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- W4311702511 abstract "Recently shown to meet regulatory requirements for safety assessment, high-performance thin-layer chromatography hyphenated with the SOS-Umu-C bioassay and S9 metabolization was applied to various food contact material prototypes, such as paper, plastic and coating samples. Studying reversed versus normal phase separation and piezoelectrical spraying versus syringe dosage of the bioassay, 14 genotoxic bands were detected. Three epoxides of linolenic acid were identified as genotoxic candidates in the paper migrate by heated electrospray and atmospheric pressure chemical ionization high-resolution mass spectrometry. These were confirmed by co-chromatography with linolenic acid epoxides. Comparatively poorer detection limits of in vitro microtiter plate bioassays and opposing effects/signal responses in the sample explained false-negative responses for paper migrate. However, the in vitro SOS-Umu-C microtiter plate bioassay confirmed the genotoxicity of a simulated linolenic acid epoxidation, and after sample concentration, the paper migrate mutagenicity was confirmed by the Ames-MPF™ bioassay." @default.
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- W4311702511 date "2023-05-01" @default.
- W4311702511 modified "2023-09-23" @default.
- W4311702511 title "A reply to the Letter to the Editor of Moškrič et al. entitled “A comment on the paper from Utzeri et al. (2022) “Entomological authentication of honey based on a DNA method that distinguishes Apis mellifera mitochondrial C mitotypes: Application to honey produced by A. m. ligustica and A. m. carnica, Food control, Volume 121, March 2021, 107626”." @default.
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- W4311702511 doi "https://doi.org/10.1016/j.foodcont.2022.109570" @default.
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