FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311619380> ?p ?o ?g. }

• W4311619380 abstract "Intensive care unit (ICU) prolonged immobilization may lead to lower-extremity muscle deconditioning among critically ill patients, particularly more accentuated in those with 2019 Novel Coronavirus (COVID-19) infection. Electrical stimulation (E-Stim) is known to improve musculoskeletal outcomes. This phase I double-blinded randomized controlled trial examined the safety and efficacy of lower-extremity E-Stim to prevent muscle deconditioning.Critically ill COVID-19 patients admitted to the ICU were randomly assigned to control (CG) or intervention (IG) groups. Both groups received daily E-Stim (1 h) for up to 14 days on both gastrocnemius muscles (GNMs). The device was functional in the IG and non-functional in the CG. Primary outcomes included ankle strength (Ankles) measured by an ankle-dynamometer, and GNM endurance (GNMe) in response to E-Stim assessed with surface electromyography (sEMG). Outcomes were measured at baseline, 3 and 9 days.Thirty-two (IG = 16, CG = 16) lower extremities in 16 patients were independently assessed. The mean time between ICU admission and E-Stim therapy delivery was 1.8 ± 1.9 days (p = 0.29). At 3 days, the IG showed an improvement compared to the CG with medium effect sizes for Ankles (p = 0.06, Cohen's d = 0.77) and GNMe (p = 0.06, d = 0.69). At 9 days, the IG GNMe was significantly higher than the CG (p = 0.04, d = 0.97) with a 6.3% improvement from baseline (p = 0.029). E-Stim did not alter vital signs (i.e., heart/respiratory rate, blood saturation of oxygen), showed no adverse events (i.e., pain, skin damage, discomfort), nor interfere with ICU standard of care procedures (i.e., mechanical ventilation, prone rotation).This study supports the safety and efficacy of early E-Stim therapy to potentially prevent deterioration of lower-extremity muscle conditions in critically ill COVID-19 patients recently admitted to the ICU. If confirmed in a larger sample, E-Stim may be used as a practical adjunctive therapy.[https://clinicaltrials.gov/], identifier [NCT04685213]." @default.
• W4311619380 created "2022-12-27" @default.
• W4311619380 creator A5019147774 @default.
• W4311619380 creator A5032214429 @default.
• W4311619380 creator A5043769250 @default.
• W4311619380 creator A5048228089 @default.
• W4311619380 creator A5051401339 @default.
• W4311619380 creator A5067280717 @default.
• W4311619380 creator A5077594687 @default.
• W4311619380 creator A5088743054 @default.
• W4311619380 creator A5089717714 @default.
• W4311619380 date "2022-12-06" @default.
• W4311619380 modified "2023-10-14" @default.
• W4311619380 title "Safety and efficacy of electrical stimulation for lower-extremity muscle weakness in intensive care unit 2019 Novel Coronavirus patients: A phase I double-blinded randomized controlled trial" @default.
• W4311619380 cites W1498420397 @default.
• W4311619380 cites W1565234562 @default.
• W4311619380 cites W1962968802 @default.
• W4311619380 cites W1964493140 @default.
• W4311619380 cites W1965067883 @default.
• W4311619380 cites W1986210993 @default.
• W4311619380 cites W2000439420 @default.
• W4311619380 cites W2005898428 @default.
• W4311619380 cites W2045885579 @default.
• W4311619380 cites W2064661906 @default.
• W4311619380 cites W2066047248 @default.
• W4311619380 cites W2071311008 @default.
• W4311619380 cites W2088925411 @default.
• W4311619380 cites W2102557508 @default.
• W4311619380 cites W2106246207 @default.
• W4311619380 cites W2107528330 @default.
• W4311619380 cites W2111861407 @default.
• W4311619380 cites W2118240638 @default.
• W4311619380 cites W2128378039 @default.
• W4311619380 cites W2145878627 @default.
• W4311619380 cites W2148882132 @default.
• W4311619380 cites W2149305913 @default.
• W4311619380 cites W2150947082 @default.
• W4311619380 cites W2163284095 @default.
• W4311619380 cites W2170259406 @default.
• W4311619380 cites W2178401497 @default.
• W4311619380 cites W2337599582 @default.
• W4311619380 cites W2417386455 @default.
• W4311619380 cites W2418826949 @default.
• W4311619380 cites W2465718901 @default.
• W4311619380 cites W2508472223 @default.
• W4311619380 cites W2510337174 @default.
• W4311619380 cites W2517976098 @default.
• W4311619380 cites W2521752244 @default.
• W4311619380 cites W2555448912 @default.
• W4311619380 cites W2556328769 @default.
• W4311619380 cites W2591130756 @default.
• W4311619380 cites W2600716716 @default.
• W4311619380 cites W2764143438 @default.
• W4311619380 cites W2771027414 @default.
• W4311619380 cites W2771323817 @default.
• W4311619380 cites W2810925040 @default.
• W4311619380 cites W2897430333 @default.
• W4311619380 cites W2917775287 @default.
• W4311619380 cites W2947468716 @default.
• W4311619380 cites W2960752454 @default.
• W4311619380 cites W2969370339 @default.
• W4311619380 cites W2993720824 @default.
• W4311619380 cites W3011614543 @default.
• W4311619380 cites W3027634504 @default.
• W4311619380 cites W3038001133 @default.
• W4311619380 cites W3040987569 @default.
• W4311619380 cites W3108675293 @default.
• W4311619380 cites W3122382119 @default.
• W4311619380 cites W3128552227 @default.
• W4311619380 cites W3130768220 @default.
• W4311619380 cites W3134465108 @default.
• W4311619380 cites W3135716894 @default.
• W4311619380 cites W3155766687 @default.
• W4311619380 cites W3159600518 @default.
• W4311619380 cites W3183286355 @default.
• W4311619380 cites W3184846981 @default.
• W4311619380 cites W3184939524 @default.
• W4311619380 cites W4206967190 @default.
• W4311619380 cites W4212834656 @default.
• W4311619380 cites W4229376234 @default.
• W4311619380 cites W4232015630 @default.
• W4311619380 cites W4235556048 @default.
• W4311619380 doi "https://doi.org/10.3389/fmed.2022.1017371" @default.
• W4311619380 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36561714" @default.
• W4311619380 hasPublicationYear "2022" @default.
• W4311619380 type Work @default.
• W4311619380 citedByCount "2" @default.
• W4311619380 countsByYear W43116193802023 @default.
• W4311619380 crossrefType "journal-article" @default.
• W4311619380 hasAuthorship W4311619380A5019147774 @default.
• W4311619380 hasAuthorship W4311619380A5032214429 @default.
• W4311619380 hasAuthorship W4311619380A5043769250 @default.
• W4311619380 hasAuthorship W4311619380A5048228089 @default.
• W4311619380 hasAuthorship W4311619380A5051401339 @default.
• W4311619380 hasAuthorship W4311619380A5067280717 @default.
• W4311619380 hasAuthorship W4311619380A5077594687 @default.
• W4311619380 hasAuthorship W4311619380A5088743054 @default.
• W4311619380 hasAuthorship W4311619380A5089717714 @default.
• W4311619380 hasBestOaLocation W43116193801 @default.
• W4311619380 hasConcept C126322002 @default.

• next