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• W4311621319 endingPage "252" @default.
• W4311621319 startingPage "246" @default.
• W4311621319 abstract "Introduction Negative outcomes, including suicidal ideation/attempts, are a major public health concern, particularly among individuals who sustain a traumatic brain injury (TBI). TBI is associated with high rates of postinjury substance use, psychiatric disorders, post-traumatic stress disorder and sleep disturbances. This study examines the mediation effects of substance use, psychiatric disorder and sleep disorder on the associations between TBI and suicidal ideation/attempts. Methods A matched case–control study using data from MarketScan databases for private health insurance and Medicaid from October 2015 to December 2018 estimated the association between TBI and suicidal ideation/attempts using a mediation approach. Individuals less than 65 years of age were included. Results In the Medicaid sample, psychiatric disorders mediated 22.4% of the total effect between TBI and suicidal ideation/attempt, while substance use disorders other than opioid use disorder mediated 7.47%. In the private health insurance sample, psychiatric disorders mediated 3.97% of the total effect, opioid use disorders mediated 2.08% of the total effect and sleep disorder mediated 1.25% of the total effect. Conclusions Mediators explained less than 30% of the relationship between TBI and suicidal ideation/attempt. Findings reinforce the importance of primary prevention of TBI and monitoring patients with a TBI for risk of suicide in the first 6–12 months following injury." @default.
• W4311621319 created "2022-12-27" @default.
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• W4311621319 date "2022-12-05" @default.
• W4311621319 modified "2023-09-27" @default.
• W4311621319 title "Association between traumatic brain injury and suicidality using a mediation approach and MarketScan" @default.
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• W4311621319 doi "https://doi.org/10.1136/ip-2022-044697" @default.
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• W4311621319 hasPublicationYear "2022" @default.
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