FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311605631> ?p ?o ?g. }

• W4311605631 abstract "Infectious meningitis and encephalitis (ME) are life-threatening conditions are caused by various pathogens. Conventional laboratory tests with low sensitivity and specificity cannot help with early diagnosis.A prospective study using the novel multiplex PCR detection for 18 pathogens of ME (MME-18) was conducted to investigate the clinical utilization and the epidemiology characteristics of ME in southwestern China. Patients with suspected intracranial infection were recruited between May and October 2019 at West China Hospital of Sichuan University. The MME-18 was used to detect cerebrospinal fluid, and conventional experiments including cryptococcal capsular antigen detection, GeneXpert, real-time PCR, and clinical feedback were used to verify the result of MME-18.Among 581 tested patients, 139 eligible individuals were enrolled in the study. Among them, Mycobacterium tuberculosis was the most common pathogen in mono-infection. Viruses and Cryptococcus neoformans were also frequently detected. Of 139 infected patients, 12 cases were diagnosed by MME-18 only, 57 patients by conventional testing only, and 70 cases by both comparator tests and MME-18. There were 96.3% (79/82) diagnoses made by MME-18 had a favorable outcome, and two of twelve diagnoses, made solely by MME-18, had a likely unclear clinical significance.The MME-18 showed satisfactory consistency with expert clinical consensus for patients presenting with ME. Combined with conventional testing and clinical suspicion, MME-18 may help clinicians with the early identification of pathogens." @default.
• W4311605631 created "2022-12-27" @default.
• W4311605631 creator A5007982133 @default.
• W4311605631 creator A5022802222 @default.
• W4311605631 creator A5039298853 @default.
• W4311605631 creator A5057490932 @default.
• W4311605631 creator A5068703836 @default.
• W4311605631 creator A5082878086 @default.
• W4311605631 creator A5088115066 @default.
• W4311605631 date "2022-12-16" @default.
• W4311605631 modified "2023-09-27" @default.
• W4311605631 title "Multiplex detection of meningitis and encephalitis pathogens: A study from laboratory to clinic" @default.
• W4311605631 cites W1814550531 @default.
• W4311605631 cites W1983413196 @default.
• W4311605631 cites W1987052708 @default.
• W4311605631 cites W2009379826 @default.
• W4311605631 cites W2015884528 @default.
• W4311605631 cites W2064174776 @default.
• W4311605631 cites W2079513681 @default.
• W4311605631 cites W2096019871 @default.
• W4311605631 cites W2108054631 @default.
• W4311605631 cites W2127774996 @default.
• W4311605631 cites W2129689919 @default.
• W4311605631 cites W2136484280 @default.
• W4311605631 cites W2146484568 @default.
• W4311605631 cites W2160348833 @default.
• W4311605631 cites W2167745547 @default.
• W4311605631 cites W2234114364 @default.
• W4311605631 cites W2326122211 @default.
• W4311605631 cites W2341791533 @default.
• W4311605631 cites W2346004123 @default.
• W4311605631 cites W2410125535 @default.
• W4311605631 cites W2460625652 @default.
• W4311605631 cites W2606340109 @default.
• W4311605631 cites W2606361893 @default.
• W4311605631 cites W2620144886 @default.
• W4311605631 cites W2749336049 @default.
• W4311605631 cites W2786291767 @default.
• W4311605631 cites W2789856846 @default.
• W4311605631 cites W2801569283 @default.
• W4311605631 cites W2889457421 @default.
• W4311605631 cites W2903626816 @default.
• W4311605631 cites W2912679745 @default.
• W4311605631 cites W2943488685 @default.
• W4311605631 cites W2953017819 @default.
• W4311605631 cites W3012001776 @default.
• W4311605631 cites W3041512338 @default.
• W4311605631 cites W3096406237 @default.
• W4311605631 cites W4205341893 @default.
• W4311605631 cites W4206815970 @default.
• W4311605631 cites W4221092398 @default.
• W4311605631 doi "https://doi.org/10.3389/fneur.2022.1054071" @default.
• W4311605631 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36588904" @default.
• W4311605631 hasPublicationYear "2022" @default.
• W4311605631 type Work @default.
• W4311605631 citedByCount "0" @default.
• W4311605631 crossrefType "journal-article" @default.
• W4311605631 hasAuthorship W4311605631A5007982133 @default.
• W4311605631 hasAuthorship W4311605631A5022802222 @default.
• W4311605631 hasAuthorship W4311605631A5039298853 @default.
• W4311605631 hasAuthorship W4311605631A5057490932 @default.
• W4311605631 hasAuthorship W4311605631A5068703836 @default.
• W4311605631 hasAuthorship W4311605631A5082878086 @default.
• W4311605631 hasAuthorship W4311605631A5088115066 @default.
• W4311605631 hasBestOaLocation W43116056311 @default.
• W4311605631 hasConcept C107130276 @default.
• W4311605631 hasConcept C126265401 @default.
• W4311605631 hasConcept C126322002 @default.
• W4311605631 hasConcept C142724271 @default.
• W4311605631 hasConcept C187212893 @default.
• W4311605631 hasConcept C203014093 @default.
• W4311605631 hasConcept C2522874641 @default.
• W4311605631 hasConcept C2777893358 @default.
• W4311605631 hasConcept C2777975735 @default.
• W4311605631 hasConcept C2781026528 @default.
• W4311605631 hasConcept C2781069245 @default.
• W4311605631 hasConcept C534262118 @default.
• W4311605631 hasConcept C71924100 @default.
• W4311605631 hasConcept C83455156 @default.
• W4311605631 hasConcept C86803240 @default.
• W4311605631 hasConcept C89423630 @default.
• W4311605631 hasConceptScore W4311605631C107130276 @default.
• W4311605631 hasConceptScore W4311605631C126265401 @default.
• W4311605631 hasConceptScore W4311605631C126322002 @default.
• W4311605631 hasConceptScore W4311605631C142724271 @default.
• W4311605631 hasConceptScore W4311605631C187212893 @default.
• W4311605631 hasConceptScore W4311605631C203014093 @default.
• W4311605631 hasConceptScore W4311605631C2522874641 @default.
• W4311605631 hasConceptScore W4311605631C2777893358 @default.
• W4311605631 hasConceptScore W4311605631C2777975735 @default.
• W4311605631 hasConceptScore W4311605631C2781026528 @default.
• W4311605631 hasConceptScore W4311605631C2781069245 @default.
• W4311605631 hasConceptScore W4311605631C534262118 @default.
• W4311605631 hasConceptScore W4311605631C71924100 @default.
• W4311605631 hasConceptScore W4311605631C83455156 @default.
• W4311605631 hasConceptScore W4311605631C86803240 @default.
• W4311605631 hasConceptScore W4311605631C89423630 @default.
• W4311605631 hasFunder F4320323137 @default.
• W4311605631 hasFunder F4320336042 @default.
• W4311605631 hasLocation W43116056311 @default.

• next