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• W4311853230 abstract "Osteoarthritis of the equine distal interphalangeal joint is a common cause of lameness. MicroRNAs from biofluids are promising biomarkers and therapeutic candidates. Synovial fluid samples from horses with mild and severe equine distal interphalangeal joint osteoarthritis were submitted for small RNA sequencing. The results demonstrated that miR-92a was downregulated in equine synovial fluid from horses with severe osteoarthritis and there was a significant increase in COMP, COL1A2, RUNX2 and SOX9 following miR-92a mimic treatment of equine chondrocytes in monolayer culture. This is the first equine study to evaluate the role of miR-92a in osteoarthritic chondrocytes in vitro." @default.
• W4311853230 created "2023-01-01" @default.
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• W4311853230 date "2022-12-08" @default.
• W4311853230 modified "2023-10-10" @default.
• W4311853230 title "Investigation of MicroRNA Biomarkers in Equine Distal Interphalangeal Joint Osteoarthritis" @default.
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• W4311853230 doi "https://doi.org/10.3390/ijms232415526" @default.
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