Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311679235> ?p ?o ?g. }
- W4311679235 abstract "Currently, little is known about the spatial distribution of white matter hyperintensities (WMH) in the brain of patients with Systemic Lupus erythematosus (SLE). Previous lesion markers, such as number and volume, ignore the strategic location of WMH. The goal of this work was to develop a fully-automated method to identify predominant patterns of WMH across WM tracts based on cluster analysis. A total of 221 SLE patients with and without neuropsychiatric symptoms from two different sites were included in this study. WMH segmentations and lesion locations were acquired automatically. Cluster analysis was performed on the WMH distribution in 20 WM tracts. Our pipeline identified five distinct clusters with predominant involvement of the forceps major, forceps minor, as well as right and left anterior thalamic radiations and the right inferior fronto-occipital fasciculus. The patterns of the affected WM tracts were consistent over the SLE subtypes and sites. Our approach revealed distinct and robust tract-based WMH patterns within SLE patients. This method could provide a basis, to link the location of WMH with clinical symptoms. Furthermore, it could be used for other diseases characterized by presence of WMH to investigate both the clinical relevance of WMH and underlying pathomechanism in the brain." @default.
- W4311679235 created "2022-12-28" @default.
- W4311679235 creator A5002886384 @default.
- W4311679235 creator A5002914719 @default.
- W4311679235 creator A5011506890 @default.
- W4311679235 creator A5028042265 @default.
- W4311679235 creator A5031844702 @default.
- W4311679235 creator A5031901743 @default.
- W4311679235 creator A5032906526 @default.
- W4311679235 creator A5039945921 @default.
- W4311679235 creator A5045361419 @default.
- W4311679235 creator A5048601066 @default.
- W4311679235 creator A5052842332 @default.
- W4311679235 creator A5057747297 @default.
- W4311679235 creator A5071141048 @default.
- W4311679235 creator A5084069057 @default.
- W4311679235 creator A5085996974 @default.
- W4311679235 date "2022-12-09" @default.
- W4311679235 modified "2023-09-30" @default.
- W4311679235 title "Tract-based white matter hyperintensity patterns in patients with systemic lupus erythematosus using an unsupervised machine learning approach" @default.
- W4311679235 cites W1587415643 @default.
- W4311679235 cites W1987971958 @default.
- W4311679235 cites W1993823752 @default.
- W4311679235 cites W2002922829 @default.
- W4311679235 cites W2016381774 @default.
- W4311679235 cites W2037320159 @default.
- W4311679235 cites W2049033093 @default.
- W4311679235 cites W2049791419 @default.
- W4311679235 cites W2065811496 @default.
- W4311679235 cites W2070527591 @default.
- W4311679235 cites W2074412614 @default.
- W4311679235 cites W2102848905 @default.
- W4311679235 cites W2104901197 @default.
- W4311679235 cites W2110793425 @default.
- W4311679235 cites W2122362881 @default.
- W4311679235 cites W2122477279 @default.
- W4311679235 cites W2132934085 @default.
- W4311679235 cites W2145034992 @default.
- W4311679235 cites W2155411482 @default.
- W4311679235 cites W2158742097 @default.
- W4311679235 cites W2159860161 @default.
- W4311679235 cites W2181523240 @default.
- W4311679235 cites W2254736880 @default.
- W4311679235 cites W2309455566 @default.
- W4311679235 cites W2329887752 @default.
- W4311679235 cites W2474737217 @default.
- W4311679235 cites W2496219973 @default.
- W4311679235 cites W2508455664 @default.
- W4311679235 cites W2529621925 @default.
- W4311679235 cites W2530972115 @default.
- W4311679235 cites W2561536790 @default.
- W4311679235 cites W2605926466 @default.
- W4311679235 cites W2681136189 @default.
- W4311679235 cites W2752465009 @default.
- W4311679235 cites W2765747267 @default.
- W4311679235 cites W2768007735 @default.
- W4311679235 cites W2785369339 @default.
- W4311679235 cites W2808843415 @default.
- W4311679235 cites W2895614609 @default.
- W4311679235 cites W2898210199 @default.
- W4311679235 cites W2903037149 @default.
- W4311679235 cites W2905134343 @default.
- W4311679235 cites W2985411656 @default.
- W4311679235 cites W2985849923 @default.
- W4311679235 cites W2997775611 @default.
- W4311679235 cites W3044700482 @default.
- W4311679235 cites W3094324035 @default.
- W4311679235 cites W3103145119 @default.
- W4311679235 cites W3116504338 @default.
- W4311679235 cites W3128482042 @default.
- W4311679235 cites W3137338797 @default.
- W4311679235 cites W3157566421 @default.
- W4311679235 cites W324822480 @default.
- W4311679235 doi "https://doi.org/10.1038/s41598-022-25990-w" @default.
- W4311679235 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36494508" @default.
- W4311679235 hasPublicationYear "2022" @default.
- W4311679235 type Work @default.
- W4311679235 citedByCount "1" @default.
- W4311679235 countsByYear W43116792352023 @default.
- W4311679235 crossrefType "journal-article" @default.
- W4311679235 hasAuthorship W4311679235A5002886384 @default.
- W4311679235 hasAuthorship W4311679235A5002914719 @default.
- W4311679235 hasAuthorship W4311679235A5011506890 @default.
- W4311679235 hasAuthorship W4311679235A5028042265 @default.
- W4311679235 hasAuthorship W4311679235A5031844702 @default.
- W4311679235 hasAuthorship W4311679235A5031901743 @default.
- W4311679235 hasAuthorship W4311679235A5032906526 @default.
- W4311679235 hasAuthorship W4311679235A5039945921 @default.
- W4311679235 hasAuthorship W4311679235A5045361419 @default.
- W4311679235 hasAuthorship W4311679235A5048601066 @default.
- W4311679235 hasAuthorship W4311679235A5052842332 @default.
- W4311679235 hasAuthorship W4311679235A5057747297 @default.
- W4311679235 hasAuthorship W4311679235A5071141048 @default.
- W4311679235 hasAuthorship W4311679235A5084069057 @default.
- W4311679235 hasAuthorship W4311679235A5085996974 @default.
- W4311679235 hasBestOaLocation W43116792351 @default.
- W4311679235 hasConcept C126838900 @default.
- W4311679235 hasConcept C142724271 @default.
- W4311679235 hasConcept C143409427 @default.
- W4311679235 hasConcept C146638467 @default.