Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311683698> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W4311683698 abstract "Abstract The functional analysis of protein nanopores is typically conducted in planar lipid bilayers or liposomes exploiting high-resolution but low-throughput electrical and optical read-outs. Yet, the reconstitution of protein nanopores in vitro still constitutes an empiric and low-throughput process. Addressing these limitations, nanopores can now be analysed using the functional nanopore (FuN) screen exploiting genetically-encoded fluorescent protein sensors that resolve distinct nanopore-dependent Ca 2+ in- and efflux patterns across the inner membrane of Escherichia coli . With a primary proof-of-concept established for the S 21 68 holin, and thereof based recombinant nanopore assemblies, the question arises to what extent alternative nanopores can be analysed with the FuN screen. Focussing on self-assembling membrane peptides, three sets of 13 different nanopores are assessed for their capacity to form nanopores in the context of the FuN screen. Nanopores tested comprise both natural and computationally-designed nanopores while a comparison with high-resolution biophysical studies provides an experimental benchmark for future studies." @default.
- W4311683698 created "2022-12-28" @default.
- W4311683698 creator A5002449664 @default.
- W4311683698 creator A5022570728 @default.
- W4311683698 creator A5026646364 @default.
- W4311683698 creator A5077825540 @default.
- W4311683698 date "2022-12-16" @default.
- W4311683698 modified "2023-10-12" @default.
- W4311683698 title "Systematic Evaluation of Self-Assembling Membrane Peptides to Form Nanopores in the context of the Functional Nanopore Screen" @default.
- W4311683698 cites W1971649883 @default.
- W4311683698 cites W2034070577 @default.
- W4311683698 cites W2047491625 @default.
- W4311683698 cites W2094207537 @default.
- W4311683698 cites W2198457157 @default.
- W4311683698 cites W2413962740 @default.
- W4311683698 cites W2549678059 @default.
- W4311683698 cites W2771999798 @default.
- W4311683698 cites W3153738495 @default.
- W4311683698 cites W3161348944 @default.
- W4311683698 cites W3211239537 @default.
- W4311683698 cites W3212148706 @default.
- W4311683698 doi "https://doi.org/10.1101/2022.12.16.520551" @default.
- W4311683698 hasPublicationYear "2022" @default.
- W4311683698 type Work @default.
- W4311683698 citedByCount "1" @default.
- W4311683698 countsByYear W43116836982023 @default.
- W4311683698 crossrefType "posted-content" @default.
- W4311683698 hasAuthorship W4311683698A5002449664 @default.
- W4311683698 hasAuthorship W4311683698A5022570728 @default.
- W4311683698 hasAuthorship W4311683698A5026646364 @default.
- W4311683698 hasAuthorship W4311683698A5077825540 @default.
- W4311683698 hasBestOaLocation W43116836981 @default.
- W4311683698 hasConcept C12554922 @default.
- W4311683698 hasConcept C141795571 @default.
- W4311683698 hasConcept C151730666 @default.
- W4311683698 hasConcept C171250308 @default.
- W4311683698 hasConcept C185592680 @default.
- W4311683698 hasConcept C192562407 @default.
- W4311683698 hasConcept C2779343474 @default.
- W4311683698 hasConcept C39944091 @default.
- W4311683698 hasConcept C41625074 @default.
- W4311683698 hasConcept C55493867 @default.
- W4311683698 hasConcept C86803240 @default.
- W4311683698 hasConceptScore W4311683698C12554922 @default.
- W4311683698 hasConceptScore W4311683698C141795571 @default.
- W4311683698 hasConceptScore W4311683698C151730666 @default.
- W4311683698 hasConceptScore W4311683698C171250308 @default.
- W4311683698 hasConceptScore W4311683698C185592680 @default.
- W4311683698 hasConceptScore W4311683698C192562407 @default.
- W4311683698 hasConceptScore W4311683698C2779343474 @default.
- W4311683698 hasConceptScore W4311683698C39944091 @default.
- W4311683698 hasConceptScore W4311683698C41625074 @default.
- W4311683698 hasConceptScore W4311683698C55493867 @default.
- W4311683698 hasConceptScore W4311683698C86803240 @default.
- W4311683698 hasLocation W43116836981 @default.
- W4311683698 hasOpenAccess W4311683698 @default.
- W4311683698 hasPrimaryLocation W43116836981 @default.
- W4311683698 hasRelatedWork W117144599 @default.
- W4311683698 hasRelatedWork W1995706914 @default.
- W4311683698 hasRelatedWork W2106847663 @default.
- W4311683698 hasRelatedWork W2161536338 @default.
- W4311683698 hasRelatedWork W2913871081 @default.
- W4311683698 hasRelatedWork W2921229526 @default.
- W4311683698 hasRelatedWork W2952109886 @default.
- W4311683698 hasRelatedWork W3025986755 @default.
- W4311683698 hasRelatedWork W3110055093 @default.
- W4311683698 hasRelatedWork W4247773486 @default.
- W4311683698 isParatext "false" @default.
- W4311683698 isRetracted "false" @default.
- W4311683698 workType "article" @default.