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• W4311894652 abstract "Abstract Background End-stage renal disease (ESRD) incidence has increased recently. Maintenance hemodialysis (MHD), which removes squandering and extra fluid from the blood while maintaining electrolyte balance, is a commonly used treatment for people with ESRD. MHD decreases the likelihood of ESRD complications while enhancing the quality of life. Therefore, MHD is an important treatment option for patients with ESRD. Objectives The study aimed to investigate the correlation between the influencing factors and quality of life in patients receiving MHD and to provide a theoretical basis for clinical medical workers to carry out targeted treatment and nursing of patients receiving MHD. Material and Methods Participants were recruited from the Blood Purification Center of a tertiary hospital in Wuhu City, a total of 147 samples received MHD treatment since 2015. Standardized interviews were conducted with 147 patients. The EQ-5D-5L, Kessler10, SRSS, and FRAIL scales, measure various aspects of life quality, mental health, sleep quality, and debilitating status, respectively. And structural equation model of influencing factors related to the quality of life was constructed. Results The UI (Mean = 0.82) for 147 participants was lower than normal (Mean = 0.98). There were significant differences in UI effect values in patients receiving MHD of different ages, education levels, exercise habits, sleep duration, primary disease, and comorbidity (all P < 0.05), and CVAS effect values between patients receiving MHD with different family locations, primary diseases, comorbidity and erythromycin-stimulating frequency (all P < 0.05). There was a positive correlation between the degree of frailty and the quality of life of patients receiving MHD ( P = 0.034). There was a negative correlation between mental state and quality of life ( P < 0.001) and a negative correlation between sleep quality and mental state ( P < 0.001). Psychological status played a mediating role between sleep quality and quality of life in patients with MHD (Effect value is 0.005, P = 0.001 < 0.05). Conclusion Patients on maintenance hemodialysis have a poor quality of life. The quality of life is influenced by a variety of factors. To lessen the burden of symptoms and enhance patients' quality of life, customized nursing interventions should be developed following the individual conditions of each patient." @default.
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• W4311894652 date "2022-12-19" @default.
• W4311894652 modified "2023-10-14" @default.
• W4311894652 title "Path analysis of the role of frailty, psychological state, and sleep quality on quality of life in patients receiving maintenance haemodialysis" @default.
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• W4311894652 doi "https://doi.org/10.21203/rs.3.rs-2340790/v1" @default.
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