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• W4311907159 abstract "The TARGIT-A trial demonstrated that targeted intraoperative radiation therapy (TARGIT-IORT) during lumpectomy as a risk-adapted approach achieves breast cancer outcomes (local control, breast preservation, freedom from distant disease, and breast cancer mortality) comparable with whole breast external beam radiation therapy (EBRT) in both the short term and the long term 1 Vaidya JS Bulsara M Baum M et al. Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial. BMJ. 2020; 370: m2836 Crossref PubMed Scopus (137) Google Scholar , 2 Vaidya JS Bulsara M Baum M et al. New clinical and biological insights from the international TARGIT-A randomised trial of targeted intraoperative radiotherapy during lumpectomy for breast cancer. Br J Cancer. 2021; 125: 380-389 Crossref PubMed Scopus (20) Google Scholar , 3 Vaidya JS Bulsara M Baum M Tobias JS. Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: An innovative patient-centred treatment. Br J Cancer. 2021; 124: 1469-1474 Crossref PubMed Scopus (12) Google Scholar and provides survival benefits. Randomization in the trial at such a large scale has ensured that risk factors for death and breast cancer outcomes were equally distributed between the two arms of the trial, so that the differences or equality observed for both these outcomes must be attributed to the differences or equality in the effects of the treatment." @default.
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• W4311907159 date "2023-01-01" @default.
• W4311907159 modified "2023-09-30" @default.
• W4311907159 title "In Reply to Ward et al." @default.
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• W4311907159 doi "https://doi.org/10.1016/j.ijrobp.2022.10.009" @default.
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