FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311948662> ?p ?o ?g. }

• W4311948662 abstract "Purpose The aim of this study is to evaluate the role of regional nodal irradiation (RNI) in patients with T1-2N1M0 breast cancer and to identify the subgroup that could benefit from RNI. Methods and materials A total of 4,243 women with pT1-2N1M0 breast cancer treated at two institutions in China were retrospectively reviewed. Survival rates were calculated by the Kaplan–Meier method and compared by the log-rank test. The association of risk factors with survival outcomes was evaluated using multivariable proportional hazards regression. Results A total of 932 patients (22.0%) received RNI. At a median follow-up of 5.9 years, the 5-year locoregional recurrence (LRR), distant metastasis (DM), disease-free survival (DFS), and overall survival (OS) rates were 4.0% and 7.2% ( P = 0.001), 13.2% and 10.6% ( P = 0.465), 85.0% and 84.7% ( P = 0.131), and 93.9% and 92.8% ( P = 0.004) in the RNI and non-RNI groups, respectively. Multivariate analysis revealed that RNI was an independent prognostic factor for lower LRR ( P = 0.001) and longer DFS ( P = 0.013). Patients were stratified into low-, intermediate-, and high-risk groups based on the eight non-therapeutic risk factors. RNI significantly decreased the 5-year LRR (2.2% vs. 7.0%, P = 0.001) and improved the 5-year DFS (88.8% vs. 84.9%, P = 0.015) and OS (95.8% vs. 93.9%, P = 0.010) in the intermediate-risk group. However, neither the low-risk group nor the high-risk group had survival benefit from RNI. Conclusion T1-2N1M0 breast cancer is a heterogeneous disease. We found that RNI only improved survival in the intermediate-risk group. It might be omitted in low-risk patients, and the role of RNI in high-risk patients needs further study." @default.
• W4311948662 created "2023-01-03" @default.
• W4311948662 creator A5002425899 @default.
• W4311948662 creator A5005360514 @default.
• W4311948662 creator A5008742634 @default.
• W4311948662 creator A5013115993 @default.
• W4311948662 creator A5013850008 @default.
• W4311948662 creator A5015732550 @default.
• W4311948662 creator A5015924742 @default.
• W4311948662 creator A5019572565 @default.
• W4311948662 creator A5021026164 @default.
• W4311948662 creator A5027861145 @default.
• W4311948662 creator A5027862802 @default.
• W4311948662 creator A5028731046 @default.
• W4311948662 creator A5028809442 @default.
• W4311948662 creator A5031810848 @default.
• W4311948662 creator A5040890204 @default.
• W4311948662 creator A5050067556 @default.
• W4311948662 creator A5067483347 @default.
• W4311948662 creator A5067714130 @default.
• W4311948662 creator A5082156574 @default.
• W4311948662 creator A5084229837 @default.
• W4311948662 date "2022-12-20" @default.
• W4311948662 modified "2023-10-16" @default.
• W4311948662 title "Risk factors to identify the indication for regional nodal irradiation in T1-2N1M0 breast cancer: A joint analysis of 4,243 real-world cases from two institutions" @default.
• W4311948662 cites W1770259999 @default.
• W4311948662 cites W1897907766 @default.
• W4311948662 cites W1948261638 @default.
• W4311948662 cites W1978767656 @default.
• W4311948662 cites W2002714578 @default.
• W4311948662 cites W2046826982 @default.
• W4311948662 cites W2060250348 @default.
• W4311948662 cites W2062298610 @default.
• W4311948662 cites W2075153856 @default.
• W4311948662 cites W2087263485 @default.
• W4311948662 cites W2088597767 @default.
• W4311948662 cites W2092950740 @default.
• W4311948662 cites W2096490429 @default.
• W4311948662 cites W2100025800 @default.
• W4311948662 cites W2104157423 @default.
• W4311948662 cites W2112745405 @default.
• W4311948662 cites W2129825983 @default.
• W4311948662 cites W2131341595 @default.
• W4311948662 cites W2138652241 @default.
• W4311948662 cites W2141643514 @default.
• W4311948662 cites W2176010689 @default.
• W4311948662 cites W2534719059 @default.
• W4311948662 cites W2595436678 @default.
• W4311948662 cites W2790356602 @default.
• W4311948662 cites W2799338871 @default.
• W4311948662 cites W2809638229 @default.
• W4311948662 cites W2899302964 @default.
• W4311948662 cites W2900372890 @default.
• W4311948662 cites W2951982561 @default.
• W4311948662 cites W2991516615 @default.
• W4311948662 cites W3009236820 @default.
• W4311948662 cites W3015987129 @default.
• W4311948662 cites W3097739674 @default.
• W4311948662 cites W3183282470 @default.
• W4311948662 cites W3208809333 @default.
• W4311948662 cites W4307224183 @default.
• W4311948662 cites W993406450 @default.
• W4311948662 doi "https://doi.org/10.3389/fonc.2022.955381" @default.
• W4311948662 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36605447" @default.
• W4311948662 hasPublicationYear "2022" @default.
• W4311948662 type Work @default.
• W4311948662 citedByCount "0" @default.
• W4311948662 crossrefType "journal-article" @default.
• W4311948662 hasAuthorship W4311948662A5002425899 @default.
• W4311948662 hasAuthorship W4311948662A5005360514 @default.
• W4311948662 hasAuthorship W4311948662A5008742634 @default.
• W4311948662 hasAuthorship W4311948662A5013115993 @default.
• W4311948662 hasAuthorship W4311948662A5013850008 @default.
• W4311948662 hasAuthorship W4311948662A5015732550 @default.
• W4311948662 hasAuthorship W4311948662A5015924742 @default.
• W4311948662 hasAuthorship W4311948662A5019572565 @default.
• W4311948662 hasAuthorship W4311948662A5021026164 @default.
• W4311948662 hasAuthorship W4311948662A5027861145 @default.
• W4311948662 hasAuthorship W4311948662A5027862802 @default.
• W4311948662 hasAuthorship W4311948662A5028731046 @default.
• W4311948662 hasAuthorship W4311948662A5028809442 @default.
• W4311948662 hasAuthorship W4311948662A5031810848 @default.
• W4311948662 hasAuthorship W4311948662A5040890204 @default.
• W4311948662 hasAuthorship W4311948662A5050067556 @default.
• W4311948662 hasAuthorship W4311948662A5067483347 @default.
• W4311948662 hasAuthorship W4311948662A5067714130 @default.
• W4311948662 hasAuthorship W4311948662A5082156574 @default.
• W4311948662 hasAuthorship W4311948662A5084229837 @default.
• W4311948662 hasBestOaLocation W43119486621 @default.
• W4311948662 hasConcept C10515644 @default.
• W4311948662 hasConcept C121608353 @default.
• W4311948662 hasConcept C126322002 @default.
• W4311948662 hasConcept C143998085 @default.
• W4311948662 hasConcept C38180746 @default.
• W4311948662 hasConcept C50382708 @default.
• W4311948662 hasConcept C530470458 @default.
• W4311948662 hasConcept C71924100 @default.
• W4311948662 hasConcept C90924648 @default.
• W4311948662 hasConceptScore W4311948662C10515644 @default.
• W4311948662 hasConceptScore W4311948662C121608353 @default.

• next