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- W4311684550 abstract "Abstract Introduction COVID-19 vaccines are considered safe and offer great protection from the virus. However, they can have several side effects including fever, fatigue, and local pain and swelling. Recently a trend in the drug adverse events reporting systems showed an increased number of female vaccine recipients having menstrual cycle abnormalities post-vaccination. Aim This study aimed to determine the association between menstrual cycle abnormalities and the COVID vaccines. Subjects and methods This is a cross-sectional study conducted among reproductive-age women aged between 18 and 50 years old. A self-administered questionnaire was distributed among women using an online survey. The questionnaire includes basic demographic characteristics, the number of received vaccine doses, the type of vaccines, and the changes in menstrual cycles after receiving the COVID-19 vaccine. Results 700 reproductive age women met the inclusion criteria. After the first dose there was a significant change in menstrual cycle regularity P-value 0.009 (95% confidence interval 0.402-0.881) and odds ratio of (0.595). However, there was no significant change after the second and third dose p-value 0.065 and 0.055 respectively. The data also indicated a significant change in the menses flow; P-value (<0.001), with more women experiencing a reduction or increase in their period flow. Conclusion This study identifies a possible association between menstrual cycle abnormalities and COVID-19 vaccination. This was noted most after the first dose. Menstrual cycle abnormalities were in the form of changes in cycle length, duration of bleeding, premenstrual symptoms, and having missed periods. Menstrual changes are not uncommon but are transient and should not be alarming for women yet awareness about this experience is an instrumental factor to build trust in the COVID-19 vaccine." @default.
- W4311684550 created "2022-12-28" @default.
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- W4311684550 date "2022-12-16" @default.
- W4311684550 modified "2023-10-10" @default.
- W4311684550 title "The association between menstrual cycle abnormalities and the COVID-19 vaccine" @default.
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- W4311684550 doi "https://doi.org/10.21203/rs.3.rs-2330401/v1" @default.
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