Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311881294> ?p ?o ?g. }
- W4311881294 abstract "We report here the development of an electrochemical cell-free biosensor for antibody detection directly in complex sample matrices with high sensitivity and specificity that is particularly suitable for point-of-care applications. The approach is based on the use of programmable antigen-conjugated gene circuits that, upon recognition of a specific target antibody, trigger the cell-free transcription of an RNA sequence that can be consequently detected using a redox-modified probe strand immobilized to a disposable electrode. The platform couples the features of high sensitivity and specificity of cell-free systems and the strength of cost-effectiveness and possible miniaturization provided by the electrochemical detection. We demonstrate the sensitive, specific, selective, and multiplexed detection of three different antibodies, including the clinically-relevant Anti-HA antibody." @default.
- W4311881294 created "2023-01-02" @default.
- W4311881294 creator A5018935401 @default.
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- W4311881294 date "2023-01-12" @default.
- W4311881294 modified "2023-10-11" @default.
- W4311881294 title "Electrochemical Cell‐Free Biosensors for Antibody Detection" @default.
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- W4311881294 doi "https://doi.org/10.1002/anie.202216512" @default.
- W4311881294 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36533529" @default.
- W4311881294 hasPublicationYear "2023" @default.
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