Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311752065> ?p ?o ?g. }
- W4311752065 endingPage "130612" @default.
- W4311752065 startingPage "130612" @default.
- W4311752065 abstract "Noninvasively imaging mercury poisoning in living organisms is critical to understanding its toxicity and treatments. Especially, simultaneous fluorescence imaging of Hg2+ and MeHg+in vivo is helpful to disclose the mysteries of mercury poisoning. The key limitation for mercury imaging in vivo is the low imaging signal-to-background ratio (SBR) and limited imaging depth, which may result in unreliable detection results. Here, we designed and prepared a near-infrared II (NIR II) emissive probe, NIR-Rh-MS, leveraging the spirolactam ring-open tactic of xanthene dyes for in situ visualization of mercury toxicity in mice. The probe produces a marked fluorescence signal at 1015 nm and displays good linear responses to Hg2+ and MeHg+ with excellent sensitivity, respectively. The penetration experiments elucidate that the activated NIR-II fluorescence signal of the probe penetrates to a depth of up to 7 mm in simulated tissues. Impressively, the probe can monitor the toxicity of Hg2+ in mouse livers and the accumulation of MeHg+ in mouse brains via intravital NIR-II imaging for the first time. Thus, we believe that detecting Hg2+ and MeHg+ in different organs with a single NIR-II fluorescence probe in mice would assuredly advance the toxicologic study of mercury poisoning in vivo." @default.
- W4311752065 created "2022-12-28" @default.
- W4311752065 creator A5007054845 @default.
- W4311752065 creator A5024792434 @default.
- W4311752065 creator A5046847266 @default.
- W4311752065 creator A5056681604 @default.
- W4311752065 creator A5058196311 @default.
- W4311752065 creator A5061971945 @default.
- W4311752065 date "2023-03-01" @default.
- W4311752065 modified "2023-10-16" @default.
- W4311752065 title "Monitoring Hg2+ and MeHg+ poisoning in living body with an activatable near-infrared II fluorescence probe" @default.
- W4311752065 cites W1166288945 @default.
- W4311752065 cites W1988155544 @default.
- W4311752065 cites W1991950902 @default.
- W4311752065 cites W2004999616 @default.
- W4311752065 cites W2019471453 @default.
- W4311752065 cites W2028713145 @default.
- W4311752065 cites W2063155405 @default.
- W4311752065 cites W2086202572 @default.
- W4311752065 cites W2117082119 @default.
- W4311752065 cites W2149343375 @default.
- W4311752065 cites W2263207418 @default.
- W4311752065 cites W2322384091 @default.
- W4311752065 cites W2334989577 @default.
- W4311752065 cites W2552356061 @default.
- W4311752065 cites W2607851096 @default.
- W4311752065 cites W2737186440 @default.
- W4311752065 cites W2751376138 @default.
- W4311752065 cites W2784705588 @default.
- W4311752065 cites W2884172015 @default.
- W4311752065 cites W2913004370 @default.
- W4311752065 cites W2919845680 @default.
- W4311752065 cites W2921220156 @default.
- W4311752065 cites W2941489351 @default.
- W4311752065 cites W2950294497 @default.
- W4311752065 cites W2952472280 @default.
- W4311752065 cites W3000195331 @default.
- W4311752065 cites W3013461710 @default.
- W4311752065 cites W3014281600 @default.
- W4311752065 cites W3034623023 @default.
- W4311752065 cites W3036418258 @default.
- W4311752065 cites W3081288643 @default.
- W4311752065 cites W3085153653 @default.
- W4311752065 cites W3086590916 @default.
- W4311752065 cites W3086680449 @default.
- W4311752065 cites W3089720120 @default.
- W4311752065 cites W3101852403 @default.
- W4311752065 cites W3106211977 @default.
- W4311752065 cites W3111029008 @default.
- W4311752065 cites W3127415754 @default.
- W4311752065 cites W3128399770 @default.
- W4311752065 cites W3144435069 @default.
- W4311752065 cites W3182917748 @default.
- W4311752065 cites W3205765004 @default.
- W4311752065 cites W3207220360 @default.
- W4311752065 cites W3214330881 @default.
- W4311752065 cites W4200233375 @default.
- W4311752065 cites W4200555796 @default.
- W4311752065 cites W4200587062 @default.
- W4311752065 cites W4207009941 @default.
- W4311752065 cites W4212856156 @default.
- W4311752065 cites W4220682673 @default.
- W4311752065 cites W4280543397 @default.
- W4311752065 cites W4288046055 @default.
- W4311752065 cites W4290567131 @default.
- W4311752065 cites W4297855215 @default.
- W4311752065 cites W4308374388 @default.
- W4311752065 doi "https://doi.org/10.1016/j.jhazmat.2022.130612" @default.
- W4311752065 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37056002" @default.
- W4311752065 hasPublicationYear "2023" @default.
- W4311752065 type Work @default.
- W4311752065 citedByCount "6" @default.
- W4311752065 countsByYear W43117520652023 @default.
- W4311752065 crossrefType "journal-article" @default.
- W4311752065 hasAuthorship W4311752065A5007054845 @default.
- W4311752065 hasAuthorship W4311752065A5024792434 @default.
- W4311752065 hasAuthorship W4311752065A5046847266 @default.
- W4311752065 hasAuthorship W4311752065A5056681604 @default.
- W4311752065 hasAuthorship W4311752065A5058196311 @default.
- W4311752065 hasAuthorship W4311752065A5061971945 @default.
- W4311752065 hasConcept C120665830 @default.
- W4311752065 hasConcept C121332964 @default.
- W4311752065 hasConcept C12554922 @default.
- W4311752065 hasConcept C150903083 @default.
- W4311752065 hasConcept C178790620 @default.
- W4311752065 hasConcept C185592680 @default.
- W4311752065 hasConcept C199360897 @default.
- W4311752065 hasConcept C207001950 @default.
- W4311752065 hasConcept C2777777548 @default.
- W4311752065 hasConcept C29331040 @default.
- W4311752065 hasConcept C29730261 @default.
- W4311752065 hasConcept C41008148 @default.
- W4311752065 hasConcept C43571822 @default.
- W4311752065 hasConcept C57477423 @default.
- W4311752065 hasConcept C86803240 @default.
- W4311752065 hasConcept C91881484 @default.
- W4311752065 hasConceptScore W4311752065C120665830 @default.
- W4311752065 hasConceptScore W4311752065C121332964 @default.