FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311890042> ?p ?o ?g. }

• W4311890042 endingPage "45" @default.
• W4311890042 startingPage "38" @default.
• W4311890042 abstract "&#x0D; &#x0D; &#x0D; &#x0D; Background. The pathophysiology of gestational diabetes, which is related to abnormal gluocose tolerance and hyperinsulinaemia, renders standard fetal monitoring models ineffective, insufficient and inappropriate, as these models revolve around detecting and prognosticating on placenta-mediated disease rather than increased metabolic rates due to hyperinsulinaemia, functional hypoxia and ischaemic trophoblastic thresholds. To improve perinatal morbidity and mortality in gestational diabetes, there is therefore a need to introduce new prognostic parameters and scoring systems.&#x0D; Objectives. A proposed risk scoring system has been developed, based on our previous studies, to risk-categorise patients with gestational diabetes in terms of fetal outcome in view of the fact that the pathophysiology of gestational diabetes is not recognised by standard monitoring models, which revolve around placental insufficiency rather than metabolic anomalies.Methods. Patients with diabetes from four case-control studies were combined to form a total sample of 159 cases for validation of the risk scoring system. Univariate logistic regression analysis was used to assess the effect of individual risk factors with proposed cut-offs on adverse pregnancy outcome. The diagnostic accuracy of the total summative score was assessed by computing the area under the receiver operating characteristic (ROC) curve.&#x0D; Results. Four potential parameters were identified to risk-categorise fetuses in a pregnancy complicated by gestational diabetes, i.e. the myocardial performance index (MPI), the E/A ratio (early diastolic filling/late diastolic filling, a marker of diastolic dysfunction), increasing fetal weight (macrosomia), and an increased amniotic fluid index. The total score, obtained by summation of the composite scores for these parameters, ranged from 0 to 11. The total score performed as an excellent predictor of adverse outcome, evidenced by an ROC area under the curve of 0.94. A cut-point of 6 on the score confers a sensitivity of 84.2% and specificity of 90.2% for predicting adverse outcome.&#x0D; Conclusion. To our knowledge, this is the first gestational diabetes scoring system proposed to predict an adverse outcome.&#x0D; &#x0D; &#x0D; &#x0D;" @default.
• W4311890042 created "2023-01-02" @default.
• W4311890042 creator A5042620576 @default.
• W4311890042 creator A5074366172 @default.
• W4311890042 date "2022-11-26" @default.
• W4311890042 modified "2023-10-14" @default.
• W4311890042 title "A proposed fetal risk scoring system for gestational diabetes to assist in optimising timing of delivery" @default.
• W4311890042 cites W1978212038 @default.
• W4311890042 cites W1979560458 @default.
• W4311890042 cites W1980682170 @default.
• W4311890042 cites W1993129936 @default.
• W4311890042 cites W1999835825 @default.
• W4311890042 cites W1999934266 @default.
• W4311890042 cites W2031114174 @default.
• W4311890042 cites W2035716102 @default.
• W4311890042 cites W2039503336 @default.
• W4311890042 cites W2040521411 @default.
• W4311890042 cites W2050868673 @default.
• W4311890042 cites W2063091321 @default.
• W4311890042 cites W2064907105 @default.
• W4311890042 cites W2069394555 @default.
• W4311890042 cites W2086981540 @default.
• W4311890042 cites W2125044858 @default.
• W4311890042 cites W2134293572 @default.
• W4311890042 cites W2142536892 @default.
• W4311890042 cites W2619105265 @default.
• W4311890042 cites W2964110336 @default.
• W4311890042 cites W3012456625 @default.
• W4311890042 cites W3036490824 @default.
• W4311890042 cites W4241280155 @default.
• W4311890042 cites W4242469286 @default.
• W4311890042 doi "https://doi.org/10.7196/sajog.2022.v28i2.2069" @default.
• W4311890042 hasPublicationYear "2022" @default.
• W4311890042 type Work @default.
• W4311890042 citedByCount "0" @default.
• W4311890042 crossrefType "journal-article" @default.
• W4311890042 hasAuthorship W4311890042A5042620576 @default.
• W4311890042 hasAuthorship W4311890042A5074366172 @default.
• W4311890042 hasBestOaLocation W43118900421 @default.
• W4311890042 hasConcept C126322002 @default.
• W4311890042 hasConcept C131872663 @default.
• W4311890042 hasConcept C134018914 @default.
• W4311890042 hasConcept C172680121 @default.
• W4311890042 hasConcept C2776886772 @default.
• W4311890042 hasConcept C2776953305 @default.
• W4311890042 hasConcept C2778376644 @default.
• W4311890042 hasConcept C2779234561 @default.
• W4311890042 hasConcept C2779434492 @default.
• W4311890042 hasConcept C2781291890 @default.
• W4311890042 hasConcept C46973012 @default.
• W4311890042 hasConcept C54355233 @default.
• W4311890042 hasConcept C555293320 @default.
• W4311890042 hasConcept C58471807 @default.
• W4311890042 hasConcept C71924100 @default.
• W4311890042 hasConcept C86803240 @default.
• W4311890042 hasConceptScore W4311890042C126322002 @default.
• W4311890042 hasConceptScore W4311890042C131872663 @default.
• W4311890042 hasConceptScore W4311890042C134018914 @default.
• W4311890042 hasConceptScore W4311890042C172680121 @default.
• W4311890042 hasConceptScore W4311890042C2776886772 @default.
• W4311890042 hasConceptScore W4311890042C2776953305 @default.
• W4311890042 hasConceptScore W4311890042C2778376644 @default.
• W4311890042 hasConceptScore W4311890042C2779234561 @default.
• W4311890042 hasConceptScore W4311890042C2779434492 @default.
• W4311890042 hasConceptScore W4311890042C2781291890 @default.
• W4311890042 hasConceptScore W4311890042C46973012 @default.
• W4311890042 hasConceptScore W4311890042C54355233 @default.
• W4311890042 hasConceptScore W4311890042C555293320 @default.
• W4311890042 hasConceptScore W4311890042C58471807 @default.
• W4311890042 hasConceptScore W4311890042C71924100 @default.
• W4311890042 hasConceptScore W4311890042C86803240 @default.
• W4311890042 hasLocation W43118900421 @default.
• W4311890042 hasOpenAccess W4311890042 @default.
• W4311890042 hasPrimaryLocation W43118900421 @default.
• W4311890042 hasRelatedWork W1996159008 @default.
• W4311890042 hasRelatedWork W2052689364 @default.
• W4311890042 hasRelatedWork W2163638983 @default.
• W4311890042 hasRelatedWork W2333891256 @default.
• W4311890042 hasRelatedWork W2348658402 @default.
• W4311890042 hasRelatedWork W2350321065 @default.
• W4311890042 hasRelatedWork W3087313521 @default.
• W4311890042 hasRelatedWork W3108178219 @default.
• W4311890042 hasRelatedWork W3145636702 @default.
• W4311890042 hasRelatedWork W4323840584 @default.
• W4311890042 isParatext "false" @default.
• W4311890042 isRetracted "false" @default.
• W4311890042 workType "article" @default.