FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311752103> ?p ?o ?g. }

• W4311752103 abstract "Abstract A 7-year-old (y.o.) boy was referred to our center for a specialist evaluation due to alteration of the ventricular repolarization in the anterior and lateral lead on the electrocardiogram at medical evaluation for physical activity. The child was totally asymptomatic, with normal growth and unremarkable past medical history. The physical examination revealed only S4 and a minimal apical systolic murmur. Transthoracic echocardiogram demonstrated a mildly dilated left ventricle (LV) and normal left ventricular ejection fraction. Strain pattern of basal-medium segments of lateral wall was reduced. Right coronary artery (RCA) appeared dilatated and the left coronary artery (LCA) showed an inverse flow at Doppler evaluation. Findings were suspicious for ALCAPA diagnosis (Anomalous Left Coronary Artery Arising from the Pulmonary Artery); a rare congenital heart disease that, if not treated, leads to death in 90% of cases during first year of life. Adult type of ALCAPA (adolescence-60 y.o) is even more rare and can cause heart failure due to a dilatative cardiomyopathy, chronic cardiac ischemia and, in 80-90% of cases, sudden cardiac death. We performed a coronary angiography that confirmed the anomalous origin of LCA from the pulmonary artery. The RCA was dominant, enlarged and supplied an important collateral flow for LCA. Coronary angiography is indicated not only for diagnosis confirmation, but also for coronary tree demonstration, especially in adult type of ALCAPA, because of the presence of not rare anomalies or “adaptation” of peripheral coronary circulation. All these features are important positive prognostic factors that enable survival beyond infancy. LCA ostium stenosis or bronchial artery collateral vessels are also common but weren't seen in this case. In adult type of ALCAPA surgery is usually indicated at the time of diagnosis, so a coronary button transfer and pulmonary Valsalva sinus reconstruction with autologous pericardial patch were performed. This is the preferred surgical technique in adult patients as it is the most anatomic correction. Since before hospitalization heart failure therapy with betablocker was introduced and after surgery aspirin therapy was started too. Post-surgery transthoracic echocardiogram highlighted a moderate pericardial effusion without haemodynamic impact and a pleural effusion, so an anti-inflammatory therapy with ibuprofen, cortisone and then colchicine was started. After discharge anti-inflammatory therapy was under-titrated until suspension based on gradual reduction of pericardial and pleural effusion. Patient was always free of symptoms and with good performance status. ALCAPA or Bland–White–Garland syndrome is an uncommon congenital heart disease. The presence of adequate collateral circulation between RCA and LCA allows to survive beyond infancy (adult type). We described a case of early diagnosis of adult type of ALCAPA in asymptomatic child thanks to a careful examination of basal electrocardiogram for evaluation of non-competitive sport practice." @default.
• W4311752103 created "2022-12-28" @default.
• W4311752103 creator A5035051569 @default.
• W4311752103 creator A5039528513 @default.
• W4311752103 creator A5041457505 @default.
• W4311752103 creator A5041577913 @default.
• W4311752103 creator A5065724585 @default.
• W4311752103 creator A5068029489 @default.
• W4311752103 creator A5070056074 @default.
• W4311752103 creator A5076198451 @default.
• W4311752103 date "2022-12-14" @default.
• W4311752103 modified "2023-10-11" @default.
• W4311752103 title "278 A CASE OF ACCIDENTAL DIAGNOSIS OF ALCAPA SYNDROME IN ASYMPTOMATIC CHILD" @default.
• W4311752103 doi "https://doi.org/10.1093/eurheartjsupp/suac121.279" @default.
• W4311752103 hasPublicationYear "2022" @default.
• W4311752103 type Work @default.
• W4311752103 citedByCount "0" @default.
• W4311752103 crossrefType "journal-article" @default.
• W4311752103 hasAuthorship W4311752103A5035051569 @default.
• W4311752103 hasAuthorship W4311752103A5039528513 @default.
• W4311752103 hasAuthorship W4311752103A5041457505 @default.
• W4311752103 hasAuthorship W4311752103A5041577913 @default.
• W4311752103 hasAuthorship W4311752103A5065724585 @default.
• W4311752103 hasAuthorship W4311752103A5068029489 @default.
• W4311752103 hasAuthorship W4311752103A5070056074 @default.
• W4311752103 hasAuthorship W4311752103A5076198451 @default.
• W4311752103 hasBestOaLocation W43117521031 @default.
• W4311752103 hasConcept C126322002 @default.
• W4311752103 hasConcept C164705383 @default.
• W4311752103 hasConcept C2775935837 @default.
• W4311752103 hasConcept C2776820930 @default.
• W4311752103 hasConcept C2777910003 @default.
• W4311752103 hasConcept C2778088351 @default.
• W4311752103 hasConcept C2778198053 @default.
• W4311752103 hasConcept C2778797674 @default.
• W4311752103 hasConcept C2778921608 @default.
• W4311752103 hasConcept C2780231137 @default.
• W4311752103 hasConcept C2780940725 @default.
• W4311752103 hasConcept C2993353509 @default.
• W4311752103 hasConcept C3019004856 @default.
• W4311752103 hasConcept C500558357 @default.
• W4311752103 hasConcept C71924100 @default.
• W4311752103 hasConcept C78085059 @default.
• W4311752103 hasConceptScore W4311752103C126322002 @default.
• W4311752103 hasConceptScore W4311752103C164705383 @default.
• W4311752103 hasConceptScore W4311752103C2775935837 @default.
• W4311752103 hasConceptScore W4311752103C2776820930 @default.
• W4311752103 hasConceptScore W4311752103C2777910003 @default.
• W4311752103 hasConceptScore W4311752103C2778088351 @default.
• W4311752103 hasConceptScore W4311752103C2778198053 @default.
• W4311752103 hasConceptScore W4311752103C2778797674 @default.
• W4311752103 hasConceptScore W4311752103C2778921608 @default.
• W4311752103 hasConceptScore W4311752103C2780231137 @default.
• W4311752103 hasConceptScore W4311752103C2780940725 @default.
• W4311752103 hasConceptScore W4311752103C2993353509 @default.
• W4311752103 hasConceptScore W4311752103C3019004856 @default.
• W4311752103 hasConceptScore W4311752103C500558357 @default.
• W4311752103 hasConceptScore W4311752103C71924100 @default.
• W4311752103 hasConceptScore W4311752103C78085059 @default.
• W4311752103 hasIssue "Supplement_K" @default.
• W4311752103 hasLocation W43117521031 @default.
• W4311752103 hasOpenAccess W4311752103 @default.
• W4311752103 hasPrimaryLocation W43117521031 @default.
• W4311752103 hasRelatedWork W2086120745 @default.
• W4311752103 hasRelatedWork W2099685164 @default.
• W4311752103 hasRelatedWork W2372345665 @default.
• W4311752103 hasRelatedWork W2756477800 @default.
• W4311752103 hasRelatedWork W2979481551 @default.
• W4311752103 hasRelatedWork W2985782568 @default.
• W4311752103 hasRelatedWork W3204940653 @default.
• W4311752103 hasRelatedWork W4280489811 @default.
• W4311752103 hasRelatedWork W4308773024 @default.
• W4311752103 hasRelatedWork W4367060219 @default.
• W4311752103 hasVolume "24" @default.
• W4311752103 isParatext "false" @default.
• W4311752103 isRetracted "false" @default.
• W4311752103 workType "article" @default.