FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311883456> ?p ?o ?g. }

• W4311883456 endingPage "620" @default.
• W4311883456 startingPage "613" @default.
• W4311883456 abstract "Computational models of rodent physiology implicate hippocampal theta as a key modulator of learning and memory (Buzsáki and Moser, 2013; Lisman and Jensen, 2013), yet human hippocampal recordings have shown divergent theta correlates of memory formation. Herweg et al. (2020) suggest that decreases in memory-related broadband power mask narrowband theta increases. Their survey also notes that the theta oscillations appear most prominently in contrasts that isolate memory retrieval processes and when aggregating signals across large brain regions. We evaluate these hypotheses by analyzing human hippocampal recordings captured as 162 neurosurgical patients (n = 86 female) performed a free recall task. Using the Irregular-Resampling Auto-Spectral Analysis (IRASA) to separate broad and narrowband components of the field potential, we show that (1) broadband and narrowband components of theta exhibit opposite effects, with broadband signals decreasing and narrowband theta increasing during successful encoding; (2) whereas low-frequency theta oscillations increase before successful recall, higher-frequency theta and alpha oscillations decrease, masking the positive effect of theta when aggregating across the full band; and (3) the effects of theta on memory encoding and retrieval do not differ between reference schemes that accentuate local signals (bipolar) and those that aggregate signals globally (whole-brain average). In line with computational models that ascribe a fundamental role for hippocampal theta in memory, our large-scale study of human hippocampal recordings shows that 3-4 Hz theta oscillations reliably increase during successful memory encoding and before spontaneous recall of previously studied items.SIGNIFICANCE STATEMENT Analyzing recordings from 162 participants, we resolve a long-standing question regarding the role of hippocampal theta oscillations in the formation and retrieval of episodic memories. We show that broadband spectral changes confound estimates of narrowband theta activity, thereby accounting for inconsistent results in the literature. After accounting for broadband effects, we find that increased theta activity marks successful encoding and retrieval of episodic memories, supporting rodent models that ascribe a key role for hippocampal theta in memory function." @default.
• W4311883456 created "2023-01-02" @default.
• W4311883456 creator A5000983569 @default.
• W4311883456 creator A5047355393 @default.
• W4311883456 creator A5064010199 @default.
• W4311883456 date "2022-12-08" @default.
• W4311883456 modified "2023-10-10" @default.
• W4311883456 title "Hippocampal Theta and Episodic Memory" @default.
• W4311883456 cites W1563625862 @default.
• W4311883456 cites W1739514309 @default.
• W4311883456 cites W1857076555 @default.
• W4311883456 cites W1927777346 @default.
• W4311883456 cites W1951724000 @default.
• W4311883456 cites W1969724616 @default.
• W4311883456 cites W1970928383 @default.
• W4311883456 cites W1974454036 @default.
• W4311883456 cites W1976804176 @default.
• W4311883456 cites W1986971727 @default.
• W4311883456 cites W2004725045 @default.
• W4311883456 cites W2010254880 @default.
• W4311883456 cites W2025180344 @default.
• W4311883456 cites W2025346474 @default.
• W4311883456 cites W2046913658 @default.
• W4311883456 cites W2052515926 @default.
• W4311883456 cites W2059577564 @default.
• W4311883456 cites W2059893887 @default.
• W4311883456 cites W2059958563 @default.
• W4311883456 cites W2072843066 @default.
• W4311883456 cites W2104141548 @default.
• W4311883456 cites W2105496689 @default.
• W4311883456 cites W2116200167 @default.
• W4311883456 cites W2119572534 @default.
• W4311883456 cites W2123565526 @default.
• W4311883456 cites W2133442910 @default.
• W4311883456 cites W2134609261 @default.
• W4311883456 cites W2141558799 @default.
• W4311883456 cites W2142864695 @default.
• W4311883456 cites W2146677108 @default.
• W4311883456 cites W2150750597 @default.
• W4311883456 cites W2160712927 @default.
• W4311883456 cites W2161248279 @default.
• W4311883456 cites W2228094914 @default.
• W4311883456 cites W2269315604 @default.
• W4311883456 cites W2310622091 @default.
• W4311883456 cites W2410446460 @default.
• W4311883456 cites W2489876402 @default.
• W4311883456 cites W2597768581 @default.
• W4311883456 cites W2607293739 @default.
• W4311883456 cites W2625974073 @default.
• W4311883456 cites W2788344808 @default.
• W4311883456 cites W2902529948 @default.
• W4311883456 cites W2924835522 @default.
• W4311883456 cites W2964851717 @default.
• W4311883456 cites W2965216914 @default.
• W4311883456 cites W2977551935 @default.
• W4311883456 cites W2986140611 @default.
• W4311883456 cites W3004996877 @default.
• W4311883456 cites W3110151578 @default.
• W4311883456 cites W3198118524 @default.
• W4311883456 cites W4282959130 @default.
• W4311883456 cites W4295102392 @default.
• W4311883456 cites W4297752423 @default.
• W4311883456 doi "https://doi.org/10.1523/jneurosci.1045-22.2022" @default.
• W4311883456 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36639900" @default.
• W4311883456 hasPublicationYear "2022" @default.
• W4311883456 type Work @default.
• W4311883456 citedByCount "4" @default.
• W4311883456 countsByYear W43118834562023 @default.
• W4311883456 crossrefType "journal-article" @default.
• W4311883456 hasAuthorship W4311883456A5000983569 @default.
• W4311883456 hasAuthorship W4311883456A5047355393 @default.
• W4311883456 hasAuthorship W4311883456A5064010199 @default.
• W4311883456 hasBestOaLocation W43118834561 @default.
• W4311883456 hasConcept C100660578 @default.
• W4311883456 hasConcept C117838684 @default.
• W4311883456 hasConcept C120665830 @default.
• W4311883456 hasConcept C121332964 @default.
• W4311883456 hasConcept C125411270 @default.
• W4311883456 hasConcept C148762608 @default.
• W4311883456 hasConcept C15744967 @default.
• W4311883456 hasConcept C169760540 @default.
• W4311883456 hasConcept C169900460 @default.
• W4311883456 hasConcept C180747234 @default.
• W4311883456 hasConcept C2776096036 @default.
• W4311883456 hasConcept C2781161787 @default.
• W4311883456 hasConcept C88576662 @default.
• W4311883456 hasConceptScore W4311883456C100660578 @default.
• W4311883456 hasConceptScore W4311883456C117838684 @default.
• W4311883456 hasConceptScore W4311883456C120665830 @default.
• W4311883456 hasConceptScore W4311883456C121332964 @default.
• W4311883456 hasConceptScore W4311883456C125411270 @default.
• W4311883456 hasConceptScore W4311883456C148762608 @default.
• W4311883456 hasConceptScore W4311883456C15744967 @default.
• W4311883456 hasConceptScore W4311883456C169760540 @default.
• W4311883456 hasConceptScore W4311883456C169900460 @default.
• W4311883456 hasConceptScore W4311883456C180747234 @default.
• W4311883456 hasConceptScore W4311883456C2776096036 @default.
• W4311883456 hasConceptScore W4311883456C2781161787 @default.

• next