Matches in SemOpenAlex for { <https://semopenalex.org/work/W4312085807> ?p ?o ?g. }
- W4312085807 endingPage "1844" @default.
- W4312085807 startingPage "1829" @default.
- W4312085807 abstract "Improvements in systemic therapy in the treatment of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) have improved patient outcomes and reduced the incidence of CNS relapse. However, management of patients with CNS disease remains challenging, and relapses in the CNS can be difficult to salvage. In addition to treatment with CNS-penetrant systemic therapy (high-dose methotrexate and cytarabine), intrathecal prophylaxis is indicated in all patients with ALL, however is not uniformly administered in patients with AML without high-risk features. There is a limited role for radiation treatment in CNS prophylaxis; however, radiation should be considered for consolidative treatment in patients with CNS disease, or as an option for palliation of symptoms. Re-examining the role of established treatment paradigms and investigating the role of radiation as bridging therapy in the era of cellular therapy, particularly in chemotherapy refractory patients, is warranted." @default.
- W4312085807 created "2023-01-04" @default.
- W4312085807 creator A5007688820 @default.
- W4312085807 creator A5037180937 @default.
- W4312085807 creator A5069043926 @default.
- W4312085807 creator A5083226997 @default.
- W4312085807 creator A5091492845 @default.
- W4312085807 date "2022-12-01" @default.
- W4312085807 modified "2023-09-30" @default.
- W4312085807 title "Central Nervous System Prophylaxis and Treatment in Acute Leukemias" @default.
- W4312085807 cites W121090805 @default.
- W4312085807 cites W148262973 @default.
- W4312085807 cites W1525126309 @default.
- W4312085807 cites W1574752843 @default.
- W4312085807 cites W184551449 @default.
- W4312085807 cites W1974276386 @default.
- W4312085807 cites W1975280591 @default.
- W4312085807 cites W1981552257 @default.
- W4312085807 cites W1993228380 @default.
- W4312085807 cites W1993312424 @default.
- W4312085807 cites W1994004225 @default.
- W4312085807 cites W1996096852 @default.
- W4312085807 cites W2006643614 @default.
- W4312085807 cites W2013070127 @default.
- W4312085807 cites W2013414992 @default.
- W4312085807 cites W2027150427 @default.
- W4312085807 cites W2028898086 @default.
- W4312085807 cites W2032346182 @default.
- W4312085807 cites W2050247348 @default.
- W4312085807 cites W2053258621 @default.
- W4312085807 cites W2058326606 @default.
- W4312085807 cites W2059028767 @default.
- W4312085807 cites W2059999488 @default.
- W4312085807 cites W2060974470 @default.
- W4312085807 cites W2061453199 @default.
- W4312085807 cites W2064586045 @default.
- W4312085807 cites W2068835290 @default.
- W4312085807 cites W2075506450 @default.
- W4312085807 cites W2081127271 @default.
- W4312085807 cites W2098676147 @default.
- W4312085807 cites W2102814382 @default.
- W4312085807 cites W2109111809 @default.
- W4312085807 cites W2111406583 @default.
- W4312085807 cites W2116858301 @default.
- W4312085807 cites W2125486570 @default.
- W4312085807 cites W2130118065 @default.
- W4312085807 cites W2139106474 @default.
- W4312085807 cites W2151855555 @default.
- W4312085807 cites W2166295047 @default.
- W4312085807 cites W2171718529 @default.
- W4312085807 cites W2238009057 @default.
- W4312085807 cites W2272408689 @default.
- W4312085807 cites W2285218518 @default.
- W4312085807 cites W2328693217 @default.
- W4312085807 cites W2536237561 @default.
- W4312085807 cites W2558579148 @default.
- W4312085807 cites W2591200814 @default.
- W4312085807 cites W2591709377 @default.
- W4312085807 cites W2596725109 @default.
- W4312085807 cites W2613787350 @default.
- W4312085807 cites W2618802256 @default.
- W4312085807 cites W2677241204 @default.
- W4312085807 cites W2787145330 @default.
- W4312085807 cites W2787301955 @default.
- W4312085807 cites W2799271863 @default.
- W4312085807 cites W2802984873 @default.
- W4312085807 cites W2806004290 @default.
- W4312085807 cites W2891253541 @default.
- W4312085807 cites W2899794039 @default.
- W4312085807 cites W2919881382 @default.
- W4312085807 cites W2984002264 @default.
- W4312085807 cites W2990912935 @default.
- W4312085807 cites W2994491754 @default.
- W4312085807 cites W2998095957 @default.
- W4312085807 cites W3002684411 @default.
- W4312085807 cites W3030234447 @default.
- W4312085807 cites W3164628251 @default.
- W4312085807 cites W3165168927 @default.
- W4312085807 cites W3169193862 @default.
- W4312085807 cites W3184155393 @default.
- W4312085807 cites W3199106862 @default.
- W4312085807 cites W3202052032 @default.
- W4312085807 cites W4210921462 @default.
- W4312085807 cites W4220685620 @default.
- W4312085807 cites W886894 @default.
- W4312085807 doi "https://doi.org/10.1007/s11864-022-01032-5" @default.
- W4312085807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36510037" @default.
- W4312085807 hasPublicationYear "2022" @default.
- W4312085807 type Work @default.
- W4312085807 citedByCount "2" @default.
- W4312085807 countsByYear W43120858072023 @default.
- W4312085807 crossrefType "journal-article" @default.
- W4312085807 hasAuthorship W4312085807A5007688820 @default.
- W4312085807 hasAuthorship W4312085807A5037180937 @default.
- W4312085807 hasAuthorship W4312085807A5069043926 @default.
- W4312085807 hasAuthorship W4312085807A5083226997 @default.
- W4312085807 hasAuthorship W4312085807A5091492845 @default.
- W4312085807 hasBestOaLocation W43120858071 @default.