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- W4311773087 abstract "High-dose melphalan followed by autologous haematopoietic stem-cell transplantation (HSCT) has been the standard-of-care in multiple myeloma treatment for the past 30 years. However, with increasingly potent triplet regimens leading to improved response rates after induction, the need for autologous HSCT is increasingly questioned. Its role has been evaluated in four important randomised clinical trials. In the EMN02/HO95 study, induction therapy consisted of bortezomib–cyclophosphamide–dexamethasone before randomisation to either bortezomib–melphalan–prednisone or autologous HSCT." @default.
- W4311773087 created "2022-12-28" @default.
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- W4311773087 date "2023-02-01" @default.
- W4311773087 modified "2023-09-26" @default.
- W4311773087 title "Upfront autologous transplantation still improving outcomes in patients with multiple myeloma" @default.
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- W4311773087 doi "https://doi.org/10.1016/s2352-3026(22)00360-x" @default.
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