Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312036836> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W4312036836 endingPage "752" @default.
- W4312036836 startingPage "752" @default.
- W4312036836 abstract "Abstract Prevalence of frailty among older sexual and gender minority adults (OSGM) is unknown despite disparities in mental health, medical comorbidities, and physical function. The NIH-funded All of Us Program was launched May 2018 aiming to enroll 1 million US participants focusing on those underrepresented in biomedical research, including OSGM. Using validated methods, we developed an All of Us deficit accumulation frailty index (AoU-FI) consisting of 33-items using baseline survey responses of adults aged 50+. Deficit domains include comorbidities, physical functioning, mental health, cognition, and sensory impairment. AoU-FI was valid if ≤20% of items were missing and ≤70% were comorbidities. OSGM self-identified or had discordance between gender and sex responses. OSGM (n=5,678) and non-OSGM (n=66,325), were similar in age (mean (IQR) = 66.7 (60–73) vs 66.9 (60–74)) but were more diverse (White 78% vs 82%, Black 7.5% vs. 6.5%, Hispanic/Latino 6.9% vs. 5.9%). AoU-FI had an expected gamma distribution across groups. OSGM frailty had a narrower range (0–0.67 vs. 0–0.75) and higher mean of 0.19 (sd=0.11) vs 0.17 (sd=0.1) compared to non-OSGM. To our knowledge, this is the first study of frailty among OSGM. Findings suggest OSGM experience worse frailty, highlighting the need to understand disparities in frailty, identify interventions, and develop policies to support OSGM. Additionally, our novel AoU-FI creates opportunities to apply frailty to diverse participants and types of data from digital health to genomics within the All of Us database." @default.
- W4312036836 created "2023-01-04" @default.
- W4312036836 creator A5001469181 @default.
- W4312036836 creator A5007259981 @default.
- W4312036836 creator A5038196934 @default.
- W4312036836 creator A5043326123 @default.
- W4312036836 creator A5056263425 @default.
- W4312036836 creator A5058596390 @default.
- W4312036836 creator A5072936885 @default.
- W4312036836 date "2022-11-01" @default.
- W4312036836 modified "2023-09-23" @default.
- W4312036836 title "DEVELOPING A NOVEL FRAILTY INDEX TO STUDY FRAILTY OF SEXUAL AND GENDER MINORITY OLDER ADULTS IN THE ALL OF US DATABASE" @default.
- W4312036836 doi "https://doi.org/10.1093/geroni/igac059.2733" @default.
- W4312036836 hasPublicationYear "2022" @default.
- W4312036836 type Work @default.
- W4312036836 citedByCount "0" @default.
- W4312036836 crossrefType "journal-article" @default.
- W4312036836 hasAuthorship W4312036836A5001469181 @default.
- W4312036836 hasAuthorship W4312036836A5007259981 @default.
- W4312036836 hasAuthorship W4312036836A5038196934 @default.
- W4312036836 hasAuthorship W4312036836A5043326123 @default.
- W4312036836 hasAuthorship W4312036836A5056263425 @default.
- W4312036836 hasAuthorship W4312036836A5058596390 @default.
- W4312036836 hasAuthorship W4312036836A5072936885 @default.
- W4312036836 hasBestOaLocation W43120368361 @default.
- W4312036836 hasConcept C118552586 @default.
- W4312036836 hasConcept C134362201 @default.
- W4312036836 hasConcept C169900460 @default.
- W4312036836 hasConcept C27415008 @default.
- W4312036836 hasConcept C2909041561 @default.
- W4312036836 hasConcept C2984915365 @default.
- W4312036836 hasConcept C71924100 @default.
- W4312036836 hasConcept C74909509 @default.
- W4312036836 hasConceptScore W4312036836C118552586 @default.
- W4312036836 hasConceptScore W4312036836C134362201 @default.
- W4312036836 hasConceptScore W4312036836C169900460 @default.
- W4312036836 hasConceptScore W4312036836C27415008 @default.
- W4312036836 hasConceptScore W4312036836C2909041561 @default.
- W4312036836 hasConceptScore W4312036836C2984915365 @default.
- W4312036836 hasConceptScore W4312036836C71924100 @default.
- W4312036836 hasConceptScore W4312036836C74909509 @default.
- W4312036836 hasIssue "Supplement_1" @default.
- W4312036836 hasLocation W43120368361 @default.
- W4312036836 hasLocation W43120368362 @default.
- W4312036836 hasOpenAccess W4312036836 @default.
- W4312036836 hasPrimaryLocation W43120368361 @default.
- W4312036836 hasRelatedWork W1531808129 @default.
- W4312036836 hasRelatedWork W2069510972 @default.
- W4312036836 hasRelatedWork W2079390537 @default.
- W4312036836 hasRelatedWork W2196008146 @default.
- W4312036836 hasRelatedWork W2278469921 @default.
- W4312036836 hasRelatedWork W2392637812 @default.
- W4312036836 hasRelatedWork W2622013112 @default.
- W4312036836 hasRelatedWork W3030527225 @default.
- W4312036836 hasRelatedWork W4319039714 @default.
- W4312036836 hasRelatedWork W4379745952 @default.
- W4312036836 hasVolume "6" @default.
- W4312036836 isParatext "false" @default.
- W4312036836 isRetracted "false" @default.
- W4312036836 workType "article" @default.