118688136 @default.
• W4311587057 cites W2139459279 @default.
• W4311587057 cites W2142343447 @default.
• W4311587057 cites W2143485490 @default.
• W4311587057 cites W2150547022 @default.
• W4311587057 cites W2150860868 @default.
• W4311587057 cites W2150906077 @default.
• W4311587057 cites W2152127318 @default.
• W4311587057 cites W2165853813 @default.
• W4311587057 cites W2178043251 @default.
• W4311587057 cites W2224741923 @default.
• W4311587057 cites W2513408189 @default.
• W4311587057 cites W2569572906 @default.
• W4311587057 cites W2594303706 @default.
• W4311587057 cites W2599417231 @default.
• W4311587057 cites W2763159727 @default.
• W4311587057 cites W2794891594 @default.
• W4311587057 cites W2799524357 @default.
• W4311587057 cites W2799649967 @default.
• W4311587057 cites W2803363861 @default.
• W4311587057 cites W2803599078 @default.
• W4311587057 cites W2900629010 @default.
• W4311587057 cites W2915050491 @default.
• W4311587057 cites W2918063357 @default.
• W4311587057 cites W2927600655 @default.
• W4311587057 cites W2936672112 @default.
• W4311587057 cites W2938868597 @default.
• W4311587057 cites W2951274106 @default.
• W4311587057 cites W2953307385 @default.
• W4311587057 cites W2967125766 @default.
• W4311587057 cites W2969465689 @default.
• W4311587057 cites W2982531601 @default.
• W4311587057 cites W2986925300 @default.
• W4311587057 cites W2991012415 @default.
• W4311587057 cites W3004493607 @default.
• W4311587057 cites W3006574710 @default.
• W4311587057 cites W3007115203 @default.
• W4311587057 cites W3015408204 @default.
• W4311587057 cites W3023081306 @default.
• W4311587057 cites W3032191947 @default.
• W4311587057 cites W3042826286 @default.
• W4311587057 cites W3048398081 @default.
• W4311587057 cites W3081751155 @default.
• W4311587057 cites W3095583226 @default.
• W4311587057 cites W3106923768 @default.
• W4311587057 cites W3115291568 @default.
• W4311587057 cites W3122622254 @default.
• W4311587057 cites W3127656915 @default.
• W4311587057 cites W3131205430 @default.
• W4311587057 cites W3135303689 @default.
• W4311587057 cites W3156458251 @default.
• W4311587057 cites W3193473972 @default.
• W4311587057 cites W3210890336 @default.
• W4311587057 cites W3212576328 @default.
• W4311587057 cites W4226116133 @default.
• W4311587057 doi "https://doi.org/10.1038/s41598-022-25026-3" @default.
• W4311587057 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36473884" @default.
• W4311587057 hasPublicationYear "2022" @default.
• W4311587057 type Work @default.
• W4311587057 citedByCount "0" @default.
• W4311587057 crossrefType "journal-article" @default.
• W4311587057 hasAuthorship W4311587057A5022032184 @default.
• W4311587057 hasAuthorship W4311587057A5029716031 @default.
• W4311587057 hasAuthorship W4311587057A5044503981 @default.
• W4311587057 hasBestOaLocation W43115870571 @default.
• W4311587057 hasConcept C104317684 @default.
• W4311587057 hasConcept C141231307 @default.
• W4311587057 hasConcept C15151743 @default.
• W4311587057 hasConcept C18903297 @default.
• W4311587057 hasConcept C2776650774 @default.
• W4311587057 hasConcept C2776666601 @default.
• W4311587057 hasConcept C2776989901 @default.
• W4311587057 hasConcept C2778169975 @default.
• W4311587057 hasConcept C42062724 @default.
• W4311587057 hasConcept C501593827 @default.

• next