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- W4311822997 abstract "Imidazoles are among the most important pharmacophores in medicinal chemistry. Herein we report a tandem protocol for the synthesis of highly substituted imidazoles through Pummerer-like rearrangement induced cascade reactions including two carbon–nitrogen bond formations, and concomitant aromatization under mild reaction conditions. This procedure gives imidazole derivatives bearing numerous functional groups and could be used for modifying natural products as well as pharmaceuticals." @default.
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- W4311822997 date "2022-12-16" @default.
- W4311822997 modified "2023-10-17" @default.
- W4311822997 title "Pummerer-like Rearrangement Induced Cascade Reactions: Synthesis of Highly Functionalized Imidazoles" @default.
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- W4311822997 doi "https://doi.org/10.1021/acs.joc.2c02411" @default.
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