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• W4311887599 abstract "Homeobox genes encode transcription factors with essential roles in patterning and cell fate in developing animal embryos. Many homeobox genes, including Hox and NK genes, are arranged in gene clusters, a feature likely related to transcriptional control. Sparse taxon sampling and fragmentary genome assemblies mean that little is known about the dynamics of homeobox gene evolution across Lepidoptera or about how changes in homeobox gene number and organization relate to diversity in this large order of insects. Here we analyze an extensive data set of high-quality genomes to characterize the number and organization of all homeobox genes in 123 species of Lepidoptera from 23 taxonomic families. We find most Lepidoptera have around 100 homeobox loci, including an unusual Hox gene cluster in which the lab gene is repositioned and the ro gene is next to pb A topologically associating domain spans much of the gene cluster, suggesting deep regulatory conservation of the Hox cluster arrangement in this insect order. Most Lepidoptera have four Shx genes, divergent zen-derived loci, but these loci underwent dramatic duplication in several lineages, with some moths having over 165 homeobox loci in the Hox gene cluster; this expansion is associated with local LINE element density. In contrast, the NK gene cluster content is more stable, although there are differences in organization compared with other insects, as well as major rearrangements within butterflies. Our analysis represents the first description of homeobox gene content across the order Lepidoptera, exemplifying the potential of newly generated genome assemblies for understanding genome and gene family evolution." @default.
• W4311887599 created "2023-01-02" @default.
• W4311887599 creator A5002111430 @default.
• W4311887599 creator A5016216861 @default.
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• W4311887599 creator A5033463535 @default.
• W4311887599 creator A5077529047 @default.
• W4311887599 creator A5090035044 @default.
• W4311887599 date "2022-12-08" @default.
• W4311887599 modified "2023-10-09" @default.
• W4311887599 title "Diversity, duplication, and genomic organization of homeobox genes in Lepidoptera" @default.
• W4311887599 cites W1482190741 @default.
• W4311887599 cites W1965178844 @default.
• W4311887599 cites W1972453970 @default.
• W4311887599 cites W1972708928 @default.
• W4311887599 cites W1974250511 @default.
• W4311887599 cites W1985348819 @default.
• W4311887599 cites W1995775187 @default.
• W4311887599 cites W2002383724 @default.
• W4311887599 cites W2006096663 @default.
• W4311887599 cites W2006788765 @default.
• W4311887599 cites W2009851083 @default.
• W4311887599 cites W2010710876 @default.
• W4311887599 cites W2020903222 @default.
• W4311887599 cites W2028098940 @default.
• W4311887599 cites W2035397219 @default.
• W4311887599 cites W2043422388 @default.
• W4311887599 cites W2044082480 @default.
• W4311887599 cites W2050195688 @default.
• W4311887599 cites W2056482755 @default.
• W4311887599 cites W2059768259 @default.
• W4311887599 cites W2062116795 @default.
• W4311887599 cites W2070933613 @default.
• W4311887599 cites W2071905527 @default.
• W4311887599 cites W2072818545 @default.
• W4311887599 cites W2087073913 @default.
• W4311887599 cites W2093755714 @default.
• W4311887599 cites W2096549168 @default.
• W4311887599 cites W2098668417 @default.
• W4311887599 cites W2102502076 @default.
• W4311887599 cites W2102573471 @default.
• W4311887599 cites W2106788283 @default.
• W4311887599 cites W2111453524 @default.
• W4311887599 cites W2111647009 @default.
• W4311887599 cites W2116509508 @default.
• W4311887599 cites W2118172195 @default.
• W4311887599 cites W2118553987 @default.
• W4311887599 cites W2124573618 @default.
• W4311887599 cites W2126419817 @default.
• W4311887599 cites W2131101891 @default.
• W4311887599 cites W2131416442 @default.
• W4311887599 cites W2132348979 @default.
• W4311887599 cites W2135271831 @default.
• W4311887599 cites W2135740919 @default.
• W4311887599 cites W2142475839 @default.
• W4311887599 cites W2156969576 @default.
• W4311887599 cites W2166711485 @default.
• W4311887599 cites W2172400873 @default.
• W4311887599 cites W2176692887 @default.
• W4311887599 cites W2224947686 @default.
• W4311887599 cites W2323326409 @default.
• W4311887599 cites W2340667260 @default.
• W4311887599 cites W2344773802 @default.
• W4311887599 cites W2345404113 @default.
• W4311887599 cites W2394666260 @default.
• W4311887599 cites W2506612908 @default.
• W4311887599 cites W2513727910 @default.
• W4311887599 cites W2530810534 @default.
• W4311887599 cites W2561817635 @default.
• W4311887599 cites W2596601694 @default.
• W4311887599 cites W2614081736 @default.
• W4311887599 cites W2759996086 @default.
• W4311887599 cites W2792493536 @default.
• W4311887599 cites W2801361050 @default.
• W4311887599 cites W2809684884 @default.
• W4311887599 cites W2907366436 @default.
• W4311887599 cites W2937151182 @default.
• W4311887599 cites W2938574745 @default.
• W4311887599 cites W2945038365 @default.
• W4311887599 cites W2950454586 @default.
• W4311887599 cites W2950954328 @default.
• W4311887599 cites W2951206358 @default.
• W4311887599 cites W2951322997 @default.
• W4311887599 cites W2951521970 @default.
• W4311887599 cites W2965645356 @default.
• W4311887599 cites W2970147901 @default.
• W4311887599 cites W2980958588 @default.
• W4311887599 cites W2982062771 @default.
• W4311887599 cites W3005235420 @default.
• W4311887599 cites W3017049640 @default.
• W4311887599 cites W3036185121 @default.
• W4311887599 cites W3103145119 @default.
• W4311887599 cites W3104413386 @default.
• W4311887599 cites W3126707101 @default.
• W4311887599 cites W3126870464 @default.
• W4311887599 cites W3127314690 @default.
• W4311887599 cites W3176890960 @default.
• W4311887599 cites W3186309583 @default.

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